Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer by George M. Philips (206900)

“…<div><h3>Objective</h3><p>Chronic fibrosing liver injury is a major risk factor for hepatocarcinogenesis in humans. …”

Association between ultraviolet radiation exposure dose and cataract in Han people living in China and Taiwan: a cross-sectional study by Hisanori Miyashita (6587044)

“…The cumulative ocular UV exposure (COUV) was calculated. A logistic regression analysis was used for multivariate analysis.…”

Image_1_mTOR pathway as a potential therapeutic target for cancer stem cells in canine mammary carcinoma.tiff by Masaki Michishita (4100770)

“…In mice transplanted with CTBp-derived spheres, everolimus treatment significantly decreased tumor volume compared to control. These results reveal that the mTOR signaling pathway may be a potential to be a therapeutic target in both cancer cells and CSCs. …”

Image_1_Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury.tiff by Alfonso Rubio-Navarro (503533)

“…Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression of antioxidant proteins. …”

Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions by Hideaki Nakamura (402108)

“…<div><p>Tumor hypoxia contributes to a biologically aggressive phenotype and therapeutic resistance. …”

DataSheet_1_The Specific Alteration of Gut Microbiota in Diabetic Kidney Diseases—A Systematic Review and Meta-Analysis.docx by Yuwei Wang (178411)

“…Compared to HC, the bacterial richness of patients with DKD was significantly decreased, and the diversity indexes were decreased but not statistically, companying with a distinct beta diversity. …”

DataSheet1_Ceramide Aminoethylphosphonate as a New Molecular Target for Pore-Forming Aegerolysin-Based Protein Complexes.PDF by Teresa Balbi (8710875)

“…In Mytilus haemocytes, short term exposure (max. 1 h) to the OlyA6/PlyB mixture induced lysosomal membrane destabilization, decreased phagocytic activity, increased Annexin V binding and oxyradical production, and decreased levels of reduced glutathione, indicating rapid damage of endo-lysosomal and plasma membranes and oxidative stress. …”

Table_1_The Clustering Analysis of Time Properties in Patients With Cerebral Small Vessel Disease: A Dynamic Connectivity Study.docx by Wenwen Yin (1877125)

“…The changes in the DFC are associated with altered cognition in CSVD. This study provides a better explanation of the potential mechanism of CSVD patients with cognitive impairment from the perspective of DFC.…”

Image4_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. …”

Image9_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. …”

Image11_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. …”

Image8_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.TIF by Leonardo Y. Tanaka (18306715)

“…The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. …”

Table3_Causal analysis of the gut microbiota in differentiated thyroid carcinoma: a two-sample Mendelian randomization study.XLSX by Zheng Quan (17624256)

“…</p><p>Results: IVW analysis revealed a dual role of the GM in thyroid carcinoma. The phylum Actinobacteria (OR, 0.249 [95% CI, 0.121–0.515]; p < 0.001) was associated with a decreased risk of DTC. …”

Trend of lipid and thyroid function tests in adults without overt thyroid diseases: A cohort from Tehran thyroid study by Salma Ahi (6707522)

“…</p><p>Results</p><p>In every four years of assessments, there were significant decreases in levels of all lipid parameters (all Ps <0.001) except for HDL-C, in which a decrescendo-crescendo trend was observed. …”

Table4_Causal analysis of the gut microbiota in differentiated thyroid carcinoma: a two-sample Mendelian randomization study.DOCX by Zheng Quan (17624256)

“…</p><p>Results: IVW analysis revealed a dual role of the GM in thyroid carcinoma. The phylum Actinobacteria (OR, 0.249 [95% CI, 0.121–0.515]; p < 0.001) was associated with a decreased risk of DTC. …”

A diet supplemented with hazelnut skin changes the microbial community composition and the biohydrogenation pattern of linoleic acid in the rumen of growing lambs by Matteo Daghio (10718532)

“…The results suggest that the relative abundance of microorganisms correlated to C18:1 <i>t</i>10 production in the rumen of animals fed a concentrate-based diet can be reduced by the administration of hazelnut skin.Highlights</p><p>A diet with hazelnut skin affected the microbial community in the rumen of lambs</p><p>The relative abundance of the genus <i>Dialister</i> decreased with hazelnut skin</p><p>Administration of hazelnut skin can be a strategy to reduce the C18:1 <i>t</i>10/<i>t</i>11 ratio</p><p></p> <p>A diet with hazelnut skin affected the microbial community in the rumen of lambs</p> <p>The relative abundance of the genus <i>Dialister</i> decreased with hazelnut skin</p> <p>Administration of hazelnut skin can be a strategy to reduce the C18:1 <i>t</i>10/<i>t</i>11 ratio</p>…”

Presentation1_Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.pdf by Leonardo Y. Tanaka (18306715)

“…The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. …”

Table_1_Effects of Ramadan and Non-ramadan Intermittent Fasting on Body Composition: A Systematic Review and Meta-Analysis.pdf by Joana M. Correia (10033139)

“…Conversely, we observed a significant increase in fat-free mass when comparing pre- to post-intervention in a within design fashion (0.306, 95% CI [0.133, 0.48], p = 0.001). …”

Severity and duration of diabetic foot ulcer (DFU) before seeking care as predictors of healing time: A retrospective cohort study by Hilde Smith-Strøm (4022894)

“…Patients who were referred to specialist health care by a general practitioner ≥ 52 days after ulcer onset had a 58% (SHR 0.42, CI 0.18–0.98) decreased healing rate compared to patients who were referred earlier, in the adjusted model. …”

Table 1_Evaluating the prognostic relevance of neutrophil-to-lymphocyte ratio in cervical cancer: a systematic review and meta-analysis.docx by Xieyan Zhuang (20467625)

“…</p>Conclusion<p>An elevated NLR prior to treatment demonstrates a strong association with decreased OS and PFS among patients with cervical cancer, underscoring the significance of NLR as a prognostic marker within this population.…”