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largest decrease » largest decreases (Expand Search), marked decrease (Expand Search)
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48621
Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma
Published 2025“…<b>A,</b> A cartoon demonstrating the experimental setup is shown. …”
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48622
List of identification results for the proteins that were differentially expressed between the normal NG108-15 cells and the senescent NG108-15 cells.
Published 2014“…a<p>. According to SWISS-PROT DE line.</p>b<p>. …”
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48623
MMV291 analogues interfere with actin polymerisation in the presence of profilin in vitro.
Published 2023“…Source data can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002066#pbio.3002066.s016" target="_blank">S1 Data</a>.…”
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48624
DN calpain-1 supports integration of vascular cord networks by enhancing the microtubule cytoskeleton.
Published 2010“…<p>(A) MVECs transduced with DN calpain-I or calpastatin peptide (200 nM) exhibited a robust microtubule cytoskeleton relative to Empty Vector controls. …”
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48625
NF-κB regulates <i>gTlr9</i> alternative splicing.
Published 2016“…In contrast, inhibition of AP-1 under stimulation selectively increased the expression of <i>9B</i> only, thus decreased <i>9A</i>/<i>9B</i> ratio (gray bars in each panel) (<b>2D-F</b>). …”
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48626
Analysis of TMD-effector translocation in mutants of the T4CC.
Published 2024“…</b> Relative translocation of indicated effectors in the wild type bacteria as well as in a DotM mutant (DotM1) with decreased ability to bind Glutamine-rich peptides [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012118#ppat.1012118.ref016" target="_blank">16</a>] and in strains lacking <i>icmS</i>, <i>icmW</i>, respectively. …”
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48627
The LPal inputs to RS neurons are relayed in the PT.
Published 2018“…Each black trace is a mean of 10 individual responses (colored traces). …”
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48628
DataSheet_1_Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing—Using Rifampicin as an Example.docx
Published 2020“…Moreover, the imprecision (relative root mean square error) and bias in predicted doses using MIPD with IOV decreased statistically significant when a second sampling occasion was added (difference in imprecision: −9.1%, bias: −7.7%), but only marginally including a third (difference in imprecision: −0.1%, bias: −0.1%). …”
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48629
Image 1_Population pharmacokinetics of polymyxin B in critically ill patients with carbapenem-resistant organisms infections: insights from steady-state trough and peak plasma conc...
Published 2025“…Bland-Altman analysis revealed a mean bias of 12.98 mg·h·L<sup>-1</sup> between the two AUC<sub>ss,24h</sub> estimation methods. …”
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48630
B Cell-Based Seamless Engineering of Antibody Fc Domains - Fig 7
Published 2016“…<p><b>Generation of Fc-mutated antibodies with enhanced affinity to Fc</b>γ<b>RIIIa</b> A) Design of donor vectors to generate hIgG1-Fc variants with mutated Fc, which were reported previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref036" target="_blank">36</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref038" target="_blank">38</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref044" target="_blank">44</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0167232#pone.0167232.ref046" target="_blank">46</a>]. …”
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48631
Effect of apicomplexan infections on the scallop condition.
Published 2015“…The whole and broken horizontal red lines represent the normal mean range of gonad weight observed by Thorarinsdottir [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0144685#pone.0144685.ref015" target="_blank">15</a>] from a healthy population of scallops in 1988–1990. …”
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48632
Table_1_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.docx
Published 2021“…SAT was monitored with a sensor on the neck of the subjects. On a separate day, a 12-lead-ECG-monitored maximum static apnea was repeated dry (n = 6).…”
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48633
Data_Sheet_2_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.zip
Published 2021“…SAT was monitored with a sensor on the neck of the subjects. On a separate day, a 12-lead-ECG-monitored maximum static apnea was repeated dry (n = 6).…”
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48634
Data_Sheet_1_Extreme Hypoxia Causing Brady-Arrythmias During Apnea in Elite Breath-Hold Divers.zip
Published 2021“…SAT was monitored with a sensor on the neck of the subjects. On a separate day, a 12-lead-ECG-monitored maximum static apnea was repeated dry (n = 6).…”
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48635
Effects of GCGR interactor overexpression on glucagon-induced cAMP accumulation in primary mouse hepatocytes, CHO cells expressing GCGR and HepG2 stably expressing GCGR.
Published 2015“…Overexpression of YWHAB in hepatocytes decreased glucagon induced cAMP accumulation (**p<0.01 when compared to hepatocytes transfected with pcDNA3.1).The results are shown as mean ± S.E. …”
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48636
Supplementary Material for: Comparison of Postoperative Neurocognitive Function in Older Adult Patients with and without Diabetes Mellitus
Published 2022“…Repeated measures ANOVA showed that mean DM patient TICS-M scores decreased 30 days postoperative (<i>F</i>(2, 200) = 4.0, <i>p</i> = 0.02), with subsequent recovery 6-month postoperative, compared to stable TICS-M scores in non-DM patients. …”
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48637
Loss of dendritic arbor complexity subsequent to ischemic stroke in ipsilateral layer II/III and layer V neurons of the motor cortex.
Published 2021“…Note that all parameters of dendritic complexity at the ipsilateral side decreased subsequent to MCAO and that layer II/III neurons responded faster, as they already show the decreased dendritic arborization at 6 hours after MCAO (for contralateral data, see <b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001399#pbio.3001399.s003" target="_blank">S3 Fig</a></b>). …”
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48638
PKM2 is efficiently deleted in mature mSC of mutant mice.
Published 2022“…<p><b>A</b>- Quantitative RT-PCR on sciatic nerve extracts shows decreased PKM1 and increased PKM2 expressions during mSC maturation. …”
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48639
Data_Sheet_2_Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study.pdf
Published 2020“…In patients who decreased and/or stopped ≥1 IST, mean daily doses of PRED, AZA, and MMF decreased between OLE baseline and last assessment by 60.8% [standard deviation (SD), 28.07; P < 0.0001], 89.1% (SD, 25.77; P < 0.0001), and 56.0% (SD, 32.99; P < 0.0001), respectively. …”
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48640
Data_Sheet_1_Concomitant Immunosuppressive Therapy Use in Eculizumab-Treated Adults With Generalized Myasthenia Gravis During the REGAIN Open-Label Extension Study.pdf
Published 2020“…In patients who decreased and/or stopped ≥1 IST, mean daily doses of PRED, AZA, and MMF decreased between OLE baseline and last assessment by 60.8% [standard deviation (SD), 28.07; P < 0.0001], 89.1% (SD, 25.77; P < 0.0001), and 56.0% (SD, 32.99; P < 0.0001), respectively. …”