Cardioprotection in <i>Akr1b3</i> null I/R mice. by Devi Thiagarajan (4633981)

“…<p>Male WT and <i>Akr1b3</i> null mice were subjected to LAD occlusion followed by reperfusion at age 4 months. (A) Western blot analysis of AKR1B3 in heart tissue lysate at 48 h post-LAD was performed and normalized to levels of B-ACTIN, N = 4 mice/genotype. …”

Table_2_Effects of Aerobic Exercise Training on Systemic Biomarkers and Cognition in Late Middle-Aged Adults at Risk for Alzheimer’s Disease.xlsx by Julian M. Gaitán (9455079)

“…To begin to address this issue, we utilized blood samples of 23 asymptomatic late middle-aged adults, with familial and genetic risk for AD (mean age 65 years old, 50% female) who underwent 26 weeks of supervised treadmill training. …”

Isolated coronary arteriole vasoreactivity. by Natia Q. Kelm (5683982)

“…<p>Endothelin-induced vasoconstriction in coronary arterioles was similar between all groups (A). Coronary arterioles from O+EC or O+SVF decreased sensitivity to the low doses of bradykinin (O+EC group in 1e^-13 and 1e^-12 concentrations and O+SVF in 1e^-12 and 1e^-11 concentrations). …”

Effect of fisetin on cisplatin-induced renal inflammation. by Bidya Dhar Sahu (625284)

“…<p>(<b>A</b>) Effect of fisetin on cisplatin-induced changes in protein expression of inducible nitric oxide (iNOS) in kidney tissues of control and treated groups. …”

Minor effects in neurological deficits and body weight gain presented by CMVMJD135 mice upon VPA treatment. by Sofia Esteves (818640)

“…<p>(A) Decreased body weight gain in CMVMJD135 VPA-treated animals compared to CMVMJD135 vehicle-treated animals; (B) no improvement of VPA-treated animals in grip strength as assessed through the hanging wire test; (C) Improvement in spontaneous locomotor activity at 24 weeks of age; (D,E,F) No improvement in spontaneous activity (vertical movement), in tremors and limb clasping, respectively, (G) transient improvement in footdragging severity at 14 weeks, and (H) tendency toward an improvement in stride length at 22 and 24 weeks of age. …”

GK rat glucose, body weight, and food intake are affected by 28 days treatment with AgoPAMs or partial agonist. by Michele J. Pachanski (4042670)

“…Data are mean ± SEM with analysis via ANOVA followed by Tukey’s posttest. * <i>P < 0</i>.…”

DataSheet2_Anthropogenic heat due to energy consumption contributes to cooler and wetter summers in Southwest China.pdf by Mengyi Zhang (7454231)

“…<p>Anthropogenic heat release is the release of heat generated by anthropogenic energy consumption. The regional mean Anthropogenic heat release flux in Southwest China grew quickly from 0.06 Wm^-2 in 1992 to a peak of 0.37 Wm^-2 in 2019. …”

Snail1 loss altered cytoskeletal organization and gene expressions in RMG1 cells. by Misako Haraguchi (768459)

“…Snail1 KO1 cells showed a complete loss of Snail1 expression and an increase in E-cadherin, occludin and claudin-1, beta-actin, alpha- tubulin, as well as a decreased in integrin alpha 5 expression. …”

Titan cells generation <i>in vitro</i> is impacted by various environmental conditions. by Benjamin Hommel (523072)

“…<p>(<b>A</b>) The sequence of media used at steps 2 and 3 of the protocol was crucial for titan cells generation: yeasts cultured in Yeast Peptone Dextrose (YPD) and transferred to minimal medium (MM) produced significantly more titan cells (cells >10μm, dotted grey line) than yeasts cultured in MM or YPD and transferred in MM or YPD, respectively; (<b>B</b>) Exposure to d light at step 3 had a positive impact on titan cells generation compared to incubation in the dark; (<b>C</b>) Raising the incubation temperature to 37°C at step 3 decreased titan cells formation compared to 30°C; (<b>D</b>) Modification of the initial pH of the MM used at step 3 impacted titan cells formation with pH 5.5 being optimal while a more acidic (pH = 4), a neutral (pH = 7) or an alkaline (pH = 8.5) pH inhibited titan cells formation; (<b>E</b>) The impact of hypoxia was tested by physical (closed cap) and by chemical (COCl₂ in MM at 1 nM) method and compared to normoxia (21% oxygen). …”

