Dysregulation of systemic and mucosal humoral responses to microbial antigens in HIV-1-infected individuals. by Zdenek Hel (337869)

“…Epithelial cell apoptosis and decreased availability of antigen-specific IgG and IgA in mucosal secretions result in enhanced translocation of microbial products and whole bacteria across the intestinal mucosal barrier into the systemic circulation.…”

Data_Sheet_1_In vitro study of ATP1A3 p.Ala275Pro mutant causing alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism.pdf by Dan-dan Ruan (12508987)

“…</p>Conclusion<p>This study reveals that the p.Ala275Pro mutant decreases ATP1A3 protein expression and Na⁺/K⁺-ATPase activity. …”

Atomic charge differences among IMMS-TLR8 interacting atoms under bound and unbound conditions. by Carlos Kubli-Garfias (310635)

“…<p>Most of the IMMS atoms (left panel) were polarized by the binding process, increasing and decreasing their charge values. Thus, N3, N5 and N11 polar pharmacophore atoms, along with C4 and C5a, showed a high polarization characteristic. …”

Total anopheline captures by trapping-night before and after intervention by treatment arm (A) and by village (B), ZAIVE trial, 2019, Central Vietnam. by Estee Y. Cramer (18462398)

a: Percentage distribution of unmet need for family planning by background characteristics of currently married women (15–49) Nigeria DHS 2008–2018. by Funmilola Folasade Oyinlola (19321601)

Effects of HWHF on (A & B) gut perfusion, (C) intestinal disaccharidase enzyme activity and, (D) GI motility in high fat fed rats. by Prawej Ansari (12191266)

Virucidal activity of LA, SCFA, and succinic acid combinations associated with an optimal vaginal microbiota or BV, representing a non-optimal vaginal microbiota. by Muriel Aldunate (22411177)

IL-17+ cell expansion requires Dectin-2 and is relevant in fungal elimination in the early stages of experimental CBM. by Isaque Medeiros Siqueira (3875767)

“…<p>Frequency of IL-17+ T cells is strongly decreased in dLN and footpad of Dectin-2 KO mice (<b>A</b>). …”

Impaired male germline development due to simultaneous loss of RMI2 and RTEL1. by Sarah Röhrig (3228492)

“…<p>(A) By crossing <i>rmi2-2 rtel1-1</i> with wild-type plants (n = 12), practically no seeds could be obtained using pollen from <i>rmi2-2 rtel1-1</i> mutants for crossbreeding. …”

Reduction of Treg population is related to fungus persistence in infected tissue and opposes self-healing in murine experimental CBM. by Isaque Medeiros Siqueira (3875767)

“…<p>Low frequency of active CD4+ T lymphocytes expressing Foxp3 of animals treated with α-CD25 or control isotype (IC) is shown in popliteal lymph node and footpad (<b>A</b>). Frequency of IL-17+ T cells is decreased in dLN of animals treated with αCD25 after 21 and 28 days of infection (<b>B</b>). …”

Galectin‑9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix by Dharma Pally (7216271)

“…Signaling experiments and unbiased quantitative proteomics revealed Galectin-9 induction of Focal Adhesion Kinase activity and S100A4 expression, respectively. FAK inhibition decreased S100A4 mRNA levels. …”

Angpt1 deficiency increased vascular rarefaction after UUO. by Krishnapriya Loganathan (4729575)

“…At 6 and 10 days of UUO, Angpt1KO mice showed a decreased capillary density compared to WT UUO mice. …”

DataSheet_1_Year-round foraging across large spatial scales suggest that bowhead whales have the potential to adapt to climate change.pdf by Sarah M. E. Fortune (4610563)

“…Our findings suggest that, compared to related species (e.g., right whales), bowheads forage at relatively low rates and over a large geographic area throughout the year. This suggests that bowhead whales have the potential to adjust their behaviours (e.g., increased time allocated to feeding) and shift their distributions (e.g., occupy higher latitude foraging grounds) to adapt to climate-change induced environmental conditions. …”

The SsdC mutant is defective in both germination and heat-resistance. by Johana Luhur (9767765)

“…<p><b>(A)</b> Phase-contrast micrographs of heat-treated (80°C, 20 min) wild-type (bAT87, WT) and Δ<i>ssdC</i> (bJL56) spores during a germination and outgrowth time-course in nutrient-rich media (LB). …”

Cannabidiol effects on behaviour and immune gene expression in zebrafish (<i>Danio rerio</i>) by Hannah M. Jensen (5574980)

“…CDB treatment of zebrafish for 30 min affected mobility of the fish by decreasing swimming speed and swimming distance. In addition, out of 23 immune related genes studied it was shown that expression of two genes <i>il1b</i> and <i>il17a/f2</i> were up-regulated and four genes, <i>tgfba</i>, <i>ighm</i>, <i>cd4-1</i>, and <i>s100a10b</i> were significantly down-regulated following CBD treatment. …”

Experimental and Theoretical Studies on the Platinum-Mediated Selective C(sp)–Si Bond Cleavage of Alkynylsilanes by Yasuhiro Okuda (1591588)

“…A series of <i>cis</i>-alkynyl­(silyl)­platinum­(II) complexes was prepared via the chemoselective C­(sp)–Si bond cleavage of alkynylsilanes by a platinum(0) complex ligated with the P–N hemilabile bidentate ligand. …”

HDAC2-activated gene targets. by Priyanka Somanath (4495033)

“…<p><b>(A)</b> qPCR validation of candidate targets of HDAC2 activation as determined by RNA-seq. …”

Fig 4 - by Hyun-Jun Kim (1561153)

“…<p>A) qPCR analysis of <i>Pax7</i>, <i>Myf5</i>, <i>Myod</i>, <i>Myog</i> and <i>Myh2</i> expression in differentiating C2C12 myoblasts treated with 150 nM, 300 nM or 600 nM Ni for 24 h. * = <i>p</i><0.05, ** = <i>p</i><0.01 and *** = <i>p</i><0.001 indicate significantly increased or decreased expression compared to untreated myoblasts. …”

VPS34 inhibition depletes intracellular iron by blocking iron uptake through enhanced degradation of TFR and excess iron rescues the growth defect in RKO cells. by Marek J. Kobylarz (9292599)

“…Oligomycin (Oligo) inhibits ATP synthase (Complex V) and decreases OCR; FCCP uncouples oxidative phosphorylation and increases OCR; and rotenone/antimycin A (ROT & AA) inhibits Complex I and III, respectively and decreases OCR. …”

Brassinosteroid Regulates 3‑Hydroxy-3-methylglutaryl CoA Reductase to Promote Grape Fruit Development by Ting Zheng (608653)

“…BRs can negatively regulate the expression of <i>VvHMGR</i>, a key gene involved in the mevalonate (MVA) pathway, and reduce the activity of 3-hydroxy-3-methylglutaryl CoA reductase (HMGR). …”