Image4_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…Luciferase activity analysis confirmed heightened NF-ĸB transcriptional activity in FGFR1-overexpressing BEAS-2B cells and BEAS-2B cells treated with 5-Aza-CdR. Additionally, a decrease in methylation levels in the FGFR1 DNA promoter was detected in the serum of asthma patients using the MassARRAY technique.…”

DataSheet1_Analysis of air pollution characteristics, transport pathways and potential source areas identification in Beijing before, during and after the COVID-19 outbreak.docx by Hanyu Zhang (1425250)

“…O₃ concentrations increased by 174.8% compared to that during the BCO period due to the increased temperature and inappropriate precursor reduction ratios. A considerable decrease of NO₃^- in PM_2.5 was observed under the influence of significant reductions in vehicle emissions during the lockdown. …”

DataSheet_4_Mucosal-associated invariant T cells repress group 2 innate lymphoid cells in Alternaria alternata-induced model of allergic airway inflammation.pdf by Yasuo Shimizu (3521666)

“…We concluded that MAIT cells played a crucial role in suppressing the cytokine-producing capacity of ILC2s and ILC2 proliferation, that ultimately led to decrease in the allergic airway inflammation.…”

Table_2_10-year time course of Hg and organic compounds in Augusta Bay: Bioavailability and biological effects in marine organisms.DOCX by Maura Benedetti (72401)

“…While levels of chemicals in sediments remained elevated during the time course, their bioavailability and biological effects showed a gradual decrease after 2003, when the chlor-alkali plant was closed. …”

Safety and Feasibility of Long-term Intravenous Sodium Nitrite Infusion in Healthy Volunteers by Ryszard M. Pluta (233325)

“…Dose limiting toxicity occurred at 446 µg/kg/hr. Toxicity included a transient asymptomatic decrease of mean arterial blood pressure (more than 15 mmHg) and/or an asymptomatic increase of methemoglobin level above 5%. …”

DataSheet_5_Mucosal-associated invariant T cells repress group 2 innate lymphoid cells in Alternaria alternata-induced model of allergic airway inflammation.pdf by Yasuo Shimizu (3521666)

“…We concluded that MAIT cells played a crucial role in suppressing the cytokine-producing capacity of ILC2s and ILC2 proliferation, that ultimately led to decrease in the allergic airway inflammation.…”

Image4_Impact of the COVID-19 Pandemic on the Diagnosis of Tuberculosis in Brazil: Is the WHO End TB Strategy at Risk?.tif by Mariana do Rosário Souza (9751424)

“…</p><p>Interpretation: Taken together, our analyses demonstrated a reduction in TB diagnosis after the irruption of the COVID-19 pandemic in Brazil and its regions, signaling a serious impact on the WHO “End TB Strategy” global plan.…”

mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the... by Manabu Taneike (3214956)

“…Ultrastructural analysis of <i>TSC2</i>^-/- hearts revealed misalignment, aggregation and a decrease in the size and an increase in the number of mitochondria, but the mitochondrial function was maintained. …”

Data_Sheet_1_Identification of differentially expressed mRNAs and miRNAs in spermatozoa of bulls of varying fertility.docx by Eimear M. Donnellan (13908018)

“…In contrast, Western Blot analysis revealed a decrease in PRM1 protein abundance for spermatozoa from LF bulls; this was not associated with increased protamine deficiency (measured by the degree of chromatin compaction) or DNA fragmentation, as assessed by flow cytometry analyses. …”

DataSheet_1_Transcriptome and metabolome analysis reveals the effect of flavonoids on flower color variation in Dendrobium nobile Lindl..zip by Yujie Qiu (16868841)

“…The metabolomics results at S3 found 129 differentially accumulated metabolites (DAMs), which included 8 anthocyanin metabolites, all of which (with the exception of delphinidin-3-o-(2’’’-o-malonyl) sophoroside-5-o-glucoside) were found at lower amounts in the WF variety compared with the PF variety, indicating that a decrease in the anthocyanin content was the main reason for the inability to form purple flowers. …”

Image_2_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…The double mutation C156A/R159A decreases Ca²⁺/CaM binding and completely abolishes CaM-mediated calcium-dependent regulation of Kv7.4 activation. …”

Table_1_Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota.DOCX by Ke-Jie He (13239966)

“…In addition, LPMCs extracted from intestinal tissue via flow cytometry showed that GML treatment led to a decrease of Th17 cells, Neutrophils and Macrophages. 16S rDNA sequencing showed that GML increased the abundance of commensal bacterium such as Akkermansia and Lactobacillus murinus.…”

Table_1_Controlled Reduction of Genomic Heterozygosity in an Industrial Yeast Strain Reveals Wide Cryptic Phenotypic Variation.xlsx by Nadia M. V. Sampaio (5330723)

“…However, we propose that homozygosity for those regions may be associated with a decrease in overall fitness in the complex and dynamic distillery environment, and that may have contributed to slowing down the erosion of heterozygosity from the JAY270 genome. …”

Table_1_Impact of selenium on the intestinal microbiome-eCBome axis in the context of diet-related metabolic health in mice.xlsx by Fredy Alexander Guevara Agudelo (14104119)

“…With respect to the intestinal immune response and anti-oxidative gene expression, we observed a decrease in the expression of proinflammatory genes Il1β and Tnfα in high-fat Se-enriched diets in caecum, while in ileum an increase in the expression levels of the antioxidant gene Gpx4 was observed following Se depletion. …”

Comparative Internal and External AUC Performance Across Single-Site Models. by Ioana Duta (18462981)

“…At Agincourt, the internal AUC is 0.96 (interquartile range (IQR) 0.95–0.97), while the external AUC is 0.88 (IQR 0.86–0.88), demonstrating a statistically significant difference with a decrease of approximately 0.08 in performance when models are externally validated. …”

Preconditioning with Associated Blocking of Ca²⁺ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells by Zuheng Ma (225476)

“…Preconditioning with diazoxide or other agents was usually done during a 22 h period prior to hypoxia.</p><p>Results</p><p>Insulin contents decreased by 23% after 5.5 h of hypoxia and by 61% after a re-oxygenation period. …”

Image_7_The S2–S3 Loop of Kv7.4 Channels Is Essential for Calmodulin Regulation of Channel Activation.tif by Wenhui Zhuang (10007378)

“…The double mutation C156A/R159A decreases Ca²⁺/CaM binding and completely abolishes CaM-mediated calcium-dependent regulation of Kv7.4 activation. …”

DataSheet_3_Mucosal-associated invariant T cells repress group 2 innate lymphoid cells in Alternaria alternata-induced model of allergic airway inflammation.pdf by Yasuo Shimizu (3521666)

“…We concluded that MAIT cells played a crucial role in suppressing the cytokine-producing capacity of ILC2s and ILC2 proliferation, that ultimately led to decrease in the allergic airway inflammation.…”

Table 1_The global burden of aortic aneurysm in adults over 55: evolving trends, risk factors, and projections.pdf by Guoqian Ma (22253182)

“…Similar patterns were observed for DALYs, with a 62.6% increase in total DALYs but a 26.5% decrease in rates. …”

DataSheet1_Impact of the COVID-19 Pandemic on the Diagnosis of Tuberculosis in Brazil: Is the WHO End TB Strategy at Risk?.docx by Mariana do Rosário Souza (9751424)

“…</p><p>Interpretation: Taken together, our analyses demonstrated a reduction in TB diagnosis after the irruption of the COVID-19 pandemic in Brazil and its regions, signaling a serious impact on the WHO “End TB Strategy” global plan.…”