Comparison of oral versus parenteral methotrexate in the treatment of rheumatoid arthritis: A meta-analysis by Andreea M. Bujor (7354679)

“…We propose that parenteral MTX is more effective than weekly oral MTX; its widespread use may lead to better control of disease and a decrease in demand for biologic agents.</p></div>…”

Table1_Furosemide in pediatric intensive care: a retrospective cohort analysis.docx by Melany Gaetani (17791646)

“…Multivariable regression analysis showed no statistically significant decrease in adjusted mortality for patients who received furosemide injections compared to furosemide infusions (aOR 1.20, CI 0.76–1.89).…”

Ginseng and Ginkgo Biloba Effects on Cognition as Modulated by Cardiovascular Reactivity: A Randomised Trial by Derek Ong Lai Teik (2552377)

“…Here, we tested whether cardiovascular reactivity to a task is associated with cognitive improvement.…”

Exogenous <i>miR-146a</i> expression enhances OSCC oncogenicity. by Pei-Shi Hung (489732)

“…Lower, TNFα treatment up-regulates <i>miR-146a</i> expression in OSCC cells. (B) The OSCC cell subclones show an increase in <i>miR-146a</i> expression (Upper), an increase in <i>miR-146a</i> activity and a decrease in NFκB activity (Lower). …”

RSA results across a broader frequency band (0.1–150 Hz). by Pengcheng Lv (7609706)

“…<p><b>(A)</b> For the translation epochs from good trials, the similarity of Same Context was significantly greater than the similarity of Different Context in HC. …”

Hydralazine treatment results in a reduction in tumor blood flow within 15 minutes. by Kate M. Bailey (678043)

“…Representative diagrams showing a decrease in tumor blood flow following hydralazine treatment. …”

Alterations in Peripheral and Central Components of the Auditory Brainstem Response: A Neural Assay of Tinnitus by Andrea S. Lowe (693855)

“…A significant decrease in this ratio (i.e. recovery) was seen only at 16 kHz for P1, indicating the presence of tinnitus near this frequency. …”

A reverse screen identifies mutants with altered mucoviscosity and capsule levels in KPPR1. by Laura A. Mike (543758)

“…<p>Strains reported to have reduced or increased buoyancy were revived from the ordered KPPR1 transposon library. (A, C) The amount of capsule produced by each mutant was quantified by measuring uronic acid content and normalized to the OD₆₀₀. …”

Socially Anxious and Confident Men Interact with a Forward Virtual Woman: An Experimental Study by Xueni Pan (172903)

“…Comparing pre- and post-questionnaire anxiety scores there was no change for the more confident participants but a significant decrease in average score amongst the anxious group. …”

The impact of a chest tube management protocol on the outcome of trauma patients with tube thoracostomy by EMANUELLE MARIA SÁVIO DE ABREU (10458961)

“…Antimicrobial prophylaxis was linked to a significant decrease (p<0.05) in retained hemothoraces, despite no significant (p<0.10) reductions in empyema and surgical site infections. …”

Image_5_A Population of M2 Macrophages Associated With Bone Formation.tif by Elizabeth Olmsted-Davis (11552029)

“…To confirm that these are M2 macrophages, mice received lipopolysacheride (LPS), which induces proinflammation and M1 macrophages. The results showed a significant decrease in this specific population and bone formation, suggesting an essential role for M2 macrophages in the production of bone. …”

Fabrication and Hemocompatibility Evaluation of a Robust Honeycomb Nanostructure on Medical Pure Titanium Surface by Jing Zhang (23775)

“…Thrombosis induced by blood-contacting medical devices is still a major clinical problem, resulting in some serious complications such as infarction, irreversible tissue damage, and even death. …”

A Randomized, Crossover Study to Evaluate the Pharmacokinetics of Amantadine and Oseltamivir Administered Alone and in Combination by Dennis Morrison (272746)

“…Among the therapies considered for use in pandemic influenza is the co-administration of ion channel and neuraminidase inhibitors, both to potentially increase efficacy as well as to decrease the emergence of resistant isolates. To better understand the potential for drug interactions, a cross-over, randomized, open-label trial was conducted with amantadine, 100 mg po bid, and oseltamivir, 75 mg po bid, given alone or in combination for 5 days. …”

Genome Information of <i>Methylobacterium oryzae</i>, a Plant-Probiotic Methylotroph in the Phyllosphere by Min-Jung Kwak (628456)

“…To gain insights into the life style at the phyllosphere and the genetic bases of plant growth promotion, we determined and analyzed the complete genome sequence of <i>Methylobacterium oryzae</i> CBMB20^T, a strain isolated from rice stem. The genome consists of a 6.29-Mb chromosome and four plasmids, designated as pMOC1 to pMOC4. …”

Identification and Functional Validation of Caldesmon as a Potential Gastric Cancer Metastasis-associated Protein by Qian Hou (672015)

“…Finally, knockdown of caldesmon using siRNA in AGS and FU97 gastric cancer cells resulted in an increase in cell migration and invasion, while the overexpression of caldesmon in AZ521 cells led to a decrease in cell migration and invasion. This study has thus established the potential role of caldesmon in gastric cancer metastasis, and further functional studies are underway to delineate the underlying mechanism of action of this protein.…”

A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas by Patricia L. M Dahia (59492)

“…The oxidoreductase defect, not previously detected in <em>VHL</em>-null tumors, is explained by suppression of the SDHB protein, a component of mitochondrial complex II. The decrease in SDHB is also noted in tumors with <em>SDHD</em> mutations. …”

Impacts of Tree Rows on Grassland Birds and Potential Nest Predators: A Removal Experiment by Kevin S. Ellison (397271)

“…Because of gains in habitat, increased use by birds, greater production of young, and the effective removal of woodland-associated predators, tree row removal, where appropriate based on the predator community, can be a beneficial management action for conserving grassland birds and improving fragmented and degraded grassland ecosystems.…”

A reconnaissance provenance study of Triassic–Jurassic clastic rocks of the Russian Barents Sea by Andrey K. Khudoley (7352681)

“…The number of Palaeoproterozoic and Archean grains is very small and becomes significant only in a few Jurassic samples. ε_Nd(t) values gradually decrease from −1.5 to +2.5 in Lower Triassic rocks, to −2.0 to −8.2 in Jurassic rocks, suggesting an increasing influence of ancient metamorphic basement erosion in the younger Jurassic rocks. …”

A Role for PP1/NIPP1 in Steering Migration of Human Cancer Cells by Cristina Martin-Granados (151101)

“…Conversely, the inducible expression of NIPP1 switched the directional response of HeLa cells from cathodal to slightly anodal in a PP1-dependent manner. Remarkably, induction of a hyperactive PP1/NIPP1 holoenzyme, further shifted directional migration towards the anode. …”

Environmental DNA can act as a biodiversity barometer of anthropogenic pressures in coastal ecosystems by Joseph DiBattista (3813505)

“…This change in richness coincides with compositional changes, a decrease in connectedness among taxa, an increase in fragmentation of taxon co-occurrence networks, and a shift in indicator taxa. …”