Video_2_Distinct Mitochondrial Remodeling During Mesoderm Differentiation in a Human-Based Stem Cell Model.MP4 by Sepideh Mostafavi (11561719)

“…Remodeling of mitochondria and metabolism, with the shift from glycolysis to oxidative phosphorylation (OXPHOS), plays a fundamental role in maintaining pluripotency and stem cell fate. …”

Supplementary file 1_Clinical utility of the PBAC score in quantifying treatment response to hysteroscopy: a retrospective observational study.docx by Ömer Faruk Öz (22702202)

“…</p>Results<p>Of the 327 patients included in the study, 91.1% had a baseline PBAC score ≥100, which significantly decreased following hysteroscopy (mean reduction: 393 points; p < .001). …”

Presentation_1_Retroelement Insertion in a CRISPR/Cas9 Editing Site in the Early Embryo Intensifies Genetic Mosaicism.pptx by Jeehyun Jeon (7838141)

“…To understand the earliest events during CRISPR/Cas9 editing and the allelic selection among the progeny of subsequent cell divisions, we inspected in detail the genotypes of 4- and 8-cell embryos and embryonic stem cells (ESCs) after microinjection of a CRISPR toolkit into the zygotes. We found a higher editing frequency in 8-cell embryos than in 4-cell embryos, indicating that the CRISPR/Cas9 activity persisted through the 8-cell stage. …”

Data_Sheet_1_Daily Torpor and Sleep in a Non-human Primate, the Gray Mouse Lemur (Microcebus murinus).docx by Julie Royo (7420463)

“…In many heterothermic species there is a relation between torpor expression and the repartition of the different behavioral states of sleep. …”

Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer’s Mice Model: A Proteomic Study by Xiubo Du (1734001)

“…Se-methylselenocysteine (SMC) is a major selenocompound in selenium (Se) enriched plants and has been found to ameliorate neuropathology and cognitive deficits in triple-transgenic mice model of Alzheimer’s disease (3 × Tg-AD mice). …”

Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer’s Mice Model: A Proteomic Study by Xiubo Du (1734001)

“…Se-methylselenocysteine (SMC) is a major selenocompound in selenium (Se) enriched plants and has been found to ameliorate neuropathology and cognitive deficits in triple-transgenic mice model of Alzheimer’s disease (3 × Tg-AD mice). …”

DataSheet_1_Effective treatment of advanced lung adenocarcinoma with paraneoplastic leukemoid reaction with Lorlatinib: a case report.pdf by Ruiqi Niu (2362630)

“…Background<p>Lorlatinib is a new generation ALK kinase inhibitor. We describe a 52-year-old patient with ALK-positive advanced lung adenocarcinoma who achieved remission after multi-line therapy combined with paraneoplastic leukemoid reaction treated with Lorlatinib.…”

Three unrelated and unexpected amino acids determine the susceptibility of the interface cysteine to a sulfhydryl reagent in the triosephosphate isomerases of two trypanosomes by Selma Díaz-Mazariegos (224283)

“…This study completes a strategy for identifying key residues in the sequences of proteins that can have applications in future protein structure-function studies.…”

Table 1_Case Report: Longitudinal mass cytometry profiling of a patient with disseminated histoplasmosis and secondary hemophagocytic lymphohistiocytosis.docx by Jiaying Zhang (585596)

“…Concurrent immune-metabolic profiling revealed a metabolic shift from glycolysis to lipid oxidation, characterized by decreased expression of GLUT1 and CPT1A and increased expression of CD36. …”

A Near-Infrared-II Fluorescent Nanoprobe Offering Real-Time Tracking of Fenton-Like Reaction for Cancer Chemodynamic Theranostics by Jingwen Sun (116284)

“…Chemodynamic therapy (CDT) utilizing Fenton or Fenton-like reactions to generate cytotoxic hydroxyl radicals by metal ions has become a compelling strategy for cancer treatment. Visualizing intratumoral Fenton or Fenton-like reactions especially at a cellular level in real-time can directly monitor the process of CDT, which is not yet feasible. …”

