Electromobility shift assay (EMSA) of nuclear extracts from CD4 T cells (preincubated with anti-CD4 mAbs or stimulated with PMA/ionomycin) for AP-1 and NF-κB by Dirk Pohlers (54711)

“…Quantification of the bands of all three experiments is shown below (means ± SEM). All three anti-CD4 mAbs slightly decreased the AP-1 activity, and RIB5/2 induced a profound, significant increase of NF-κB activity. ≤ 0.05 in comparison with the isotype control, ≤ 0.05 in comparison with W3/25, ≤ 0.05 in comparison with OX35, ≤ 0.05 in comparison with RIB5/2.…”

Comparisons of the active components in four unripe raspberry extracts and their activites by Jing YANG (7501766)

“…Moreover, 11 typical polyphenols were quantified using a HPLC-MS analysis showed that HTHP treatments were conducive to releasing more (+)-catechin, (−)-epicatechin, proanthocyanidin B1 and ellagic acid, reaching ~70% ‒1,100%, but decreased the rutin, quercetin-3-O-glucuronide, kaempferol-3-O-rutinoside and kaempferol-3-O-glucoside levels by ~10% –20%. …”

RenTg mice are hypertensive and develop chronic kidney disease progressively with the age. by Anne-Cecile Huby (291994)

“…<p>Systolic blood pressure was highly increased in RenTg mice since the age of 3 months as compared to aged matched WT controls (A). Urinary excretion of albumin progressively increased with age to reach at 12 months highly elevated values in RenTg mice (B) whereas GFR significantly decreased (C). …”

Comparisons of the active components in four unripe raspberry extracts and their activites by Jing YANG (7501766)

“…Moreover, 11 typical polyphenols were quantified using a HPLC-MS analysis showed that HTHP treatments were conducive to releasing more (+)-catechin, (−)-epicatechin, proanthocyanidin B1 and ellagic acid, reaching ~70% ‒1,100%, but decreased the rutin, quercetin-3-O-glucuronide, kaempferol-3-O-rutinoside and kaempferol-3-O-glucoside levels by ~10% –20%. …”

Induction of Cell Death by Ternary Copper(II) Complexes of l-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity by Sethu Ramakrishnan (2081944)

“…In contrast with the increase in relative viscosities of DNA bound to <b>2</b>−<b>4</b>, the viscosity of DNA bound to <b>1</b> decreases, indicating the shortening of the DNA chain length by means of the formation of kinks or bends. …”

Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation by Tore K. Danielsen (5938208)

“…The essential role of catecholaminergic effects on ventricular cardiomyocytes in this situation is well documented, but the importance of heart rate <i>per se</i> for arrhythmia initiation in CPVT1 is largely unexplored.</p><p>Methods and results</p><p>Sixteen CPVT1 patients performed a bicycle stress-test. …”

Data_Sheet_1_Enhanced Fluorescence of N-Acetyl-β-D-Glucosaminidase Activity by ZnO Quantum Dots for Early Stage Mastitis Evaluation.docx by Narsingh R. Nirala (4588363)

“…<p>Recurrent mastitis events are the major cause of annual revenue losses in the dairy sector resulting in decreased milk yield, escalading treatment costs and increased health risk of the entire herd. …”

Table1_Trends in the contributions of atopic family history to pediatric food sensitization and allergy.docx by Heping Fang (14229968)

“…Subgroup analysis showed the FS rate in FA group decreased significantly (37/39 to 44/62, P = 0.003). …”

Image_1_Changes in Soil Chemistry After 17 Years in Urban and Rural Forest Patches.pdf by Ian Yesilonis (7482125)

“…Overall, means of Ca concentration, pH, and C:N ratios significantly changed from 2001 to 2018. …”

Phenotypic characterization of <i>CsIVP</i>-RNAi transgenic plants. by Shuangshuang Yan (798064)

“…<p>(A) Plant morphology of WT and <i>CsIVP-</i>RNAi lines R5, R3, and R2. …”

BAF155 and Pax6 synergistically control neurogenesis in embryonic OE. by Christina Bachmann (3111933)

“…<p>(A) Immunoprecipitation of BAF155 from cultured OE NSCs and Western blot analysis using an anti-Pax6 antibody demonstrated that BAF155 interacts with Pax6 in OE cells. …”

Characterization of the dehydrogenase-reductase DHRS2 and itsinvolvement in histone deacetylase inhibition in urological malignancies by Daniel Nettersheim (2866097)

“…</p><p dir="ltr">Methods: </p><p dir="ltr">DHRS2 expression was evaluated on mRNA- and protein-level upon treatment with HDACi by means of qRT-PCR and western blot analyses, respectively. …”

Inhibiting IDO-1 with INCB24360 reduced the M1-like macrophage proportion in the RAW264.7 cells induced by IFN-γ. by Rong Ji (1496803)

“…<p><b>(A)</b> The typical morphology of RAW264.7 cells after treatment with IFN-γ, IFN-γ+1-MT and IFN-γ + INCB24360. …”

Data_Sheet_1_Muscle Belly Gearing Positively Affects the Force–Velocity and Power–Velocity Relationships During Explosive Dynamic Contractions.pdf by Andrea Monte (6439652)

“…During EDC, fascicle velocity, belly velocity, belly gearing, and knee extensors torque data were analysed from 0 to 150 ms after torque onset; the fascicles and belly F–V and P–V potentials were thus calculated for each EDC. Absolute torque decreased as a function of angular acceleration (from 80 to 71 Nm, for EDC at 1000 and 4000°.s^–1, respectively), whereas fascicle velocity and belly velocity increased with angular acceleration (P < 0.001). …”

Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway by Deepak Kumar (63095)

“…</p><p>Conclusions</p><p>Thus, these findings prove the dual ability of AG–4 to induce apoptosis and autophagy which provide a new perspective to it as a potential molecule targeting PCD for future cancer therapeutics.…”

Protein levels of COX-2 in cAT-MSC derived EVs and the effect of DFO preconditioned EV in DH82. by Su-Min Park (11185660)

“…<p><b>(a)</b> COX-2 level was increased in EVs derived from cAT-MSC^DFO (EV^DFO). …”

C1GALT1 regulates lung metastasis of HCC cells in NOD/SCID mice. by Chiung-Hui Liu (291005)

“…<p>(<i>a</i>) Stable overexpression and knockdown of C1GALT1 in HCC cells. …”

Data Sheet 1_Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors.docx by Monika Marko (7926311)

“…Objective<p>The study is based on a respiratory educational program aimed at training medical personnel to use inhalers correctly and educating patients on improving their inhalation skills.…”

Expression profile of cell cycle-related genes in the PSG during silkworm development. by Wenliang Qian (639395)

“…<p>(<b>A</b>) <i>Fzr</i> was continuously expressed in the PSG during the fourth larval instar, while <i>CycB</i> was not expressed. …”

Effects of U0126, T0070907, and Pioglitazone hydrochloride (Pio) on NO production in LPS-stimulated RAW264.7 macrophages. by Xiang Li (114679)

“…ERK1/2 phosphorylation antagonist U0126 significantly inhibited NO production (**<i>p</i><0.01 vs. LPS treated alone) (A and D). PPARγ phosphorylation inhibitor T0070907 strongly suppressed NO release (**<i>p</i><0.01 vs. model) (C), while PPARγ agonist Pio decreased NO secretion (**<i>p</i><0.01 vs. model) (B). …”