Discovery of Novel Glucose-Regulated Proteins in Isolated Human Pancreatic Islets Using LC–MS/MS-Based Proteomics by Alexandra C. Schrimpe-Rutledge (2067694)

“…The prevalence of diabetes mellitus is increasing dramatically throughout the world, and the disease has become a major public health issue. The most common form of the disease, type 2 diabetes, is characterized by insulin resistance and insufficient insulin production from the pancreatic beta-cell. …”

Discovery of Novel Glucose-Regulated Proteins in Isolated Human Pancreatic Islets Using LC–MS/MS-Based Proteomics by Alexandra C. Schrimpe-Rutledge (2067694)

“…The prevalence of diabetes mellitus is increasing dramatically throughout the world, and the disease has become a major public health issue. The most common form of the disease, type 2 diabetes, is characterized by insulin resistance and insufficient insulin production from the pancreatic beta-cell. …”

Tongxinluo attenuates reperfusion injury in diabetic hearts by angiopoietin-like 4-mediated protection of endothelial barrier integrity via PPAR-α pathway by Kang Qi (703361)

“…In I/R-injured diabetic hearts, TXL treatment remarkably reduced the infarct size, and protected endothelial barrier integrity demonstrated by decreased endothelial cells apoptosis, microvascular permeability, and myocardial hemorrhage, fortified tight junction, and upregulated expression of JAM-A, integrin-α5, and VE-cadherin, and these effects of TXL were as effective as insulin and rhAngptl4. …”

Table_1_Exosomal Circular RNA RNA-seq Profiling and the Carcinogenic Role of Exosomal circ-CYP24A1 in Cutaneous Squamous Cell Carcinoma.XLSX by Zheng Zhang (88857)

“…Meanwhile, si-circ-CYP24A1-transfected exosomes significantly decreased the expression of downstream targets CDS2, MAVS, and SOGA in cSCC cells.…”

Discovery of Novel Glucose-Regulated Proteins in Isolated Human Pancreatic Islets Using LC–MS/MS-Based Proteomics by Alexandra C. Schrimpe-Rutledge (2067694)

“…The prevalence of diabetes mellitus is increasing dramatically throughout the world, and the disease has become a major public health issue. The most common form of the disease, type 2 diabetes, is characterized by insulin resistance and insufficient insulin production from the pancreatic beta-cell. …”

Discovery of Novel Glucose-Regulated Proteins in Isolated Human Pancreatic Islets Using LC–MS/MS-Based Proteomics by Alexandra C. Schrimpe-Rutledge (2067694)

“…The prevalence of diabetes mellitus is increasing dramatically throughout the world, and the disease has become a major public health issue. The most common form of the disease, type 2 diabetes, is characterized by insulin resistance and insufficient insulin production from the pancreatic beta-cell. …”

Data_Sheet_1_Recombinant Factor VIII Fc Inhibits B Cell Activation via Engagement of the FcγRIIB Receptor.PDF by Maria T. Georgescu (8422683)

“…B cells from FVIII-exposed hemophilia A mice also exhibited decreased extracellular signal-regulated kinase (ERK) phosphorylation when exposed to rFVIIIFc. …”

miR-17-5p overexpression and subsequent paclitaxel treatment induced mitochondrial pathway mediated apoptosis in A549-T24 cells. by Abhisek Chatterjee (584727)

“…<p>(A–B) Overexpression of miR-17-5p induced apoptosis in paclitaxel resistant lung cancer cells. …”

Table_1_The Extent of Human Apolipoprotein A-I Lipidation Strongly Affects the β-Amyloid Efflux Across the Blood-Brain Barrier in vitro.docx by Roberta Dal Magro (5474120)

“…Finally, when apoA-I folded its structure in discoidal HDL, rather than in spherical ones, it was able to cross the BBB in vitro and strongly destabilize the conformation of Aβ fibrils by decreasing the order of the fibril structure (-24%) and the β-sheet content (-14%). …”

Simultaneous loss of <i>prrx1a/b</i> and <i>jag1b</i> further improves ventral cartilages in <i>edn1</i> mutants. by Lindsey Barske (3174918)

“…(F) Quantification of skeletal rescue in <i>prrx1a</i>; <i>prrx1b</i>; <i>edn1</i> mutants (left column) and <i>jag1b</i>; <i>edn1</i> mutants with decreasing numbers of wild-type <i>prrx1a/b</i> alleles (e.g. 4 wild-type alleles = pure <i>jag1b</i>; <i>edn1</i> mutants; 0 wild-type alleles = quadruple mutant). …”

DataSheet_1_Threonyl-tRNA Synthetase Promotes T Helper Type 1 Cell Responses by Inducing Dendritic Cell Maturation and IL-12 Production via an NF-κB Pathway.pdf by Hak-Jun Jung (7369292)

“…Importantly, TRS-stimulated DCs significantly increased the populations of IFN-γ⁺CD4 T cells, and the levels of IFN-γ when co-cultured with CD4⁺ T cells. The addition of a neutralizing anti-IL-12 mAb to the cell cultures of TRS-treated DCs and CD4⁺ T cells resulted in decreased IFN-γ production, indicating that TRS-stimulated DCs may enhance the Th1 response through DC-derived IL-12. …”

Data_Sheet_1_WAY-100635 Alleviates Corneal Lesions Through 5-HT1A Receptor-ROS-Autophagy Axis in Dry Eye.docx by Xujiao Zhou (6661499)

“…</p><p>Results: 5-HT_1A receptor agonist (8-OH-DPAT) increased corneal fluorescein sodium staining spots and 5-HT_1A receptor antagonist (WAY-100635) decreased them. …”

Zoster vaccination inequalities: A population based cohort study using linked data from the UK Clinical Practice Research Datalink by Anu Jain (4634890)

“…Uptake decreased with increasing levels of deprivation (p-value for trend<0.0001; aOR most deprived versus least deprived areas = 0.69 (95%CI: 0.64–0.75)). …”

Kaplan-Meier graph illustrating cardiovascular mortality in participants with NYHA functional class III during a follow-up period of 12 years of those supplemented with selenium an... by Urban Alehagen (796660)

Data_Sheet_1_Frequency-Dependent Competition Between Strains Imparts Persistence to Perturbations in a Model of Plasmodium falciparum Malaria Transmission.pdf by Qixin He (491080)

“…It underlies a series of fundamental epidemiological characteristics, including large reservoirs of transmission from high prevalence of asymptomatics and long-lasting infections. …”

Data_Sheet_1_Frequency-Dependent Competition Between Strains Imparts Persistence to Perturbations in a Model of Plasmodium falciparum Malaria Transmission.pdf by Qixin He (491080)

“…It underlies a series of fundamental epidemiological characteristics, including large reservoirs of transmission from high prevalence of asymptomatics and long-lasting infections. …”

Expression of structural proteins and calcium pump in the heart after trauma. by Miriam Kalbitz (3150195)

“…<p>Altered expression of z-disc proteins and calcium pump SERCA after blunt chest trauma in the heart. A. Decrease in desmin expression 24 h and 5 d after blunt chest trauma compared to sham procedure. …”

Table_1_Soil Aggregation Shaped the Distribution and Interaction of Bacterial-Fungal Community Based on a 38-Year Fertilization Experiment in China.docx by Jie Chen (5892)

Presentation_1_Soil Aggregation Shaped the Distribution and Interaction of Bacterial-Fungal Community Based on a 38-Year Fertilization Experiment in China.zip by Jie Chen (5892)

Fold change in humoral and cellular response magnitudes from RV305 week 2 to week 26. by LaTonya D. Williams (3140490)