Effects of AKT1 <i>rs1130233</i> on AKT1 protein expression and NRG1-stimulated Ser-473 phosphorylation of AKT1in B lymphoblasts derived from controls and patients with schizophren... by Yoshitatsu Sei (83124)

“…The minor <i>rs1130233</i> allele was associated with lower expression of AKT1 protein (AKT1/β-actin ratio, mean±SE). p = 0.006, <i>rs1130233</i> G/A vs. G/G; p = 0.0406. …”

Presentation_1_CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression.pptx by Alexander T. H. Cocker (8436300)

“…We found in 757 individuals, from a combined 28 studies and 6 datasets, that the CD56neg subset constitutes 5.67% of NK cells in healthy peripheral blood, while HIV-1 infection increases this population by a mean difference of 10.69%. …”

Data_Sheet_1_Managing African Swine Fever: Assessing the Potential of Camera Traps in Monitoring Wild Boar Occupancy Trends in Infected and Non-infected Zones, Using Spatio-Tempora... by Martijn Bollen (11550388)

“…Our results show that (1) occupancy rates at the onset of our monitoring period reflect the ASF infection status; (2) ASF-induced mortality and culling efforts jointly lead to decreased occupancy over time; and (3) the estimated mean total extinction rate ranges between 22.44 and 91.35%, depending on the ASF infection status. …”

DataSheet_1_CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression.pdf by Alexander T. H. Cocker (8436300)

“…We found in 757 individuals, from a combined 28 studies and 6 datasets, that the CD56neg subset constitutes 5.67% of NK cells in healthy peripheral blood, while HIV-1 infection increases this population by a mean difference of 10.69%. …”

Table1_The ventilatory response to hypoxia is blunted in some preterm infants during the second year of life.docx by Zoe Freislich (14010888)

“…</p>Results<p>Thirty nine infants born very preterm demonstrated a mean (SD) HVR of 11.4 (10.1)% (increase in V_E) in response to decreasing F_IO₂ from 0.21 to 0.14. …”

Identification of vigilance states in the neonatal mouse. by Nicholas Rensing (3686332)

“…<p>(<b>A</b>) Representative 15 second EEG and nuchal EMG traces from a postnatal day 9 (P9) mouse exhibit a discontinuous EEG pattern during periods of high muscle tone (upper traces) and muscle atonia (lower traces). …”

Table_1_Discordance Between Stimulated and Spontaneous Growth Hormone Levels in Short Children Is Dependent on Cut-Off Level and Partly Explained by Refractoriness.docx by Otto Lennartsson (9649142)

“…Divergent results were defined as having a pathological response on only one of the tests when using 3, 5, 7, and 10 µg/L as cut-offs for peak GH on both tests, 1.1 and 3.3 µg/L for mean nocturnal values and receiver operating characteristic curves-derived cut-offs for nocturnal values.…”

Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx by José Fidel Baizabal-Carvallo (11416508)

“…Among patients with non-motor symptoms in the top three tiers, those with a PIGD phenotype or prominent dyskinesia exhibited a higher frequency of fatigue, insomnia, pain, and anxiety, suggesting a clustering effect of non-motor symptoms with these motor presentations.…”

Functional pathways for which cell-to-cell heterogeneity in expression correlates with proliferation rate across cell types and species. by Zhisheng Jiang (10486235)

“…<b>(E)</b> Pearson correlations of mean expression (average of log2(TPM+1)) of ribosome biogenesis genes vs proteasome genes across organ developmental time courses in seven species (see also <b><a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009582#pcbi.1009582.s002" target="_blank">S2 Fig</a></b>).…”

Datasheet1_Oscillometric measurement of the ankle-brachial index and the estimated carotid-femoral pulse wave velocity improves the sensitivity of an automated device in screening... by Krisztina Fendrik (17618109)

“…</p>Methods<p>Among 230 patients (mean age 64 ± 14 years), ABI measurements were performed using a Doppler device and a manual sphygmomanometer. …”

Image_1_Deep brain stimulation in Early Onset Parkinson's disease.JPEG by Patricia Krause (9398407)

“…These improvements were accompanied by a significant 59% LEDD reduction (p < 0.001), a significant 6.6 ± 16.1 points reduction of impulsivity (p = 0.02; n = 35) and a significant 30 ± 50% improvement of QoL (p = 0.01). …”