Antitumor Activity and Induction of TP53-Dependent Apoptosis toward Ovarian Clear Cell Adenocarcinoma by the Dual PI3K/mTOR Inhibitor DS-7423 by Tomoko Kashiyama (162572)

“…In mouse xenograft models, DS-7423 suppressed the tumor growth of OCCA in a dose-dependent manner. Flow cytometry analysis revealed a decrease in S-phase cell populations in all the cell lines and an increase in sub-G1 cell populations following treatment with DS-7423 in six of the nine OCCA cell lines tested. …”

Table_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.xlsx by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

Image2_Neuronal nitric oxide synthase required for erythropoietin modulation of heart function in mice.pdf by Jeeyoung Lee (2638744)

“…</p><p>Results: ΔEPORE mice showed a decrease in the left ventricular outflow tract (LVOT) peak velocity, ejection fraction, and fractional shortening, showing that endogenous non-erythroid EPO response is protective for heart function. …”

Image_3_Comparison of long-term cardiovascular and renal outcomes between percutaneous coronary intervention and coronary artery bypass grafting in multi-vessel disease with chroni... by Woochan Kwon (13772311)

“…However, PCI-CR had a comparable 5-year death, MI, or stroke rate to CABG (HR: 0.86, 95% CI 0.54–1.38, p = 0.54).…”

Modulating the Coordination Environment of Cu-Embedded Mo<i>X</i>₂ (<i>X</i> = S, Se, and Te) Monolayers for Electrocatalytic Reduction of CO₂ to CH<sub>4</su... by Thamarainathan Doulassiramane (17382128)

“…Among the C1 products, CH₄ is selectively produced in all three SACs. Notably, there is a decrease in the limiting potential (<i>U</i>_<i>L</i>) when <i>X</i> changes from S to Te in Cu-Mo<i>X</i>₂. …”

DataSheet2_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.xlsx by Emily M. J. Fennell (6654536)

“…GO analysis of these data demonstrated additional similarity of response to ONC201 and TR-57, including a decrease in transcripts related to the mitochondrial inner membrane and matrix, cell cycle, and nucleus, and increases in other nuclear transcripts and transcripts related to metal-ion binding. …”

Acetate-Bridged Platinum(III) Complexes Derived from Cisplatin by Justin J. Wilson (1980262)

“…Density functional theory calculations suggest that the decrease in the ¹⁴N line width arises from a diminished electric field gradient at the ¹⁴N nuclei in the higher valent compounds. …”

DataSheet_1_Narrowing row spacing and adding inter-block promote the grain filling and flag leaf photosynthetic rate of wheat under enlarged drip tube spacing system.zip by Jianguo Jing (18767383)

“…The decline of NS22 (9.93%) was higher than that of NS44 (9.04%), and both cultivars also showed a greater decrease in grain weight and average grain-filling rate (AGFR) of inferior grains (NS22: 23.19%, 13.97%; NS44: 7.78%, 5.86%) than the superior grains (NS22: 10.60%, 8.33%; NS44: 4.89%, 4.62%). …”

Image4_Neuronal nitric oxide synthase required for erythropoietin modulation of heart function in mice.pdf by Jeeyoung Lee (2638744)

“…</p><p>Results: ΔEPORE mice showed a decrease in the left ventricular outflow tract (LVOT) peak velocity, ejection fraction, and fractional shortening, showing that endogenous non-erythroid EPO response is protective for heart function. …”

Neutralization of point mutants of B.1.351 and D614G spike-pseudotyped lentiviral particles by convalescent plasmas from B.1.351 and early 2020-infected individuals. by Allison J. Greaney (11046384)

“…<b>(B)</b> The fold-decrease in neutralization for samples shown in <b><a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010248#ppat.1010248.g005" target="_blank">Fig 5</a></b>, with the addition of previously measured neutralization by samples from 6 early 2020 convalescent individuals collected approximately 100 days post-symptom onset [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010248#ppat.1010248.ref038" target="_blank">38</a>]. …”

<i>Smad6</i> repression in senescence. by Atsushi Kaneda (198186)

“…The number of SA-β-gal(+) cells were significantly decreased in <i>Smad6</i>-introduced RasV12 cells compared with RasV12 (See also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002359#pgen.1002359.s008" target="_blank">Figure S8</a>). …”

Data Sheet 3_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”

Table_1_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

“…On D8 and D15, the patients presented a transition in the immunological profile. While, on D35, they already presented an opposite profile to D0, with an increase in NKT, CD3⁺ T, CD4⁺ T and Treg cells, along with CCL5, and a decrease in the levels of CXCL9, CXCL10 and IL-10, thus demonstrating that B-ALL patients present a complex and dynamic immune network during induction therapy. …”

Comparison of hemodynamic data. by Seung-Jae Joo (3620240)

“…After handgrip exercise, an increase in E_LVI (<i>P</i> = 0.021) and a decrease in VAC (<i>P</i> = 0.035) were observed specifically in men, with no corresponding changes noted in women. …”

S4 Fig - by Monica Sueiro-Olivares (5785451)

“…<p><b>(a)</b> Degradation rate of tert-Butyl hydroperoxide reflects H₂O₂ detoxifying activity. …”

Image1_Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer.jpg by Emily M. J. Fennell (6654536)

“…GO analysis of these data demonstrated additional similarity of response to ONC201 and TR-57, including a decrease in transcripts related to the mitochondrial inner membrane and matrix, cell cycle, and nucleus, and increases in other nuclear transcripts and transcripts related to metal-ion binding. …”

Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease by Viktor Martyanov (396510)

“…We assessed imaging biomarkers and performed gene expression profiling in a single-arm open-label clinical trial of tyrosine kinase inhibitor dasatinib in patients with SSc-associated interstitial lung disease (SSc-ILD).…”

Community health workers for non-communicable diseases prevention and control in developing countries: Evidence and implications by Gursimer Jeet (535149)

“…The duration of the studies ranged from mean follow up of 4 months for some risk factors to 19 months, and primary responsibilities of health workers included health promotion, treatment adherence and follow ups. Only a single trial reported all-cause mortality. The pooled effect computed indicated an increase in tobacco cessation (RR: 2.0, 95%CI: 1.11, 3.58, moderate-quality evidence) and a decrease in systolic blood pressure ((MD: -4.80, 95% CI: -8.12, -1.49, I² = 93%, very low-quality evidence), diastolic blood pressure ((MD: -2.88, 95% CI: -5.65, -0.10, I² = 96%, very low-quality evidence)) and blood sugar levels (glycated haemoglobin MD: -0.83%, 95%CI: -1.25,-0.41). …”

Comparison of echocardiographic data. by Seung-Jae Joo (3620240)

“…After handgrip exercise, an increase in E_LVI (<i>P</i> = 0.021) and a decrease in VAC (<i>P</i> = 0.035) were observed specifically in men, with no corresponding changes noted in women. …”

Table_1_Embryonic Thermal Manipulation Affects Ventilation, Metabolism, Thermal Control and Central Dopamine in Newly Hatched and Juvenile Chicks.DOCX by Aline C. G. Rocha (10984392)

“…Regarding 14d animals, the HT females showed a decrease in V._E and V.O₂ compared to CT and LT groups, while the HT males displayed a lower V.O₂ compared to CT males, but no changes in V.…”