Image_4_Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microsco... by Paula Dlugosz (6400175)

“…Details of this pathway are still not fully understood since the participating components are highly variable and create a complex mixture of interacting molecules. Reelin is proteolytically processed resulting in five different fragments some of which carrying the binding site for two different but highly homologous receptors, apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR). …”

Data_Sheet_1_In vitro Bactericidal Activities of Combination Antibiotic Therapies Against Carbapenem-Resistant Klebsiella pneumoniae With Different Carbapenemases and Sequence Type... by Jocelyn Qi-Min Teo (3148467)

“…Thus, combination therapy remains a suitable treatment option. We aimed to evaluate the in vitro bactericidal activity of various antibiotic combinations against CRKP with different carbapenemase genotypes and sequence types (STs). …”

Image_1_Fecal Microbiota Alterations Associated With Diarrhea-Predominant Irritable Bowel Syndrome.PDF by Xiaojun Zhuang (5556374)

“…Furthermore, rifaximin induced alterations of some special bacteria rather than affected the overall composition of microbiota in IBS-D patients. Meanwhile, a potential decrease in propanoate and butanoate metabolism was found in these IBS-D patients after rifaximin treatment. …”

Crystallographic Distinction between “Contact” and “Separated” Ion Pairs:  Structural Effects on Electronic/ESR Spectra of Alkali-Metal Nitrobenzenides by Milya G. Davlieva (2720230)

“…Such a loss in electronic conjugation (or reverse charge transfer) may be counterintuitive, but it is in agreement with the distribution of odd-electron spin electron density from the ESR data and with the hypsochromic shift of the characteristic absorption band in the electronic spectra. …”

Grid independence verification. by Ming Zhang (9736)

“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”

Table4_BMI1 fine-tunes gene repression and activation to safeguard undifferentiated spermatogonia fate.XLSX by Ruiqi Liu (3873832)

“…B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), one of spermatogonial stem cell markers, is a member of Polycomb repressive complex 1 (PRC1) and important to spermatogenesis. …”

Image_2_Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microsco... by Paula Dlugosz (6400175)

“…Details of this pathway are still not fully understood since the participating components are highly variable and create a complex mixture of interacting molecules. Reelin is proteolytically processed resulting in five different fragments some of which carrying the binding site for two different but highly homologous receptors, apolipoprotein E receptor 2 (ApoER2) and very low density lipoprotein receptor (VLDLR). …”

Effect of AcbC lesions on the execution of optimized behavior in the 8-arm FFT. by Chika Sato (556056)

“…<p>AcbC (n = 6 rats) or sham control lesions (n = 6) were made in well-trained rats. <b>A</b>: Averaged tip-approaching (TA) speeds before the last-reward collection (LRC) did not differ in well-trained AcbC-lesioned rats compared to sham controls (t = 0.67, <i>P</i>>0.05, unpaired <i>t</i>-test). …”

Lithogeochemical and sulfide trace-element systematics across the Permian–Triassic boundary, Perth Basin, Western Australia: constraints on the shallow marine environment during th... by E. Lounejeva (15450349)

“…Samples were collected from two oil exploration wells—Redback-2 and Hovea-3—spaced ∼20 km apart. In the two boreholes, a change in depositional facies (<i>i.e.</i> between the inertinite and sapropel) occurs below the Permian–Triassic boundary and records the transition from a marginal marine to a shelf environment. …”

Simulations derived from the PTO/TTFL model, including resilience and phase-locking. by Ximing Qin (247294)

“…<p>(A) PTO alone: In the absence of transcription and translation (i.e., for the in vitro reaction or for cells in DD), KaiC abundance is constant (red trace) and simulation of the PTO model indicates a sustained circadian oscillation in KaiC phosphorylation (black trace). …”

L2/3 pyramidal cell type composition and gene expression are selectively regulated during development. by Salwan Butrus (11682926)

“…Between P12 and P22, L2/3_A markers decrease in expression and increase in specificity, while L2/3_B markers increase in expression during development, driving cell type identity maturation (<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003176#pbio.3003176.s010" target="_blank">S1 Data</a>). …”

Enhanced Gemin3 knockdown in neuronal lineages leads to loss of adult viability and flight defects. by Rebecca Borg (504387)

“…Remarkably, we note that on pan-neuronal Gemin3 knockdown (via <i>n-syb</i>-GAL4 or <i>elav</i>-GAL4), we could also achieve a significant decrease in adult viability when culture temperature was raised to 29°C and, eventually, complete lethality on concomitant overexpression of Dicer-2. …”

Alterations in nuclear-encoded OXPHOS sub-units in trophoblasts upon hypoxia. by Philippe Vangrieken (5683748)

“…In cultured trophoblasts, 24 h hypoxia resulted in a significant decrease in autophagy-associated LC3BI and LC3BII protein levels while the ratio of LC3BI/LC3BII was significantly increased compared to the normoxic condition. …”

Nuclear Accumulation of dAtx2 Increases Its Toxicity <i>In Vivo</i> by Ismael Al-Ramahi (85012)

“…(H) Expression of dAtx2^NLS at similar levels as wild-type dAtx2 causes severe eye degeneration; the structure of the ommatidia is lost and interommatidial bristles are absent. In addition there is a strong decrease in eye size.</p><p>Genotypes: (A, A′) <i>UAS-CD8-GFP/UAS-dAtx2[<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030234#pgen-0030234-b004" target="_blank">4</a>]; ok107-GAL4/+</i>. …”

Comparison of expression and activity of ACE2 in cardiac tissue of the humanized mouse lines. by John N. Snouwaert (7901438)

“…Exchange of the mouse coding introns/exons for those of the human gene resulted in a major reduction in expression, with a 10-fold decrease in <i>ACE2</i> mRNA levels in the MP-ACE2 mice. …”

Connection between FabR and unsaturated membrane content in FFA producing <i>E. coli</i>. by Rebecca M. Lennen (275606)

“…In BTE-expressing cultures, a dramatic decrease in the number of intact cells was observed as a result of deletion of <i>fabR</i>. …”

<i>Bax</i> Deficiency Prevents Glaucomatous RGC Death by Richard T Libby (33317)

“…As expected, for <i>Bax</i>^+/+ retinas (C) from eyes with 95% or more optic nerve axon loss, there was a noticeable decrease in RGC layer cells (compare [C] to [A]). …”

Changes in connectivity strength and network metrics during resting state and task periods. by Thomas P. K. Breckel (455915)

“…Attentionally resilient subjects (blue) began to recover during the post-task phase and showed a decrease in functional connectivity in the direction of the pre-task values, whereas attentionally impaired subjects (red) showed further increases in global connectivity strength until the end of the measurement (see also <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074125#pone-0074125-g005" target="_blank">Figure 5</a> A). …”

Similarity diagrams for the evaluation of M1, M2 and ANN precision. by Thomas Schmid (428873)

“…Plotting these differences on the three axes of a three-dimensional coordinate system yielded a distribution with all data points falling onto a single plane within the three-dimensional space. …”

Data_Sheet_1_Empower Generations: Longitudinal Study for National Capacities in Life Sciences and Healthcare.xlsx by Asmaa Ali J. F. Althani (10650677)

“…As reported in 2012, a majority of the Qatari high-school students have shown a greater interest in business, technological, and administrative careers and a lower interest in healthcare. …”