<i>microRNA-135a-5p</i> regulates <i>NOD-like receptor family pyrin domain containing 3</i> inflammasome-mediated hypertensive cardiac inflammation and fibrosis <i>via thioredoxin-... by Hao Chen (5190)

“…Moreover, over-expression of <i>miR-135a-5p</i> resulted in inhibition of inflammatory infiltration and almost eliminated cardiac fibrosis, as evidenced by decreased Collagen (COL)-I, COL-III, a-smooth muscle actin, <i>NLRP3</i>, tumor necrosis factor-α, and interleukin-6. …”

MiR-200a and miR-200b restrain inflammation by targeting ORMDL3 to regulate the ERK/MMP-9 pathway in asthma by Xiao-Jun Duan (9279077)

“…Therefore, elevating miR-200a and miR-200b and decreasing ORMDL3 might be potential strategies for inhibition of the asthma process.…”

Table_1_Identification and characterization of CLEC11A and its derived immune signature in gastric cancer.xlsx by Qing Zheng (659747)

“…Moreover, the flow cytometry assay showed that the knock-down of CLEC11A increased the infiltration of cytotoxic CD8+ T cells and helper CD4+ T into tumors while decreasing the percentage of M2 macrophages, MDSCs, and Tregs.…”

DataSheet_1_Hypercholesterolemia Correlates With Glomerular Phospholipase A2 Receptor Deposit and Serum Anti-Phospholipase A2 Receptor Antibody and Predicts Proteinuria Outcome in... by Lei Dong (165252)

“…Background<p>The anti-phospholipase A2 receptor (PLA2R) antibody is a non-invasive diagnostic tool and prognosis predictor of idiopathic membranous nephropathy (IMN). …”

Data_Sheet_1_miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.PDF by Na Li (6550)

“…Furthermore, EMT was induced, as shown by increased N-cadherin, vimentin, MMP2, and MMP9 and decreased E-cadherin in the placenta accreta spectrum group and in HTR-8/SVneo cells transfected with miR-193a-3p mimics or si-EFNB2. …”

Image_1_miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.TIFF by Na Li (6550)

“…Furthermore, EMT was induced, as shown by increased N-cadherin, vimentin, MMP2, and MMP9 and decreased E-cadherin in the placenta accreta spectrum group and in HTR-8/SVneo cells transfected with miR-193a-3p mimics or si-EFNB2. …”

Data_Sheet_1_Small Molecule Inhibitor Adjuvant Surfactant Therapy Attenuates Ventilator- and Hyperoxia-Induced Lung Injury in Preterm Rabbits.pdf by Pragnya Das (8692077)

“…Background<p>Invasive mechanical ventilation (IMV) has become one of the mainstays of therapy in NICUs worldwide, as a result of which premature babies with extremely low birth weight have been able to survive. …”

X-ray Single-Crystal Structure and Magnetic Properties of Fe[CH₃PO₃)]·H₂O:  A Layered Weak Ferromagnet by Carlo Bellitto (2069203)

“…Below 100 K, the magnetic moment of Fe[CH₃PO₃]·H₂O rises rapidly to a maximum at <i>T</i>_max ≅ 24 K, and then it decreases again. …”

Image_2_Small Molecule Inhibitor Adjuvant Surfactant Therapy Attenuates Ventilator- and Hyperoxia-Induced Lung Injury in Preterm Rabbits.TIF by Pragnya Das (8692077)

“…Background<p>Invasive mechanical ventilation (IMV) has become one of the mainstays of therapy in NICUs worldwide, as a result of which premature babies with extremely low birth weight have been able to survive. …”

DataSheet1_Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain.docx by Malene Brohus (840080)

“…The disease mechanisms have been attributed to dysregulation of RyR2, for Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) and/or Ca_V1.2, for Long-QT Syndrome (LQTS). Recently, a novel CALM2 variant, G114R, was identified in a mother and two of her four children, all of whom died suddenly while asleep at a young age. …”

Image_1_Small Molecule Inhibitor Adjuvant Surfactant Therapy Attenuates Ventilator- and Hyperoxia-Induced Lung Injury in Preterm Rabbits.TIF by Pragnya Das (8692077)

“…Background<p>Invasive mechanical ventilation (IMV) has become one of the mainstays of therapy in NICUs worldwide, as a result of which premature babies with extremely low birth weight have been able to survive. …”

Expression of CHDH protein is decreased in sperm and primary hepatocytes from humans who are heterozygous or homozygous for the rs12676 SNP. by Amy R. Johnson (168149)

Inhibition of PKA by siRNA increased cell proliferation and decreases apoptosis in endothelial cells under high glucose treatment. by Zhaoyun Zhang (118032)

“…<p>Cells were transfected with siRNA and then treated with 5.6 mM glucose or 25 mM glucose for 72 hours: A: siRNA enhanced cell proliferation under high glucose conditions B: siRNA decreased apoptosis under high glucose conditions. *, p<0.05 compared with 5.6 mM condition. n = 6.…”

Knockdown of <i>Nf1</i> in <i>Rdl</i>-expressing neurons decreases sleep and increases metabolic rate. by Elizabeth B. Brown (4582978)

DataSheet_1_Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages.docx by Qianqian Li (386223)

“…Mechanistically, RNA-sequencing analysis showed that Nr4a1, a nuclear receptor known to have potent anti-inflammatory effects, is involved in Lcn10-mediated macrophage activation. …”

DataSheet_2_Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages.xlsx by Qianqian Li (386223)

“…Mechanistically, RNA-sequencing analysis showed that Nr4a1, a nuclear receptor known to have potent anti-inflammatory effects, is involved in Lcn10-mediated macrophage activation. …”

Cortical distribution of neurons born at E11.5, E13.5, E15.5, or E17.5 in P0 mice. by Qingfa Chen (739620)

“…Both the mutant and the control embryos show a similar cortical layer structure. However, the total number of CUX1+ cells at P0 decreased in <i>Nestin;Epha4</i>^<i>fx/fx</i> (A) but increased in <i>GFAP;Epha4</i>^<i>fx/fx</i> (B) mice compared to controls. …”

Table_2_Decreased levels of discomfort in repeatedly handled mice during experimental procedures, assessed by facial expressions.PDF by Julia Swan (14556800)

Table_1_Serum Metrnl levels are decreased in subjects with overweight or obesity and are independently associated with adverse lipid profile.docx by Xiaoyu Ding (391861)

Image 2_Sediment exposure decreases diversity in the surface mucus layer microbiome of Porites lobata at Honoliʻi, Hawaiʻi.jpeg by Joseph W. P. Nakoa (21796214)