Computational prediction of changes in brain metabolic fluxes during Parkinson’s disease from mRNA expression by Farahaniza Supandi (711503)

“…We predict for PD (1) decreases in glycolytic rate and oxygen consumption and an increase in lactate production in brain cortex that correspond with measurements (2) relative flux decreases in ATP synthesis, in the malate-aspartate shuttle and midway in the TCA cycle that are substantially larger than relative changes in glucose uptake in the substantia nigra, dopaminergic neurons and most other brain regions (3) shifts in redox shuttles between cytosol and mitochondria (4) in contrast to Alzheimer’s disease: little activation of the gamma-aminobutyric acid shunt pathway in compensation for decreased alpha-ketoglutarate dehydrogenase activity (5) in the globus pallidus internus, metabolic fluxes are increased, reflecting increased functional activity.…”

Position discrimination within the negative BOLD ROI of one representative subject's visual area V1. by David Bressler (25833)

“…A linear regression revealed a significant effect of Gabor separation on the spatial correlation (<i>f(x)</i> = 2.2<i>x</i>−0.08; F_(1,8) = 43.6, P<0.001).…”

Overview of the effect of assortative mating on nestling quality. by Morgan R. Harris (583422)

“…Pair similarity does not have a large effect on nestling quality in low competition sites, but in high competition sites, pair similarity significantly affects nestling quality. …”

Optimization of Acquisition time of ⁶⁸Ga-PSMA-Ligand PET/MRI in Patients with Local and Metastatic Prostate Cancer - Fig 5 by Susanne Lütje (3226503)

“…SUV_max and SUV_mean show a decreasing trend with increasing acquisition times, but remain stable at acquisition times of 4 min and later. …”

The qualitative results from Fig 2 are preserved with increased carrying capacity, with no constitutive growth (λ₀). by Alexander S. Moffett (8250291)

“…As with the results in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010292#pcbi.1010292.g002" target="_blank">Fig 2</a>, QS decreases cheater fixation probability but also decreases mean extinction time as compared with AO. …”

Higher initial densities alter the most competitive phenotypes. by Tong Liang (667312)

“…A birth rate of <i>b</i>₅ = 5 is used in the mean-field model so that 〈<i>γ</i>₄(<i>t</i>)〉 converges to 10 at low densities.…”

Activity levels over 24 in juvenile and adult mdx and control mice. by Hannah G. Radley-Crabb (524281)

Module assignment changes and spatial organisation. by Michael Mackay (411250)

“…<b>d-e)</b> show the mean and standard deviation of the number of assignment changes over a whole simulation as a function of connection strength for a range of η. …”

Data_Sheet_1_Spatial Patterns of Particles and Plankton in the Warming Arctic Fjord (Isfjorden, West Spitsbergen) in Seven Consecutive Mid-Summers (2013–2019).docx by Marlena Szeligowska (9133580)

“…<p>The restructuring of planktonic communities toward an increasing share of small individuals is not only expected, but also already observed consequence of warming in the rapidly changing Arctic. Here, we demonstrate a simultaneous study on the nano-, micro- and meso plankton (divided into small and large), and corresponding size fractions of particles along a hydrographical gradient in the Isfjorden – the largest Spitsbergen fjord system. …”

Alteration of the trafficking of the insulin-sensitive GLUTs in the diabetic atria. by Zahra Maria (840566)

“…<p><b>Decreased atrial A) GLUT4 and B) GLUT8 content during type 1 diabetes</b> (T1Dx). …”

DataSheet_1_SIRT3 alleviates imiquimod-induced psoriatic dermatitis through deacetylation of XBP1s and modulation of TLR7/8 inducing IL-23 production in macrophages.pdf by Meiliang Guo (11871101)

“…Although it has been established that Sirtuin 3 (SIRT3) mediates the inflammatory process, the underlying mechanisms remain largely unclear. Herein, we substantiated that the inhibition or deletion of SIRT3 increased the acetylation level of spliced form of X-box binding protein 1 (XPB1s), enhancing its transcriptional activity and IL-23a production. …”

Data_Sheet_1_Sex-specific changes in autosomal methylation rate in ageing common terns.PDF by Britta S. Meyer (3362387)

“…We collected blood at 1-, 3- and/or 4-year intervals, extracted DNA from the erythrocytes and estimated autosomal DNA methylation by mapping Reduced Representative Bisulfite Sequencing reads to a de novo assembled reference genome. We found autosomal methylation levels to decrease with age within females, but not males, and no evidence for selective (dis)appearance of birds of either sex in relation to their methylation level. …”

Cep192 Controls the Balance of Centrosome and Non-Centrosomal Microtubules during Interphase by Brian P. O’Rourke (590103)

“…The depletion of Cep192 results in a significant decrease in the level of centrosome-associated gamma-tubulin, likely explaining its impact on centrosome microtubule nucleation. …”

Effects of Water and Nitrogen Addition on Species Turnover in Temperate Grasslands in Northern China by Zhuwen Xu (154136)

“…However, temporal patterns of species turnover underlying diversity changes in response to changing precipitation regimes and atmospheric N deposition have received inadequate attention. We carried out a manipulation experiment in a steppe and an old-field in North China from 2005 to 2009, to test the hypothesis that water addition enhances plant species richness through increase in the rate of species gain and decrease in the rate of species loss, while N addition has opposite effects on species changes. …”

Table_5_Crosstalk of DNA Methylation Triggered by Pathogen in Poplars With Different Resistances.XLSX by Dandan Xiao (11880449)

“…The results revealed that DNA methylation changed dynamically in poplars during the infection process with a remarkable decrease seen in the DNA methylation ratio. …”

Image_5_Crosstalk of DNA Methylation Triggered by Pathogen in Poplars With Different Resistances.JPEG by Dandan Xiao (11880449)

“…The results revealed that DNA methylation changed dynamically in poplars during the infection process with a remarkable decrease seen in the DNA methylation ratio. …”

Image_7_Crosstalk of DNA Methylation Triggered by Pathogen in Poplars With Different Resistances.JPEG by Dandan Xiao (11880449)

“…The results revealed that DNA methylation changed dynamically in poplars during the infection process with a remarkable decrease seen in the DNA methylation ratio. …”

Table_8_Crosstalk of DNA Methylation Triggered by Pathogen in Poplars With Different Resistances.DOCX by Dandan Xiao (11880449)

“…The results revealed that DNA methylation changed dynamically in poplars during the infection process with a remarkable decrease seen in the DNA methylation ratio. …”

DataSheet1_Impact of wastewater reuse on contaminants of emerging concern in an effluent-dominated river.pdf by Jordyn M. Wolfand (11936249)

“…A water quality module was added to a calibrated hydrologic model of the system and parametrized with observed water quality monitoring data in EPA SWMM. …”

Table_2_Crosstalk of DNA Methylation Triggered by Pathogen in Poplars With Different Resistances.DOCX by Dandan Xiao (11880449)

“…The results revealed that DNA methylation changed dynamically in poplars during the infection process with a remarkable decrease seen in the DNA methylation ratio. …”