Table 1_The clinical prediction model to distinguish between colonization and infection by Klebsiella pneumoniae.xlsx by Xiaoyu Zhang (62901)

“…The importance of each factor was demonstrated using mean decrease in Gini. “Admitted with a diagnosis of respiratory infectious disease” (8.39) was identified as the most important factor in the model, followed by “Hypoalbuminemia” (7.83), then “ESBL” (7.06), “Electrolyte Imbalance” (5.81), “Age > 62 years” (5.24), “The number of Positive Sputum Cultures for KP > 2” (4.77), and being bedridden (4.24). …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Detecting and Destroying Cancer Cells in More than One Way with Noble Metals and Different Confinement Properties on the Nanoscale by Erik C. Dreaden (1316589)

“…However, as improved detection and increasing exposure to carcinogens has led to higher rates of cancer incidence, clinicians and researchers have not balanced that increase with a similar decrease in cancer mortality rates. This mismatch highlights a clear and urgent need for increasingly potent and selective methods with which to detect and treat cancers at their earliest stages.Nanotechnology, the use of materials with structural features ranging from 1 to 100 nm in size, has dramatically altered the design, use, and delivery of cancer diagnostic and therapeutic agents. …”

Data_Sheet_1_Sustained Release of Phosphates From Hydrogel Nanoparticles Suppresses Bacterial Collagenase and Biofilm Formation in vitro.PDF by Dylan Nichols (6880322)

“…<p>Intestinal disease or surgical intervention results in local changes in tissue and host-derived factors triggering bacterial virulence. A key phenotype involved in impaired tissue healing is increased bacterial collagenase expression which degrades intestinal collagen. …”

Table_1_ACC deaminase-producing endophytic fungal consortia promotes drought stress tolerance in M.oleifera by mitigating ethylene and H2O2.docx by Bushra Rehman (14292428)

“…The co-inoculum (TP+TR) also induced the antioxidant potential and enzyme activities POX (325%), CAT activity (166%), and AsA (21%), along with a lesser decrease (-2%) in water potential in M. oleifera plants with co-inoculation under water deficit compared with non-inoculated control. …”

Rate of cell division in vascular lesions is related to Tcf21 expression. by Sylvia T. Nurnberg (5663650)

“…EdU fluorescence (green) was merged with red pseudocolored DAPI fluorescence, yellow arrows indicate yellow nuclei that are positive for both EdU and DAPI fluorescence. E) A statistically significant decrease in this percentage in <i>Tcf21</i>^{<i>lacZ/+</i>}, <i>ApoE</i>^<i>-/-</i> animals compared to <i>ApoE</i>^<i>-/-</i> animals suggested a correlation between <i>Tcf21</i> expression and rate of cell division in the vascular lesions. …”

Loss of SNX-3 leads to misrouting of hTAC away from the recycling pathway. by Yangli Tian (4871416)

“…<p>(A) Micrographs taken with a 150× objective showing the detailed architecture and location of RFP-RME-1-labeled basolateral recycling endosomes with respect to hTAC-GFP-containing carriers. …”

DataSheet_2_Cyclic adenosine monophosphate/phosphodiesterase 4 pathway associated with immune infiltration and PD-L1 expression in lung adenocarcinoma cells.zip by Ling Tong (632992)

“…In the cell experiment, forskolin (an adenylate cyclase activator) and zardaverine (a PDE4 inhibitor) enhance the cAMP pathway and decrease PD-L1 expression, while SQ2253 (an adenylate cyclase inhibitor) inhibits the cAMP pathway and increases PD-L1 expression of the LUAD cell lines H1299 and A549, and MYC regulation by these drugs was positively correlated with PD-L1 regulation, which verified the regulation of the cAMP/PDE4 pathway on MYC and PD-L1.…”

Shoshonitic pluton and an associated base-metal deposit in the Tarom–Hashtjin metallogenic zone, NW Iran: implication for tectono-magmatic evolution and metallogenic considerations... by M. Afshari (17554673)

“…The Hajseyran pluton, which is made up of syenite, monzonite, quartz-monzonite and granite, yields a zircon U–Pb age of 39.20 ± 0.56 Ma (for a quartz-monzonite sample) with shoshonitic features. …”

DataSheet1_Uptake of Ni(II), Eu(III) and Pu(III/IV) by Hardened Cement Paste in the Presence of Proxy Ligands for the Degradation of Polyacrylonitrile.pdf by P. G. Szabo (13908240)

“…A slight decrease in the distribution ratios for ⁶³Ni(II) and ²⁴²Pu(III/IV) is observed at [L]_tot > 10⁻² M, although the effect is less evident in the case of plutonium due to the dispersion of the data and the increase of the detection limits with increasing ligand concentrations. …”

