Data Sheet 1_Low CD46 expression on activated CD4+ T cells predict improved Th1 cell reactivity to calcitriol in majority of patients with allergic eosinophilic asthma and healthy... by Julie Stichova (19729855)

“…However, in both cohorts were individuals (HDs: 35/49, AEA: 40/58) who responded to calcitriol with a more pronounced regulatory response. The calcitriol-induced regulatory effect manifested by a stronger surface decrease of CD46 on activated CD4⁺ T cells (by 40% in HDs and by 26% in AEA), accompanied by a significant inhibition of IFN-γ and increased IL-10 production (by 31% in HDs and by 85% in AEA). …”

Primary and secondary outcomes. by Axel Cosmus Pyndt Diederichsen (3134508)

“…<div><p>Background</p><p>The Danish cardiovascular screening (DANCAVAS) trial, a nationwide trial designed to investigate the impact of cardiovascular screening in men, did not decrease all-cause mortality, an outcome decided by the investigators. …”

Budget impact of suzetrigine for the treatment of moderate-to-severe acute pain in Medicaid-insured adults by Kenna Garrison (22820311)

“…Use of suzetrigine led to a reduction in the number of patients using opioids and a corresponding decrease in the number of patients who experience OUD/opioid abuse or nausea/vomiting. …”

European study sites. by Graeme T. Swindles (7192745)

“…We also note that the highest values of aPAR are found when the water table is within 5–10 cm of the peatland surface. aPAR is generally low when water table depths are < 0 cm (standing water) or > 25 cm, which may relate to a decrease in plant productivity and increased decomposition losses, respectively. …”

Supplementary Material for: Physical Activity, Screen Time, and Sleep Duration of Children Aged 6–9 Years in 25 Countries: An Analysis within the WHO European Childhood Obesity Sur... by Whiting S. (9907584)

“…<b><i>Method:</i></b> The fourth COSI data collection round was conducted in 2015–2017, using a standardized protocol that included a family form completed by parents with specific questions about their children’s PA, screen time, and sleep duration. …”

Safety outcomes. by Axel Cosmus Pyndt Diederichsen (3134508)

“…<div><p>Background</p><p>The Danish cardiovascular screening (DANCAVAS) trial, a nationwide trial designed to investigate the impact of cardiovascular screening in men, did not decrease all-cause mortality, an outcome decided by the investigators. …”

Location of study sites. by Graeme T. Swindles (7192745)

“…We also note that the highest values of aPAR are found when the water table is within 5–10 cm of the peatland surface. aPAR is generally low when water table depths are < 0 cm (standing water) or > 25 cm, which may relate to a decrease in plant productivity and increased decomposition losses, respectively. …”

HeLa (Cilengitide treatment or MBCD treatment) PREM membrane images supporting "The structure and spontaneous curvature of clathrin lattices at the plasma membrane" by Kem Sochacki (10280270)

“…<br><div><br></div><div>HeLa cells were treated with drugs to remove cholesterol (methyl-β-cyclodextrin) or block the binding of aVB5 integrin (Cilengitide). Removing cholesterol caused an increase in flat clathrin while blocking integrins caused a decrease in flat clathrin. …”

Lack of decoration of <i>L</i>. <i>infantum</i> LEM 5700 parasites with lysosome-associated hydrolase cathepsin, hexose transporter GLUT8, and polypeptide transporter TAPL in macro... by Sandrine Cojean (274005)

“…<p><b>(A)</b> 3D-reconstruction surface rendering confocal micrograph showing the absence of decoration of fusiform-like and ellipsoidal parasite forms with GLUT8-positive patches in a Retro-2 (1 μM)-treated cell. …”

Transition-Metal Carbonyl Complexes of 2,5-Diferrocenyl-1-phenyl‑1<i>H</i>‑phosphole by Dominique Miesel (1533022)

“…However, the coordination of the dienic system in <b>9</b> results in a significantly decreased electronic communication of the Fc/Fc⁺ termini via the heterocyclic core.…”

