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60541
Immunohistochemical (IHC) analysis of the aortae of TIC-, CLO-, and CTL-treated animals.
Published 2019“…<p>Abbreviations: CTL, control; CLO, clopidogrel; TIC, ticagrelor; A.U., arbitrary units; F4/80, F4/80 antigen also known as adhesion G protein-coupled receptor E1 (EMR1); MΦ, macrophages; α-SMA, alpha smooth muscle cell actin; VSMC, vascular smooth muscle cells; S100A4, S100 calcium-binding protein A4; FB, fibroblasts; TGFβ1, transforming growth factor β1; 4-HNE, 4-hydroxynonenal; P-IRE1, phosphorylated inositol-requiring enzyme 1; Size bars, 300 μm; N = 13–18, 6–7, 13–18, 6–7, 11–17, and 6–7 per group for (A), (B), (C), (D), (E), and (F), respectively; Error bars, means ± SD, statistical analyses performed using ANOVA with Fisher’s multiple comparison; NS, not statistically significant; *, P < 0.05; **, P < 0.01. …”
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60542
Dynamics of chromatin accessibility and gene expression are correlated during metamorphosis.
Published 2019“…(B) Dynamic open chromatin peaks were organized into 18 k-means clusters, displayed as a heatmap representing the fraction of the maximum FAIRE rpkm value. …”
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60543
Soil analyses along the stress gradient.
Published 2017“…<p>Soil analyses (means ±SE) of the mesocosms having different intensities of stress (low stress: SL, medium stress: SM, and high stress: SH) in 2009 (a) and 2014 (b). …”
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60544
Responses of the picoprasinophyte <i>Micromonas commoda</i> to light and ultraviolet stress
Published 2017“…However, expression of these genes decreased in HL+UV, likely as a photoprotective mechanism. …”
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60545
Kinetics of Ldt<sub>fm</sub> inactivation by imipenem, ceftriaxone, and ampicillin.
Published 2013“…Regression analysis was performed with equation F<sub>t</sub> = F<sub>eq</sub>+ΔF e<sup>−<i>k</i>obst</sup> in which F<sub>eq</sub> and F<sub>t</sub> are the fluorescence intensities at equilibrium and at time t, respectively, ΔF is the difference between fluorescence intensity at time = 0 and at equilibrium, t is time, and <i>k</i><sub>obs</sub> is a constant. The resulting rate constants (<i>k</i><sub>obs</sub>) increased linearly with the drug concentration (E) and the slope provided an estimate of the efficiency of enzyme acylation (F).…”
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60546
Disappearing Scales in Carps: Re-Visiting Kirpichnikov's Model on the Genetics of Scale Pattern Formation
Published 2013“…We observed phenotypic changes which were not restricted to nudes, as described by Kirpichnikov, but were also present in mirrors (and presumably in linears as well; not analyzed in detail here). We propose that the gradation of phenotypes observed within the scattered group is caused by a gradually decreasing level of signaling (a dose-dependent effect) probably due to a concerted action of multiple pathways involved in scale formation.…”
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60547
Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of V...
Published 2015“…Vegetable oils represent an attractive target for intervention, as they largely determine the intake of dietary fats. Furthermore, besides potential health effects conferred by the type of fatty acids in a vegetable oil, other minor components (e.g. phytochemicals) may also have health benefits. …”
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60548
BALB/C nude mouse subcutaneous transplantation tumor experiment and immunohistochemistry of the transplanted tumors.
Published 2018“…<i>OVOS2</i> downregulation significantly decreased tumor growth and one tumor spontaneously regressed in the A375/<i>OVOS2</i>-shRNA group. …”
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60549
Placental features associated with stillbirth, fetal growth restriction and reduced fetal movements.
Published 2015“…Key: ↑ = increased, ↓ = decreased, ↔ = unaltered, N/A = not applicable</p><p>* largely inferred from studies of maternal or cord blood or explant conditioned medium.…”
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60550
Effect of surfactant and electron treatment on the electrical and thermal conductivity as well as thermal and mechanical properties of ehylene vinyl acetate/expanded graphite compo...
Published 2015“…The thermal conductivity linearly increased with EG content, and this increase was more pronounced in the case of SDS-EG, but decreased after EB irradiation. …”
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60551
Dry matter intake and ruminal fermentation parameters in goats fed sugarcane in replacement of corn silage
Published 2022“…However, the acetate:propionate ratio linearly decreased with increased sugarcane content. …”
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60552
The average time cost and accuracy of the assessed secondary structure prediction methods as the sequence homology of the target dataset reduces.
Published 2020“…The lowest sequence identity was 25% because when a lower identity such as 20% was applied, the number of sequences remaining in the target dataset would be far smaller than the 5 million safety zone (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.g002" target="_blank">Fig 2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0235153#pone.0235153.s016" target="_blank">S6 Table</a>) and then cause unreasonable decreases of the accuracy. …”
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60553
SMAD2/3 and TGF-ß1 suppress expression from the megalin promoter.
Published 2019“…Cells expressing the megalin promoter construct showed a 50% decreased in luciferase activity when the SMAD transcription factors were overexpressed. …”
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60554
Interleukin- 6 and micoRNA –mir 21- related network.
Published 2008“…Red (and pink) means significantly increased gene expression and blue decreased. …”
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60555
Trade-off between Processivity and Hydrolytic Velocity of Cellobiohydrolases at the Surface of Crystalline Cellulose
Published 2014“…We found that high moving velocity of enzyme molecules on the surface is associated with a high dissociation rate constant from the substrate, which means weak interaction between enzyme and substrate. …”
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60556
Trade-off between Processivity and Hydrolytic Velocity of Cellobiohydrolases at the Surface of Crystalline Cellulose
Published 2014“…We found that high moving velocity of enzyme molecules on the surface is associated with a high dissociation rate constant from the substrate, which means weak interaction between enzyme and substrate. …”
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60557
Trade-off between Processivity and Hydrolytic Velocity of Cellobiohydrolases at the Surface of Crystalline Cellulose
Published 2014“…We found that high moving velocity of enzyme molecules on the surface is associated with a high dissociation rate constant from the substrate, which means weak interaction between enzyme and substrate. …”
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60558
Lysis of classical O395 when grown individually in monocultures or in cocultures with El Tor N16961 Δ<i>dns</i>Δ<i>xds</i> (DNase<sup>−</sup>).
Published 2013“…<p>CFU of O395 and O395 DNA in the supernatant (sup) were estimated in monocultures (a) and cocultures (b). DNA released into the supernatant when CFU of O395 in individual cultures decreased approximately six fold and that in cocultures decreased >10000 fold is indicated. …”
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60559
<i>In vitro</i> proliferation assessment.
Published 2013“…Globally no differences are noted between all groups, a light statistically significant decreased in EdU positive cells is observed between control and treated cells incubated in High Medium. …”
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60560
Average cell length affects nematic ordering in open-walled microfluidic trap simulations.
Published 2021“…Circles and error bars represent means and standard deviations, respectively, for a single, representative simulation at each division length. …”