Image_1_Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats.TIF by Xiangnan Du (8552319)

“…ACF also reversed the activation of the Akt signaling pathway induced by RIPC following stroke. HIF may play a key role in RIPC, which was likely mediated by the Akt signaling pathway and systemic modulation of the inflammatory response in aged rats.…”

Thymosin Beta 4 Protects Cardiomyocytes from Oxidative Stress by Targeting Anti-Oxidative Enzymes and Anti-Apoptotic Genes by Chuanyu Wei (145756)

“…<div><h3>Background</h3><p>Thymosin beta-4 (Tβ4) is a ubiquitous protein with many properties relating to cell proliferation and differentiation that promotes wound healing and modulates inflammatory mediators. …”

The GOAT-Ghrelin System Is Not Essential for Hypoglycemia Prevention during Prolonged Calorie Restriction by Chun-Xia Yi (182031)

“…<div><h3>Objective</h3><p>Ghrelin acylation by ghrelin O-acyltransferase (GOAT) has recently been reported to be essential for the prevention of hypoglycemia during prolonged negative energy balance. Using a unique set of four different genetic loss-of-function models for the GOAT/ghrelin/growth hormone secretagogue receptor (GHSR) system, we thoroughly tested the hypothesis that lack-of-ghrelin activation or signaling would lead to hypoglycemia during caloric deprivation.…”

Image_2_Peri-interventional Triple Therapy With Dabigatran Improves Vasomotion and Promotes Endothelialization in Porcine Coronary Stenting Model.TIF by Rayyan Hemetsberger (5056196)

“…<p>Objective: We evaluated the short and long-term effect of peri-interventional dabigatran therapy on vasomotion, endothelialization, and neointimal formation in a porcine coronary artery stenting model.</p><p>Background: Stenting of coronary arteries induces local inflammation, impairs vasomotion and delays endothelialization.…”

Targeted Deletion of <em>Nrf2</em> Reduces Urethane-Induced Lung Tumor Development in Mice by Alison K. Bauer (200457)

“…<div><p>Nrf2 is a key transcription factor that regulates cellular redox and defense responses. …”

Image_1_Residual OXPHOS is required to drive primary and metastatic lung tumours in an orthotopic breast cancer model.tif by Patries Herst (18472197)

“…Background<p>Fast adaptation of glycolytic and mitochondrial energy pathways to changes in the tumour microenvironment is a hallmark of cancer. Purely glycolytic ρ⁰ tumour cells do not form primary tumours unless they acquire healthy mitochondria from their micro-environment. …”

Table_3_Genome-Wide Analysis of NF-Y Genes in Potato and Functional Identification of StNF-YC9 in Drought Tolerance.docx by Shigui Li (143517)

“…However, little is known about this family in potato. In the present study, a total of 41 StNF-Y genes were identified in the potato genome. …”

Table_1_Dietary omega-3 polyunsaturated fatty acids reduce cytochrome c oxidase in brain white matter and sensorimotor regions while increasing functional interactions between neur... by Carley Rivers (19986186)

Change of cell phenotype in the lungs of mice after resuscitated hemorrhagic shock and tissue trauma (HS/T) and the cell resource of type 2 cytokine interleukin (IL) 5. by Jing Xu (1234089)

“…<p>A: IL5⁺ gate from lung CD45⁺ cells was increased in the lung after HS/T, peaked at 6 hours after HS/T (<i>n</i> = 5–9/group). …”

Image_8_Insights Into the MYB-Related Transcription Factors Involved in Regulating Floral Aroma Synthesis in Sweet Osmanthus.JPEG by Xin Yan (17064)

“…In this study, we conducted a genome-wide analysis of MYB-related proteins in sweet osmanthus; 212 OfMYB-related TFs were divided into three distinct subgroups based on the phylogenetic analysis. …”

DataSheet4_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”

DNA Hypermethylation of <i>CREB3L1</i> and <i>Bcl-2</i> Associated with the Mitochondrial-Mediated Apoptosis via PI3K/Akt Pathway in Human BEAS-2B Cells Exposure to Silica Nanopart... by Yang Zou (102732)

“…In this study, the epigenetic regulation of low-dose exposure to SiNPs was evaluated in human bronchial epithelial BEAS-2B cells over 30 passages. Cell viability was decreased in a dose- and passage-dependent manner. …”

Baseline analysis, continuous factors. by Hiroaki Yoshikawa (4615801)

“…</p><p>Results</p><p>Our analysis revealed a significantly older age of onset in the 2018 cohort compared to 2006. …”

DataSheet1_Effect of salt stress on the biomass productivity and potential bioenergy feedstock of Graesiella emersonii KNUA204 isolated from Ulleungdo Island, South Korea.docx by Jeong-Mi Do (14306189)

“…Therefore, the treatment of G. emersonii KNUA204 with MgCl₂ during cultivation could provide a microalgae-based bioenergy feedstock with high productivity.…”

Table_3_Microbial community diversity of an integrated constructed wetland used for treatment of sewage.XLSX by Nidhi Seth (18173680)

“…<p>The microbial community diversity in Constructed Wetland System (CWS) plays a key role in the removal of pollutants from waste water. …”

Exercise Training Attenuates Sympathetic Activity and Improves Morphometry of Splenic Arterioles in Spontaneously Hipertensive Rats by Marina de Paiva Lemos (4704679)

“…SHRS (182.5 ± 4.2 mmHg, p < 0.001). The WKYT showed a higher vagal effect (∆HR: 79.0 ± 2.3 bpm) compared with WKYS (∆HR: 67.4 ± 1.7 bpm; p < 0.05). …”

Image_1_10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.TIF by Pei Fan (404125)

“…To the best of our knowledge, our results provide the first concrete evidence that 10-HDA-scavenged •OH could be a potential pharmacological application for maintaining vascular health.…”

Aboveground residue C and N inputs under elevated CO₂ and O₃. by Lei Cheng (171055)

“…Data represent means (n = 4) ± s.e.m. (a) Residue C inputs. Soybean residue C inputs: CO₂ effect, <i>P</i>≤0.001 for every year; O₃ effect, <i>P</i><0.05 for every year; CO₂×O₃, <i>P</i>>0.1 for every year. …”

Image_2_Changes in Thoracic Cavity Volume After Bilateral Lung Transplantation.TIF by Woo Sik Yu (6551513)

“…</p>Methods<p>We reviewed 89 patients who underwent a pre-LTx pulmonary function test (PFT), chest computed tomography (CT) scan, and 1-year follow-up CT after LTx. …”

<i>FTO</i> Obesity Risk Variants Are Linked to Adipocyte <i>IRX3</i> Expression and BMI of Children - Relevance of <i>FTO</i> Variants to Defend Body Weight in Lean Children? by Kathrin Landgraf (350164)

“…</p><p>Conclusion</p><p>One interpretation of our observation of <i>FTO</i> risk variants linked to <i>IRX3</i> expression and adipocyte size restricted to lean children, along with the decreased <i>IRX3</i> expression in obese compared to lean peers, may reflect a defense mechanism for protecting body-weight, which is pertinent for lean children.…”