COMMD1 mediates aggregation of ALS-associated SOD1 mutants. by Willianne I. M. Vonk (191330)

“…EV, SOD1 WT and mSOD1 D90A values were considered as 0 as these proteins do not form aggregates. * indicates significantly decrease in mSOD1 aggregation upon COMMD1 knock-down (* p<0.05, ** p<0.005, **** p<0.0001). n.s…”

Enrolment, randomisation, and follow-up. by Axel Cosmus Pyndt Diederichsen (3134508)

“…<div><p>Background</p><p>The Danish cardiovascular screening (DANCAVAS) trial, a nationwide trial designed to investigate the impact of cardiovascular screening in men, did not decrease all-cause mortality, an outcome decided by the investigators. …”

Cystic Fibrosis Transmembrane Conductance Regulator Attenuates Oxidative Stress-Induced Injury in Diabetic Retinopathy Rats by Hui Wang (30400)

“…</p> <p>CFTR can inhibit MAPK/NF-κB signaling pathway to ameliorate inflammatory response and oxidative stress-induced injury of DR rats, thereby reducing retinal cell apoptosis and playing a protective role in retina.</p>…”

DataSheet_2_Green tea extract suppresses airway inflammation via oxidative stress-driven MAPKs/MMP-9 signaling in asthmatic mice and human airway epithelial cells.zip by Jeong-Won Kim (18464976)

“…</p>Results<p>The GTE100 and GTE400 groups showed a decrease in airway hyperresponsiveness and the number of inflammatory cells in the bronchoalveolar lavage fluid (BALF) compared to the OVA group. …”

Image_1_Radiofrequency ablation plays double role in immunosuppression and activation of PBMCs in recurrent hepatocellular carcinoma.tif by Yang Zhao (39052)

“…The down-regulation of GZMB, GZMH, GZMK, and CD8A, which are involved in the cytotoxic function of T cells, was observed following RFA. …”

Image 2_The FGFR inhibitor Rogaratinib reduces microglia reactivity and synaptic loss in TBI.tif by Rida Rehman (11120838)

“…We have previously demonstrated that several members of the Fibroblast Growth Factor Receptor (FGFR) family are transiently phosporylated upon TBI; the availability for drug repurposing of FGFR inhibitors makes worthwhile the elucidation of the role of FGFR in the acute phases of the response to TBI and the effect of FGFR inhibition.</p>Methods<p>A closed, blunt, weight-drop mild TBI protocol was employed. …”

OTX fusions influence the activity of the <i>Ci-pitx cis</i>-regulatory element. by Maximilian Haeussler (86348)

“…<p>Co-electroporation of <i>Pitx</i> full length distal region (pDistal<i>Pitx</i>:lacZ, 5.3kb, containing D1), respectively with pSix3:Venus (control), with pSix3>OTX_HD::enR (dominant negative OTX) and pSix3>OTX_HD::VP16 (hyper-active OTX). (A) Side view of an embryo co-electroporated with pDistal<i>Pitx</i>:lacZ and pSix3:Venus. …”

Data_Sheet_1_Impacts of eutrophication on microbial community structure in sediment, seawater, and phyllosphere of seagrass ecosystems.docx by Wenchao Deng (2826569)

“…Introduction<p>Seagrass-associated microbial communities play a crucial role in the growth and health of seagrasses. …”

Image_1_Cytotoxicity of InP/ZnS Quantum Dots With Different Surface Functional Groups Toward Two Lung-Derived Cell Lines.TIF by Ting Chen (15205)

“…<p>Although InP/ZnS quantum dots (QDs) have emerged as a presumably less hazardous alternative to cadmium-based QDs, their toxicity has not been fully understood. …”

<i>In Vivo</i> Effects of Pichia Pastoris-Expressed Antimicrobial Peptide Hepcidin on the Community Composition and Metabolism Gut Microbiota of Rats by Lanfang Tian (3234513)

“…However their <i>in vivo</i> effects on gut microbiota and gut health of hosts remain unclear. Here we performed a safety study of hepcidin so that it can be used to reduce microbial contaminations in the food and feed. …”