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29481
Table_1_HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.pdf
Published 2020“…Cytokine and gene expression analyses confirmed that IFNγ-treated macrophages consistently develop a cytokine response after LPS repeated challenge, but pretreatment with HDAC3i or HDAC3 siRNA reinstates a state of tolerance reflected by general suppression of tolerizable genes, possibly through decreasing TLRs expression, and particularly TLR4/CD14. …”
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29482
Table_2_HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.xlsx
Published 2020“…Cytokine and gene expression analyses confirmed that IFNγ-treated macrophages consistently develop a cytokine response after LPS repeated challenge, but pretreatment with HDAC3i or HDAC3 siRNA reinstates a state of tolerance reflected by general suppression of tolerizable genes, possibly through decreasing TLRs expression, and particularly TLR4/CD14. …”
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29483
Table_3_HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.xlsx
Published 2020“…Cytokine and gene expression analyses confirmed that IFNγ-treated macrophages consistently develop a cytokine response after LPS repeated challenge, but pretreatment with HDAC3i or HDAC3 siRNA reinstates a state of tolerance reflected by general suppression of tolerizable genes, possibly through decreasing TLRs expression, and particularly TLR4/CD14. …”
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29484
DataSheet_2_HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.pdf
Published 2020“…Cytokine and gene expression analyses confirmed that IFNγ-treated macrophages consistently develop a cytokine response after LPS repeated challenge, but pretreatment with HDAC3i or HDAC3 siRNA reinstates a state of tolerance reflected by general suppression of tolerizable genes, possibly through decreasing TLRs expression, and particularly TLR4/CD14. …”
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29485
Western blot analysis of hippocalcin in glutamate-exposed neurons.
Published 2024“…<p>Hippocalcin expression decreases in hippocalcin siRNA-transfected cells. Western blot analysis of hippocalcin (A) in glutamate (Glu)- and/or epigallocatechin gallate (EGCG)-treated hippocampal neuronal cells (HT22) in non- and hippocalcin siRNA-transfected cells. …”
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29486
Reduced expression of Np9 in NCCIT teratocarcinoma cells increases sensitivity to chemical stress.
Published 2019“…Reduced expression of Np9 resulted in increased sensitivity to bleomycin or cisplatin treatment with decreased viability of NCCIT cells. T bars denote the standard deviations of the means; P values were determined using student t-test analysis. ns not significant, *<i>P</i><0.05, **<i>P</i><0.001, ***<i>P</i><0.0001.…”
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29487
Expression change of olfactory sensory system genes in sex determination gene mutants.
Published 2020“…<p>(A) Relative mRNA expression levels of <i>BmPBP1</i>, <i>BmPBP2</i>, <i>BmPBP3</i>, <i>BmOR1</i>, <i>BmOR2</i>, and <i>BmOR3</i> in WT and mutant males. …”
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29488
Ethynyl deoxyuridine dose titration for labeling lateral ventricular wall cells in adult mouse brain
Published 2024“…<p dir="ltr">Ethynyl deoxyuridine (EdU) can be toxic to cells (<a href="https://doi.org/10.1073/pnas.1219563110" target="_blank">https://doi.org/10.1073/pnas.1219563110</a>). …”
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29489
Comparison of CBVs in different brain regions of WT and Katnal2-KO mice.
Published 2024“…<p>(A) Comparisons of cerebral blood volumes (CBVs) in WT and Katnal2-KO brains, as shown by the extents of decreases in fMRI signals induced by hypoxic nitrogen stimulus in different brain regions (left, relative CBVs) and the KO values normalized to WT values (right, %WT). …”
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29490
STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I
Published 2019“…Moreover, we observed that STYK1 directly binds to the PtdIns3K-C1 complex as a homodimer. The binding with this complex was promoted by Tyr191 phosphorylation, by means of which the kinase activity of STYK1 was elevated. …”
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29491
<i>Fzr</i> mutation blocks endoreplication in PSG cells.
Published 2023“…<p>(<b>A</b>) EdU staining in silkworm PSG cells. The PSG cells of the control could be strongly stained with EdU, but no EdU signal was detected in PSG cells with <i>Fzr</i> mutation. …”
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29492
Endothelial dysfunction in the WTD-GS (+) group is independent of metabolic parameters.
Published 2022“…<p>A: Body weight curve over the duration of feeding and administration. § <i>P</i> < 0.001 comparison between diet groups, two-way repeated-measures ANOVA. …”
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29493
Study on the expression of mRNA related to biofilm formation of <i>C. albicans</i> by CSR extract (100 μg/mL).
Published 2025“…<p><b>(A)</b> Differentially expressed genes (DEGs) analysis performed on transcriptomic samples. …”
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29494
Epidemiological characterization of reported cases of brucellosis in cattle in the western region of the state of Santa Catarina, Brazil
Published 2021“…The prevalence of the disease was evaluated in cattle and herds by means of temporal trend analysis and spatial distribution. …”
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29495
Acute response of refeeding in tambaqui submitted to long-term fasting
Published 2022“…<div><p>ABSTRACT This study aimed evaluate energetic mobilization in tambaqui submitted to fasting, after a one-day refeeding. 120 tambaqui juveniles were distributed in 12 310L polyethylene boxes. …”
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29496
Table_1_Inflammation produced by senescent osteocytes mediates age-related bone loss.docx
Published 2023“…</p>Methods<p>We collected bone tissues from children, middle-aged individuals, and elderly people for protein sequencing and compared the three groups of proteins pairwise, and the differentially expressed proteins (DEPs) in each group were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). K-means cluster analysis was then used to screen out proteins that continuously increased/decreased with age. …”
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29497
Lack of ComDE and/or AliB results in an attenuated inflammatory response to pneumococcal infection of the CSF.
Published 2019“…<b>(A)</b> Mice infected with the single or double mutants showed significant decreases in CSF pleocytosis, as compared to D39 infected mice. …”
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29498
Table_3_Inflammation produced by senescent osteocytes mediates age-related bone loss.xlsx
Published 2023“…</p>Methods<p>We collected bone tissues from children, middle-aged individuals, and elderly people for protein sequencing and compared the three groups of proteins pairwise, and the differentially expressed proteins (DEPs) in each group were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). K-means cluster analysis was then used to screen out proteins that continuously increased/decreased with age. …”
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29499
Data_Sheet_1_Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the...
Published 2019“…<p>Derived from arachidonic acid (AA), the endogenous cannabinoid (eCB) 2-arachidonoyl glycerol (2-AG) is a substrate for α/β hydrolase domain-12 (ABHD12). …”
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29500
Silencing of <i>NbUBL5s</i> facilitates the infection of RSV.
Published 2020“…<p>A. Silencing of <i>NbUBL5s</i> caused chlorosis on the top leaves but had no other effects on plant development. …”