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225321
Myeloid cell comparison.
Published 2024“…This infection can lead to neurological effects and establish a viral reservoir. Given the gaps in our understanding of how these cells respond <i>in vivo</i> to acute CNS infection, we conducted single-cell RNA sequencing (scRNA-seq) on myeloid cells from the brains of three rhesus macaques 12 days after SIV infection, along with three uninfected controls. …”
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225322
Table_1_High-Throughput Analysis of Water-Soluble Forms of Choline and Related Metabolites in Human Milk by UPLC-MS/MS and Its Application.DOCX
Published 2021“…In order to enable the rapid assessment of choline intake for exclusively breastfed infants and to further investigate the associations between milk choline and maternal and infant status and other outcomes, we have developed a simplified method for the simultaneous analysis of human milk choline, glycerophosphocholine, phosphocholine, and the less abundant related metabolites betaine, carnitine, creatinine, dimethylglycine (DMG), methionine, and trimethylamine N-oxide (TMAO) using ultraperformance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS). …”
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225323
Data Sheet 1_Relay intercropped soybean promotes nodules development and nitrogen fixation by root exudates deposition.docx
Published 2024“…This study was conducted to investigate the relationship between crop root exudates and soybean nodule development under intercropping patterns.</p>Method<p>A two years field experiments was carried out and combined with pot experiments to quantify the effects of planting mode, i.e., relay intercropping and monocropping, and genotypes, i.e., supernodulating NTS1007(NTS), Nandou-12(ND) and Guixia-3(GX) on root exudates, rhizobium community structure, nodule development and nitrogen fixation ability.…”
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225324
Enhanced immunity against SARS-CoV-2 in returning Chinese individuals
Published 2024“…Blood and throat swab specimens were collected from participants, and their immunity status was determined through competitive ELISA, microneutralization assay and enzyme-linked FluoroSpot assay. A total of 272 subjects were involved in the questionnaire survey, of whom 235 (86.4%) were returning Chinese individuals and 37 (13.6%) were foreigners. …”
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225325
Table_1_Chromatin Remodeling Protein ZmCHB101 Regulates Nitrate-Responsive Gene Expression in Maize.xlsx
Published 2020“…Here, we demonstrate that ZmCHB101 plays a pivotal regulatory role in nitrate-responsive gene expression. …”
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225326
DataSheet_1_Coexpression of HHLA2 and PD-L1 on Tumor Cells Independently Predicts the Survival of Spinal Chordoma Patients.docx
Published 2022“…</p>Conclusion<p>These data provide a better understanding of the immunosuppressive mechanism in chordoma and may be useful for the development of combination or novel immunotherapy approaches aiming to improve therapeutic efficacy and survival.…”
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225327
Data_Sheet_1_Antioxidant Activity and the Potential Mechanism of the Fruit From Ailanthus altissima Swingle.CSV
Published 2021“…<p>The fruits of Ailanthus altissima Swingle (AS) possess a variety of pharmacological activities. Its antioxidant activity and the potential mode of action have not yet been investigated. …”
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225328
Image_1_Intermittent Fasting Reshapes the Gut Microbiota and Metabolome and Reduces Weight Gain More Effectively Than Melatonin in Mice.tif
Published 2021“…</p><p>Objective: This study aimed to investigate the effects of IF on body fat and the gut microbiota and metabolome as well as a potential interaction with melatonin.</p><p>Methods: Male C57BL/6J mice (23.0 ± 0.9 g, 6 wk old) were randomly assigned into four groups (12 mice/group): control (C), intermittent fasting (F), melatonin (M), and intermittent fasting plus melatonin (MF). …”
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225329
Disease-associated mutations in human <i>TUBB3</i> disturb netrin repulsive signaling
Published 2019“…<div><p>Missense mutations in the human <i>TUBB3</i> gene cause a variety of neurological disorders associated with defects in axon guidance and neuronal migration, but the underlying molecular mechanisms are not well understood. …”
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225330
