A Genome-Wide Screen for Modifiers of [<i>PSI</i>⁺] Induction by Jens Tyedmers (220526)

“…Some gene deletions cause a clear reduction of toxicity (decreased [<i>PSI</i>⁺] induction, exemplified here by <i>hsp104</i>Δ), whereas others further enhance toxicity (increased [<i>PSI</i>⁺] induction, exemplified by <i>hac1</i>Δ).…”

Image_5_Amelioration of Endotoxemia by a Synthetic Analog of Omega-3 Epoxyeicosanoids.jpeg by Akira Shikuma (12130158)

“…Overall survival significantly improved following preventative EEQ-A administration along with decreased transcript level of pro-inflammatory cytokines. …”

Coordinating Environmental Genomics and Geochemistry Reveals Metabolic Transitions in a Hot Spring Ecosystem by Wesley D. Swingley (160502)

“…This channel acts as a >22 m gradient of decreasing temperature, increasing dissolved oxygen, and changing availability of biologically important chemical species, such as those containing nitrogen and sulfur. …”

Table_1_Body composition and testosterone in men: a Mendelian randomization study.xlsx by Yoshihiro Ikehata (15993890)

“…Background<p>Testosterone is an essential sex hormone that plays a vital role in the overall health and development of males. …”

A coarse-grained sensitivity analysis of the effect of drug-induced resistance on treatment outcome. by Erin Angelini (13149930)

“…<p>The parameters given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010319#pcbi.1010319.s006" target="_blank">S1 Table</a> are held fixed, while the EC50 and efficacy of resistance induction are varied in the above four cases. …”

Table_3_Impact of educational interventions on the prevention of influenza: A systematic review.docx by Mohammad Javad Nasiri (7500002)

“…Introduction<p>Seasonal influenza, a contagious viral disease affecting the upper respiratory tract, circulates annually, causing considerable morbidity and mortality. …”

Data_Sheet_1_The Effects of Corticosteroids on the Respiratory Microbiome: A Systematic Review.docx by Julia E. Hartmann (10279604)

“…Microbiome diversity increased with corticosteroids at least transiently in three studies and decreased in one study. The effects of corticosteroids on the composition of the respiratory microbiome were significant but without a clear shared direction. …”

Image_2_Amelioration of Endotoxemia by a Synthetic Analog of Omega-3 Epoxyeicosanoids.jpeg by Akira Shikuma (12130158)

“…Overall survival significantly improved following preventative EEQ-A administration along with decreased transcript level of pro-inflammatory cytokines. …”

Platelet-Rich Plasma in Young and Elderly Humans Exhibits a Different Proteomic Profile by Zhitong Jiang (9025358)

“…Furthermore, a comprehensive understanding of the specific impact of aging on PRP requires a systematic investigation. …”

Analysis of apoptosis and protein changes after treatment with a specific caspase-3 inhibitor. by Li Wang (15202)

“…Western blot analysis of RhoGDIα, caspase-3, and PARP protein levels. (a) Cells subjected to 20% cyclic strain in the presence of z-DEVD-FMK exhibited decreased cleavage of PARP compared with the level in the 20% cyclic strain group in the absence of z-DEVD-FMK, while the protein levels of RhoGDIα and 19-kDa caspase-3 did not differ significantly. …”

Hepatoprotective Effect of MMP-19 Deficiency in a Mouse Model of Chronic Liver Fibrosis by Marketa Jirouskova (128135)

“…We show that loss of MMP-19 was beneficial during liver injury, as plasma ALT and AST levels, deposition of fibrillar collagen, and phosphorylation of SMAD3, a TGF-ß1 signaling molecule, were all significantly lower in MMP19KO mice. …”

Figure 2 from PELP1 Is a Novel Therapeutic Target in Hepatocellular Carcinoma by Khaled Mohamed Nassar (19810317)

“…<p><i>PELP1</i>-KD/SMIP34 treatment decreased cell viability, clonogenicity, and invasiveness of HCC cells. …”

DataSheet1_A Multiscale Spatiotemporal Approach for Smallholder Irrigation Detection.pdf by Terence Conlon (12415306)

“…<p>In presenting an irrigation detection methodology that leverages multiscale satellite imagery of vegetation abundance, this paper introduces a process to supplement limited ground-collected labels and ensure classifier applicability in an area of interest. …”

(A) Profile of mean-squared error of elastic-net regression for various values of lambda. by Chan C. Whiting (773096)

“…<p>For a range of lambdas, an elastic-net regression is fit using 10-fold cross-validation. …”

Understanding Regiodivergence in a Pd(II)-Mediated Site-Selective C–H Alkynylation by Kenji Usui (1748389)

“…TIPS alkyne <i>bromides</i> react selectively with the six-membered palladacycle (from δ-palladation) through a migratory insertion pathway. The observed δ-selectivity in this case is attributed to decreased ring strain in the migratory insertion transition state with the six-membered palladacycle. …”

A Multicopper Oxidase-Related Protein Is Essential for Insect Viability, Longevity and Ovary Development by Zeyu Peng (647173)

“…During our studies of insect MCOs, we discovered a gene that we named multicopper oxidase-related protein (MCORP). …”

New Insights into Fish Swimming: A Proteomic and Isotopic Approach in Gilthead Sea Bream by Miguel Martin-Perez (1624459)

“…Moderate exercise enhances fish growth, although underlying physiological mechanisms are not fully known. Here we performed a proteomic and metabolic study in white (WM) and red (RM) muscle of gilthead sea bream juveniles swimming at 1.5 body lengths per second. …”

Accuracy of Genomic Selection in a Rice Synthetic Population Developed for Recurrent Selection Breeding by Cécile Grenier (788754)

“…The effect of kinship between the training and validation populations was tested in an additional set of 840 cross validation experiments with a single genomic prediction model. LD was high (average r² = 0.59 at 25 kb) and decreased slowly, distribution of allele frequencies at individual loci was markedly skewed toward unbalanced frequencies (MAF average value 15.2% and median 9.6%), and differentiation between the four synthetic populations was low (F_ST ≤0.06). …”

Supplementary Material for: Clinical and Experimental Insights into the Role of NETosis in IgA Nephropathy Pathogenesis by figshare admin karger (2628495)

“…Serum levels of NETosis markers—citrullinated histone H3 (CitH3), myeloperoxidase (MPO), and neutrophil elastase (NE)—were elevated in IgAN patients, with CitH3 levels correlating with Gd-IgA1. Inhibiting NETosis with GSK484 reduced CitH3 levels in IgAN mice and improved clinical outcomes, including decreased proteinuria and increased serum albumin. …”

Effects of resistance training on postural control in Parkinson’s disease: a randomized controlled trial by Janini CHEN (12686145)

“…Methods: Seventy-four patients were randomly assigned to a three-month RT intervention consisting of using weightlifting machines at a gym (gym group) or RT consisting of using free weights and elastic bands (freew group), or to a control group. …”