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47781
Supplementary Material for: Effects of exercise during chemo- or radiotherapy on immune markers – a systematic review
Published 2023“…The majority of markers was unaltered, but observed effects included a suppressive effect of exercise during radiotherapy on some pro-inflammatory markers, a preserving effect of exercise during chemotherapy on NK cell degranulation and cytotoxicity, a protective effect on the decrease in thrombocytes during chemotherapy, and a positive effect of exercise during chemotherapy on IgA. …”
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47782
αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor
Published 2015“…Through interaction αPIX sequesters c-Cbl from EGFR and this results in reduced EGFR ubiquitination and decreased EGFR degradation upon EGF treatment. However, quantitatively more decisive for cellular EGFR distribution than impaired EGFR degradation is a strong stimulating effect of αPIX on EGFR recycling to the cell surface. …”
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47783
The coexistence of traditional medicine and biomedicine: A study with local health experts in two Brazilian regions
Published 2017“…In the maroon communities, a greater number of specialists thought there was a decrease in the number and demand for healers, as well as the use of medicinal plants, due to changes in traditional livelihoods, since they are located in a region where the effects of the modernization were more intense. …”
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47784
A General Strategy for Biocompatible, High-Effective Upconversion Nanocapsules Based on Triplet–Triplet Annihilation
Published 2013“…A general strategy for constructing high-effective upconversion nanocapsules based on triplet–triplet annihilation (TTA) was developed by loading both sensitizer and annihilator into BSA–dextran stabilized oil droplets. …”
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47785
Table1_Thyroid dysfunction and sarcopenia: a two-sample Mendelian randomization study.docx
Published 2024“…</p>Results<p>The MR analysis indicated that hyperthyroidism could lead to a significant decrease in ALM in the extremities (OR = 1.03; 95% CI = 1.02 to 1.05; P < 0.001). …”
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47786
DataSheet1_A Zebrafish Model of Neurotoxicity by Binge-Like Methamphetamine Exposure.PDF
Published 2021“…After an initial testing at 20 and 40 mg/L for 48 h, the later METH concentration was selected for developing the model and the effects on the brain monoaminergic profile, locomotor, anxiety-like and social behaviors as well as on the expression of key genes of the catecholaminergic system were determined. A concentration- and time-dependent decrease in the brain levels of dopamine (DA), norepinephrine (NE) and serotonin (5-HT) was found in METH-exposed fish. …”
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47787
Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome
Published 2015“…After viral infection, the number of unique self-peptides eluted significantly decreased compared to uninfected cells, paralleled by a decrease in the number of source proteins. …”
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47788
Doses of enzyme complex in a high-energy diet on performance and carcass traits of feedlot steers
Published 2018“…Each gram of product added to the diet led to a decrease of 0.0818 kg in daily dry matter intake (DMI), whereas fat thickness at the ribs and at the hindquarter increased by 0.3850 and 0.080 mm, respectively. …”
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47789
Image_1_Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation.jpg
Published 2020“…Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a promising pharmacological target, and selective inhibitors of NEU1 are therefore needed to better understand the biological functions of this sialidase. …”
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47790
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment
Published 2021“…The <b>CHBC</b>–GPR17 interaction leads to a rapid decrease of cAMP and Ca<sup>2+</sup>. <b>CHBC</b> exhibits the cytotoxicity effect on GBM cells in a dose-dependent manner with an IC<sub>50</sub> of 85 μM, whereas the known agonist MDL29,951 showed a negligible effect. …”
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47791
Nitrogen addition increases aboveground silicon and phytolith concentrations in understory plants of a tropical forest
Published 2021“…The significant accumulation of Si in the leaves and the unaltered plant-available Si concentrations in the soil were associated with enhanced plant Si uptake and decreased soil phytolith return due to increased phosphorus <a>(P) limitation</a>, soil acidification, and decreased leaf C:N ratios caused by N addition.…”
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47792
Outcomes of segmental femoral artery pseudoaneurysm in patients with Behçet’s disease: a single center’s experience
Published 2019“…Objectives To clarify the importance of profunda femoris artery in BD pseudoaneurysm, and present a new method for identifying healthy segments for anastomosis. …”
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47793
Statins Have No Additional Benefit for Pulmonary Hypertension: A Meta-Analysis of Randomized Controlled Trials
Published 2016“…<div><p>Objectives</p><p>We performed a meta-analysis to explore the effects of adding statins to standard treatment on adult patients of pulmonary hypertension (PH).…”
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47794
Increased Immunogenicity and Protective Efficacy of Influenza M2e Fused to a Tetramerizing Protein
Published 2012“…Most importantly, vaccination with M2e-NSP4 caused a significant decrease in lung virus load early after challenge with influenza A virus and maintained its efficacy against a lethal challenge even at very low vaccine doses. …”
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47795
BioMAP biomarker profiles for (A) ruxolotinib, (B) fedratinib, (C) momelotinib, and (D) pacritinib.
Published 2019“…Biomarker key activities are described as modulated if these activities increase in some systems, but decrease in others. Cytotoxicity is indicated on the profile plot by a thin black arrow above the X-axis, and antiproliferative effects are indicated by a thick grey arrow. …”
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47796
A comprehensive meta-analysis on evidence of Mediterranean diet and cardiovascular disease: Are individual components equal?
Published 2017“…We performed a meta-analysis to explore the association in prospective studies and randomized control trials (RCTs) between Mediterranean diet adherence and CVD incidence and mortality. …”
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47797
PrA inhibited DC maturation responding to LPS and diminished DC-mediated T cell allostimulation.
Published 2013“…The highest dose induced a significant decrease in viable DC count, so only 5 nM and 20 nM were used in subsequent experiments. …”
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47798
A Tale of Two Morphs: Modeling Pollen Transfer, Magic Traits, and Reproductive Isolation in Parapatry
Published 2014“…In a different pollination scenario, however, precise pollen transfer causes a decrease in adaptive divergence by promoting asymmetric gene flow. …”
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47799
Molecular dynamics simulation of the heart type fatty acid binding protein in a crystal environment
Published 2020“…Restraining one-third of <i>Cα</i> atoms based on experimental B-factors produce lower B-factors than simulations without restraints, showing that the position restraint of the atoms with the lowest experimental B-factor is a good strategy to maintain the geometry of the crystal with an obvious decrease in the degrees of motion of the protein. …”
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47800
Identification of <i>Abhd2</i> as a driver of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in liver.
Published 2023“…<p>(<b>A</b>) LOD profiles for <i>Abhd2</i> expression and abundance of several phospholipids in liver identify a common quantitative trait locus (QTL) at ~79 Mbp on chromosome 7. …”