DataSheet_1_Analysis of Adaptive Olaparib Resistance Effects on Cisplatin Sensitivity in Triple Negative Breast Cancer Cells.docx
Published 2021“…OlaR TNBC cells express decreased levels of PARP-1 and Pol η, a translesion-synthesis polymerase important in platinum-induced interstrand crosslink repair. …”
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225331
Image_2_Deletion of Non-histidine Domains of Histidine Kinase CHK1 Diminishes the Infectivity of Candida albicans in an Oral Mucosal Model.TIF
Published 2022“…</p>Methods<p>The domain mutants CHK25 (<sup>ΔS_Tkc</sup>CHK1/Δchk1) and CHK26 (<sup>ΔS_TkcΔgaf</sup>CHK1/Δchk1) were first constructed by the his1-URA3-his1 method and confirmed by sequencing and Southern blots. A mouse tongue infection model was used to evaluate the hyphal invasion and fungal loads in each domain mutant, full-gene deletion mutant CHK21 (chk1Δ/chk1Δ), re-constituted strain CHK23 (chk1Δ/CHK1), and wild type (WT) from day 1 to day 5. …”
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225332
Data_Sheet_2_Comparison of Calcium Balancing Strategies During Hypothermic Acclimation of Tilapia (Oreochromis mossambicus) and Goldfish (Carassius auratus).PDF
Published 2018“…This difference can be attributed to alterations in the transportation parameters for Ca<sup>2+</sup> influx, i.e., maximum velocity (V<sub>max</sub>) and binding affinity (1/K<sub>m</sub>). There was also a significant difference in the regulation of Ca<sup>2+</sup> efflux between the two fishes. …”
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225333
Table 1_Epidemiological characteristics and trends of pre-hospital emergency care in Handan, China from 2011 to 2024.docx
Published 2025“…The Mann-Kendall (MK) trend test was employed to assess the trends of pre-hospital EMS demand, age distribution and disease occurrence patterns.</p>Results<p>A total of 613,066 pre-hospital EMS cases from 2011 to 2024 met inclusion criteria. …”
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225334
Table_1_Properdin inhibition ameliorates hepatic ischemia/reperfusion injury without interfering with liver regeneration in mice.docx
Published 2023“…Western blot showed decreased phosphorylation of only Erk1/2 among MAPKs (P =0.004). …”
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225335
DataSheet1_Mechanically durable tri-composite polyamide 6/hematite nanoparticle/tetra-n-butylammonium bromide (PA6/α-Fe2O3/TBAB) nanofiber based membranes for phosphate remediation...
Published 2024“…<p>Essential properties for a Point of Use (POU) water filter include maintaining high removal capacity and rate, with excellent mechanical properties to withstand pressure drop. …”
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225336
Image_1_Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer’s Disease in 5XFAD Mouse Model.tif
Published 2020“…</p>Methods<p>Proteomic, bioinformatics analysis, multiple reaction monitoring (MRM), western blotting (WB) or ELISA were performed for analyzing these urinary exosomes.</p>Results<p>A total of 316 proteins including 44 brain cell markers were identified using liquid chromatography tandem mass spectrometry. …”
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225337
Table_2_Impact of inhibition of the renin-angiotensin system on early cardiac and renal abnormalities in Sprague Dawley rats fed short-term high fructose plus high salt diet.DOCX
Published 2024“…Introduction<p>The combination of a high fructose and high salt diet typical of western diet induces high blood pressure, aortic stiffening, left ventricular (LV) diastolic dysfunction and impaired renal function in rodents. …”
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225338
Effect of SILD on cardiac hypertrophy and macrophage infiltration.
Published 2015“…<p>(A) Representative photomicrographs of H&E-stained heart from CTRL, SILD, STZ and STZ+SILD mice on harvesting (bar represents 100μm).…”
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225339
Image_1_JAK2V617F Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.tif
Published 2021“…<p>A substitution mutation of valine to phenylalanine at codon encoding position 617 of the Janus kinase 2 (JAK2) gene (JAK2<sup>V617F</sup>) has been detected in myeloid cells of some individuals with higher levels of proinflammatory cytokine production such as interleukin (IL)-6. …”
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225340
Table_1_Screening for potential warning biomarkers in cows with ketosis based on host–microbiota co-metabolism analysis.DOCX
Published 2024“…Lithocholic acid in the plasma was a potential ketosis warning metabolite 7 days before delivery.…”