FACS Analysis of TEC profile and quantification of TEC numbers in response to DKK1 mediated inhibition of Wnt signaling. by Masako Osada (253586)

“…CD45 magnetic beads were used to partially deplete CD45⁺ hematopoietic cells from the resulting single cell suspension, prior to staining with antibodies against CD45, MHCII, EpCAM, and CD80 together with UEA1 lectin. TetO-Dkk1 mice showed a dramatic decrease in the frequency of EpCAM⁺ MHCII⁺ CD45⁻ TECs (<b>A</b>, upper left) when compared with K5rtTA-ST controls (<b>A</b>, upper right panel). …”

VOR baseline and adaptation. by Giorgio Grasselli (217929)

“…<p>(A) Compensatory eye movements, aimed at minimizing retinal slip caused by visual and/or vestibular input, were used to test motor performance in L7-SK2 mice. …”

Data_Sheet_1_Modifications of the PI3K/Akt/mTOR axis during FeHV-1 infection in permissive cells.PDF by Gianmarco Ferrara (12673317)

“…In addition, we found an early phosphorylation of Akt, approximately 3 h after infection, without a concomitant decrease in constitutive Akt. This result suggests a possible role for this axis in viral entry. …”

Sample details and genome coverage (n = 1,409). by Mathieu Vanhove (3298326)

“…In the five-year study period, we observed a decrease in frequency of a mutation associated with artemisinin partner drug (piperaquine) resistance (<i>pfcrt</i> C350R) and limited co-occurence of <i>pfcrt</i> C350R with duplications of <i>plasmepsin 2/3</i>, an epistatic interaction associated with piperaquine resistance. …”

The human T-cell development is altered in HTLV-1-infected HIS Rag2^-/-γ_c^-/- mice. by Julien Villaudy (40472)

“…(<b>B</b>) Composite data from 20 HTLV-1-infected mice with a low PVL and 15 HTLV-1-infected mice with a high PVL showing a decrease in the frequency of the immature thymocytes (light grey) concomitant with an increase of that of the mature SP cells (black) in high PVL mice. …”

Data_Sheet_1_Isolation and identification of ligninolytic bacterium (Bacillus cereus) from buffalo (Bubalus bubalis) rumen and its effects on the fermentation quality, nutrient com... by Huimin Zhong (6847475)

“…The B. cereus AH7-7 additive treatments reduced the bacterial diversity and optimized the bacterial community compositions of silage, with an increase in the relative abundance of beneficial Lactobacillus and a decrease in the relative abundance of undesirable Pantoea and Erwinia. …”

DataSheet1_FGFC1 Selectively Inhibits Erlotinib-Resistant Non-Small Cell Lung Cancer via Elevation of ROS Mediated by the EGFR/PI3K/Akt/mTOR Pathway.docx by Shike Yan (777488)

“…Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have been used as a first-line treatment for patients harboring with EGFR mutations in advanced NSCLC. …”

Improvement of insulin sensitivity in diabetic and non diabetic patients with chronic hepatitis C treated with direct antiviral agents by Alessandro Gualerzi (6107468)

“…At the end of treatment, HCV-RNA quantification was below the detection threshold (HCV-RNA <12 UI/ml), for all patients enrolled. A significant decrease in glucose and insulin plasma concentrations was observed, leading to a significant reduction in Homeostasis Model Assessment (HOMA)-IR (from 3.42 [2.66–5.38] to 2.80 [1.78–3.95];p<0.001) and a corresponding increase in insulin sensitivity (ISI Belfiore from 0.49 [0.26–0.75] to 0.64 [0.42–0.91];p<0.001), despite a significant reduction in insulin secretion (EFP Stumvoll from 1363 [959–1730] to 1264 [976–1588];p = 0.027). …”

DataSheet_1_Comparison of Donepezil, Memantine, Melatonin, and Liuwei Dihuang Decoction on Behavioral and Immune Endocrine Responses of Aged Senescence-Accelerated Mouse Resistant... by Ju Zeng (3426107)

“…<p>Aging is a natural biological process associated with cognitive decline and neuroendocrine–immune system changes; the neuroendocrine–immune system plays crucial role in brain aging and neurodegeneration, and it is essential to discern beneficial attempts to delay the aging progress based on immunological aging. …”

Hyperbaric oxygen therapy and comprehensive orthopedic treatment for incomplete traumatic spinal cord injury on the Qinghai-Tibet Plateau: study protocol for an open-label randomiz... by Jun Ma (4058161)

“…<div>Background: Apoptosis secondary to ischemia and hypoxia is the main cause of spinal cord dysfunction. Because of the decrease in atmospheric pressure, patients living on the Qinghai-Tibet Plateau are in a hypoxic environment, which is very unfavorable for the recovery of spinal cord injury. …”