Dynorphin Neuropeptides Decrease Apparent Proton Affinity of ASIC1a by Occluding the Acidic Pocket by Lilia Leisle (11356934)

“…We confirmed experimentally that the interaction is predominantly driven by electrostatic forces, and using noncanonical amino acids as photo-cross-linkers, we identified 16 residues in ASIC1a contributing to Big Dyn binding. Covalently tethering Big Dyn to its ASIC1a binding site dramatically decreased the proton sensitivity of channel activation, suggesting that Big Dyn stabilizes a resting conformation of ASIC1a and dissociates from its binding site during channel opening.…”

The HMR C-terminus is required for HMR localization in proximity to centromeres and HP1a-bound chromatin (related to Fig 4A and 5). by Andrea Lukacs (3752956)

GluN2A(D731N) decreases current amplitudes and shortens synaptic-like response time course. by Kai Gao (120150)

Subjects:

Tornado diagram showing the results of a one-way sensitivity analysis conducted for the scenario without vaccination. by Albertus Constantijn Sloof (20405090)

Decreased activity of FASII favors the cold growth of the <i>ΔcshA</i> strain. by Vanessa Khemici (814639)

“…<p><b>(A)</b><i>fapR</i> mRNA levels decrease in ACC and biotin related suppressor strains. …”

Cryo-electron tomography of a FC reveals linear, periodical protein arrangements in the interstitial zone. by Johanna L. Höög (402710)

“…<p><b>A)</b> An overview of the cryo-section shows the old flagellum, new flagellum tip and the cell body sectioned transversally to the cells longitudinal axis. …”

JNK inhibitor AS601245 decreased levels of Bim and CC3 proteins and reduced neuronal apoptosis and brain infarct volume in P7 rat after HI. by Deyuan Li (769599)

“…The infarct volume in the AS601245-treated brain was decreased by 58% compared with the DMSO controls (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132998#pone.0132998.g004" target="_blank">Fig 4I</a>).…”

Assays of TUNEL revealed a decreased number of apoptotic cell after oroxylin A treatment. by Shu-Fang Lin (4167091)

Long-term trends in inflowing chlorophyll <i>a</i> and nutrients and their relation to dissolved oxygen in a large western reservoir by Jesse Naymik (9128597)

“…Long-term trends in inflowing chlorophyll <i>a</i> and nutrients and their relation to dissolved oxygen in a large western reservoir. …”

Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport Chain Enzyme Activities Are Altered in n-3 Enriched <em>fat-1</em> Mice by Kevork Hagopian (242070)

“…This change in H₂O₂ production was due to a decrease in ROS production from ETC complex I in the <em>fat-1</em> animals. …”

<i>Gli1</i> Haploinsufficiency Leads to Decreased Bone Mass with an Uncoupling of Bone Metabolism in Adult Mice by Yoshiaki Kitaura (644233)

“…Skeletal analyses of <i>Gli1</i>^+/− adult mice revealed that <i>Gli1</i> haploinsufficiency caused decreased bone mass with reduced bone formation and accelerated bone resorption, suggesting an uncoupling of bone metabolism. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…Maternal peripheral leukocytes can be used to monitor a variety of physiological processes occurring in the body. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…Maternal peripheral leukocytes can be used to monitor a variety of physiological processes occurring in the body. …”

ΔNp63α over-expression in NOKs-Akata cells during differentiation decreases EBV lytic reactivation. by Nicholas Van Sciver (8452521)

A selection of pain distributions reported by patients in Cluster #2. by Gerhard Fritsch (405224)

Subjects:

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)

Multiple linear regression models of fetal NT and plasma trace element levels in primiparas and multiparas. by Kai-Wei Liao (620360)

MAP-map analysis of activity decreases within olfactory bulb and preoptic dopaminergic regions. by Jessica C. Nelson (10906236)

Within-race sex disparities in COVID-19 incidence and mortality. by Max Jordan Nguemeni Tiako (11442284)

Supplementary Material for: Intestinal Vascular Endothelial Growth Factor Is Decreased in Necrotizing Enterocolitis by Sabnis A. (4149406)

“…<b><i>Objectives:</i></b> The objective of this study was to determine whether intestinal VEGF expression is altered in a neonatal mouse model of NEC and in human NEC patients. …”