Table_5_Proteomic analysis of the regulatory networks of ClpX in a model cyanobacterium Synechocystis sp. PCC 6803.xlsx by Yumeng Zhang (3115050)

“…In cyanobacteria, the ClpXP proteolytic complex is regarded as a representative proteolytic system and consists of a hexameric ATPase ClpX and a tetradecameric peptidase ClpP. …”

Image_1_ΔFosB is part of a homeostatic mechanism that protects the epileptic brain from further deterioration.TIF by Jerome Clasadonte (17777424)

“…Furthermore, prolonged inhibition of ΔFosB using a ΔJunD construct to block ΔFosB signaling in a mouse model of Alzheimer’s disease, that exhibits spontaneous recurrent seizures, led to similar findings, with increased neuroinflammation and decreased NPY expression in mossy fibers. …”

Se-Methylselenocysteine (SMC) Improves Cognitive Deficits by Attenuating Synaptic and Metabolic Abnormalities in Alzheimer’s Mice Model: A Proteomic Study by Xiubo Du (1734001)

“…Se-methylselenocysteine (SMC) is a major selenocompound in selenium (Se) enriched plants and has been found to ameliorate neuropathology and cognitive deficits in triple-transgenic mice model of Alzheimer’s disease (3 × Tg-AD mice). …”

Table_1_Novel Compound Heterozygous Mutations in TTI2 Cause Syndromic Intellectual Disability in a Chinese Family.docx by Rongrong Wang (322058)

“…Herein, we identified compound heterozygous mutations in TTI2 using whole-exome sequencing (WES) in a Chinese family with a recessive inheritance pattern of syndromic intellectual disability. …”

Data_Sheet_1_The Water Microbiome Through a Pilot Scale Advanced Treatment Facility for Direct Potable Reuse.PDF by Rose S. Kantor (3744070)

“…We applied high-throughput amplicon sequencing, read-based, assembly-based, and genome-resolved metagenomics, and flow cytometry to investigate the microbial communities present in a pilot-scale advanced water treatment facility. …”

Table_1_Altered resting-state brain activity in functional dyspepsia patients: a coordinate-based meta-analysis.DOCX by Yangke Mao (13951776)

“…Thereafter, the anisotropic effect size signed the differential mapping (AES-SDM) approach that was applied to meta-analyze the aberrant brain activity pattern of FD patients.</p>Results<p>A total of 11 articles with 260 FD patients and 202 healthy controls (HCs) were included. …”

Table_1_Mitochondrial Fusion Potentially Regulates a Metabolic Change in Tibetan Chicken Embryonic Brain During Hypoxia.DOCX by Qiguo Tang (8145771)

“…<p>The Tibetan chickens (Gallus gallus; TBCs) are an indigenous breed found in the Qinghai-Tibet Plateau that are well-adapted to a hypoxic environment. As of now, energy metabolism of the TBCs embryonic brain has been little examined. …”

Insight into monogenetic eruption processes at Pelagatos volcano, Sierra Chichinautzin, Mexico: a combined melt inclusion and physical volcanology study by Julie Roberge (2843384)

“…Discharge of volatile-poor, low-viscosity magma drives early effusive activity along the fissure. Decreasing magma fluxes lead to the clogging of the fissure and the formation of a shallow magma reservoir where degassing and fractional crystallization take place. …”

Presentation_1_KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts.PDF by Kang-Sik Seo (5482199)

“…In this study, we investigated the effects of a novel NAD⁺ modulator, KL1333, in human fibroblasts derived from a human patient with MELAS. …”

Modification of Male Courtship Motivation by Olfactory Habituation via the GABA_A Receptor in <i>Drosophila melanogaster</i> by Shin-Ichiro Tachibana (707681)

“…<div><p>A male-specific component, 11-<i>cis</i>-vaccenyl acetate (cVA) works as an anti-aphrodisiac pheromone in <i>Drosophila melanogaster</i>. …”