Gadolinium-free Magnetic Resonance Imaging of the Liver via an Oatp1-Targeted Manganese(III) Porphyrin by Nivin N. Nyström (13118188)

“…Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their continued utility highly contentious, but the liver-specific GBCA Gd­(III) ethoxybenzyl-diethylene triamine pentaacetic acid (Gd­(III)-EOB-DTPA) remains in use because it provides unique diagnostic information that could not be obtained by any other means. To address the need for an alternate liver-specific MRI probe, we synthesized Mn­(III) 20-(4-ethoxyphenyl) porphyrin-5,10,15-tricarboxylate (Mn­(III)­TriCP-PhOEt), which exhibited significantly higher <i>r</i>₁ relaxivity than Gd­(III)-EOB-DTPA in vitro, while also targeting hepatocyte-specific organic anion-transporting polypeptide 1 (Oatp1) channels as a marker of viability. …”

Variability of Coastal and Ocean Water Temperature in the Upper 700 m along the Western Iberian Peninsula from 1975 to 2006 by Fran Santos (113729)

“…The analysis was carried out by means of the Simple Ocean Data Assimilation (SODA). …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. …”

Comparison of SPTAN1 in MLH1-proficient vs. MLH1-deficient CRCs. by Anne Ackermann (6443975)

“…SPTAN1 was significantly increased in MLH1-proficient tumors compared with the normal mucosa, while MLH1-deficient tumors showed a clear trend of decreased SPTAN1 levels compared with surrounding normal tissue. …”

Enforced expression of Mfn2 and DRP1 relieves Vpr-induced apoptosis. by Chih-Yang Huang (54970)

“…<b>D,</b> Overexpression of Mfn2, DRP1, and Mfn2/DRP1 reduced Vpr-induced apoptosis. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033657#s2" target="_blank">Results</a> are the means ± S.D. of three independent experiments. …”

<b>Pirani Gauge: Function, Calibration, and Use in Pharmaceutical Freeze-Drying</b> by Geoff Smith (6064268)

“…During freeze-drying, this results in <b>higher readings while ice is sublimating</b>, and the signal decreases as sublimation slows. Importantly, the <b>end of ice sublimation can occur during (but often around the midpoint) of the step-down in the Pirani signal</b>, meaning the gauge alone cannot precisely identify the sublimation endpoint. …”

Genome-Wide Patterns of Gene Expression during Aging in the African Malaria Vector <em>Anopheles gambiae</em> by Mei-Hui Wang (203053)

“…<div><p>The primary means of reducing malaria transmission is through reduction in longevity in days of the adult female stage of the <em>Anopheles</em> vector. …”

T cell survival is regulated by DUSP5. by Raman G. Kutty (3390200)

“…Plots are means with error bars ±SEM. Comparisons were made using a two-tailed t-test, *: p<0.05, **: p<0.01 ***: p<0.005.…”

Differences in lipid mediators between sPTB and FTB in obese and underweight groups. by Kamil Borkowski (629694)

“…Saturated and monounsaturated fatty acids were not measured in this assay and are indicated only to visualize parent fatty acids for measured oxylipins and endocannabinoids. Means of individual metabolites and corresponding p-values are provided in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0239115#pone.0239115.s003" target="_blank">S2 Table</a>.…”

Cardiolipin is required to maintain protein import upon mtUPR. by Daniel Poveda-Huertes (4609723)

“…(D) Quantification of imports from (A)-(C). Compared is the longest import time point from <i>crd1Δmas1</i>^<i>ts</i> in comparison to <i>crd1Δ</i>. n = 3, data represent means ± SEM. …”

Assessment of B cell development in the BM of transgenic mice. by Ying Xing (278605)

“…<p>BM cells from the indicated mouse strains were stained with anti-B220, anti-CD43, and anti-IgM, and were analyzed by FACS. (A) The gates in panels represent Hardy fractions A-D (proB to preBII), and can be divided into fraction A-C (proB to preBI, upper rectangle) and fraction D (preBII, lower rectangle) by the expression of CD43. …”

Data Base COVID proyect by Carolina Cubillos Zapata (15345850)

“…<p> COVID-19 has emerged as a devastating disease in the last 2 years. Many authors appointed to the importance of kallikrein-kinin system (KKS) in COVID-19 pathophysiology as it is involved in inflammation, vascular homeostasis, and coagulation. …”

Influence of NOD on TNF-α mediated NFκB activation. by Maximilia C. Hottenrott (452847)

“…Note that in the condition of TNF-α+NOD phosphorylation of p65 at Ser276 is not detectable in the nuclear extracts and that expression of total p65 in both nuclear and cytoplasmic extracts is decreased. The results of a representative experiment are shown. …”

Effects of 20(S)-Rg3 on Snail expression and E-cadherin promoter activity. by Ting Liu (45625)

“…<p>(A) SKOV3 cells were cultured in normal condition for 24 h, and then cultured in 21% O₂ (normoxia) or 1% O₂ (hypoxia) or 1% O₂ and 80 µg/ml 20(S)-Rg3 (hypoxia+20(S)-Rg3) for another 24 h. …”

Polyampholyte−Surfactant Film Tuning in Reverse Microemulsions by Mabya Fechner (1943278)

“…Additionally, the required amount of surfactant to establish a clear w/o microemulsion depends on the pH value, which means the hydrophobicity of the copolymers. …”

Pathogenicity testing and transcriptome analysis. by Brett Hale (16510142)

“…<p>(<b>a</b>) Disease development in Race 25- (top) and Race 1-treated (bottom) hypocotyls at seven days post-infection. …”

The <i>ENT2</i> knockout effects on CRC proliferation and survival. by Safaa M. Naes (22075434)

“…Data are presented as means ± SD and expressed as % relative to control cells. * indicates a significant difference between NTC vs. …”

HC11 cells increase Pthlh gene expression and activity via cAMP with increases in intracellular 5HT. by Celeste M. Sheftel (9557588)

“…</b> Monoamine oxidase-A (MAO-A) gene expression is significantly upregulated in 5HTP treatment. …”

Mu opioid agonist-induced [³⁵S]-GTPγS binding is comparable on spinal cord membrane preparation from mu-cKO and mu^fl mice. by Raphaël Weibel (458030)

“…[³⁵S]-GTPγS binding was absent on spinal cord membranes from mu-KO mice, and was decreased by half with a 50%-50% mix of membranes from mu^fl and mu-KO animals, containing half mu receptors as compared to mu^fl membranes, indicating that this assay allows to detect reduced receptor expression. …”

Immunolocalization and Western blot analysis of liver GK. by Magdiel Salgado (553127)

“…Hypoglycemia (A–C), normoglycemia (D–F) and hyperglycemia (G–I). …”