The Impact of Nationwide Education Program on Clinical Practice in Sepsis Care and Mortality of Severe Sepsis: A Population-Based Study in Taiwan by Yu-Chun Chen (162910)

“…<div><p>Objectives</p><p>We investigated the effect of a nationwide educational program following surviving sepsis campaign (SSC) guidelines. …”

Proposed circuitry of a Golgi cell-granule cell synapse illustrating the effect of TTX and acute EtOH on GABAergic transmission. by Marvin R. Diaz (286193)

“…(B) In the presence of TTX, GoC firing ceases, allowing only quantal release of GABA into the synaptic space and significantly reducing phasic GABA_AR sIPSCs. Extrasynaptic GABA levels are also reduced, thereby decreasing CGN-I_tonic. …”

Supplementary file 1_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx by Yi-Chang Zhao (14080107)

“…Adverse reactions showed a non-significant reduction (RR = 0.65; 95% CI: 0.38–1.11). …”

Charged and Hydrophobic Surfaces on the A Chain of Shiga-Like Toxin 1 Recognize the C-Terminal Domain of Ribosomal Stalk Proteins by Andrew J. McCluskey (183382)

“…Based on these 2 peptide motifs, SLT-1 A₁ variants were generated that displayed decreased affinities for the stalk protein C-terminus and also correlated with reduced ribosome-inactivating activities in relation to the wild-type A₁ chain. …”

SALL4, a Stem Cell Factor, Affects the Side Population by Regulation of the ATP-Binding Cassette Drug Transport Genes by Ha-Won Jeong (224496)

“…<div><p>Our previous work shows that the stem cell factor SALL4 plays a central role in embryonic and leukemic stem cells. …”

Image_2_Transcriptomic Changes of Piscirickettsia salmonis During Intracellular Growth in a Salmon Macrophage-Like Cell Line.pdf by Alejandro Zúñiga (8273802)

“…The results indicated that in comparison to uninfected SHK-1 cells, infection significantly decreased cell viability after 10 days along with a significant increment of P. salmonis genome equivalents. …”

Iodine supplementation of lactating women and assessment of infant visual information processing and maternal and infant thyroid function: A randomized trial by Tafere Gebreegziabher (4430311)

“…Mothers were randomly assigned either to receive a potassium iodide capsule (225 μg iodine) daily for 26 weeks or iodized salt weekly for 26 weeks. …”

Table_1_Cost-Effectiveness of Public Health Measures to Control COVID-19 in China: A Microsimulation Modeling Study.DOCX by Qiang Wang (32383)

“…<p>This study aimed to assess the cost-effectiveness of various public health measures in dealing with coronavirus disease 2019 (COVID-19) in China. A stochastic agent-based model was used to simulate the progress of the COVID-19 outbreak in scenario I (imported one case) and scenario II (imported four cases) with a series of public health measures. …”

Table1_Identification and Validation of a Novel Pyroptosis-Related Gene Signature for Prognosis Prediction in Soft Tissue Sarcoma.DOCX by Lin Qi (128224)

“…In conclusion, this study provided a comprehensive overview of PRGs in STS and the potential role in prognosis, which could be an important direction for future studies.…”

Characterization of a non-nudix pyrophosphatase points to interplay between flavin and NAD(H) homeostasis in <i>Saccharomyces cerevisiae</i> by Joseph H. Lynch (5394944)

“…In addition, we report that the deletion of <i>fpy1</i> intensifies the FMN-dependence of null mutants of the riboflavin kinase Fmn1p, demonstrate that <i>fpy1</i> mutation abolishes the decreased fitness resulting from the deletion of the <i>flx1</i> ORF, and offer a possible mechanism for the genetic interplay between <i>fpy1</i>, <i>flx1</i> and <i>fmn1</i>.…”

Table_3_Predicting Disease Progression and Mortality in Aortic Stenosis: A Systematic Review of Imaging Biomarkers and Meta-Analysis.docx by Alain Nchimi (798171)

Data_Sheet_1_A Potential Biocontrol Agent Streptomycesviolaceusniger AC12AB for Managing Potato Common Scab.docx by Arslan Sarwar (619948)

“…Therefore, plant growth promoting S. violaceusniger AC12AB could provide a dual benefit by decreasing PCS disease severity and increasing potato yield as an effective and inexpensive alternative strategy to manage this disease.…”

DataSheet_1_Gut microbiota composition in travellers is associated with faecal lipocalin-2, a mediator of gut inflammation.docx by Javier Gandasegui (778298)

“…Differential abundance (DA) testing highlighted a microbial profile tied to high LCN2 levels, marked by increased Proteobacteria and Escherichia-Shigella, and decreased Firmicutes, notably Oscillospiraceae. …”

Poly(caprolactone)-Based Coatings on 3D-Printed Biodegradable Implants: A Novel Strategy to Prolong Delivery of Hydrophilic Drugs by Sarah A. Stewart (9198984)

“…Implants could be specifically developed in order to match the specific release rate required for a number of drugs for a wide range of conditions.…”

Image3_Identification and Validation of a Novel Pyroptosis-Related Gene Signature for Prognosis Prediction in Soft Tissue Sarcoma.JPEG by Lin Qi (128224)

“…In conclusion, this study provided a comprehensive overview of PRGs in STS and the potential role in prognosis, which could be an important direction for future studies.…”

Supplementary Material for: A Placebo-Controlled, Randomized Trial of Enarodustat in Patients with Chronic Kidney Disease Followed by Long-Term Trial by Akizawa T. (3588626)

“…<b><i>Background:</i></b> Enarodustat (JTZ-951) is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor that mimics adaptive responses to hypoxic conditions and may provide a new therapeutic approach for managing anemia in patients with chronic kidney disease (CKD). …”

Table 1_Factors affecting health-seeking behavior in sports climbers in Metro Manila: a cross-sectional study.docx by Danyelle Jay T. Cruz (20772668)

“…</p>Discussion<p>Climbers in Metro Manila have a decreased tendency to engage in health-seeking behavior. …”

The effect of dexmedetomidine on expression of neuronal nitric oxide synthase in spinal dorsal cord in a rat model with chronic neuropathic pain by Jun Pang (591243)

“…Nitric oxide produced by neuronal nitric oxide synthase (nNOS) in the spinal dorsal cord might serve a predominant role in regulating the algesia of neuropathic pain. …”

Video_2_Reduced menthol sensitivity in a prodromal Parkinson’s disease model induced by intranasal rotenone treatment.MP4 by Hajime Sato (76981)

“…<p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor symptoms, and it is associated with several prodromal non-motor symptoms, including an impaired sense of smell, taste and touch. …”

Image_5_Transcriptomic Changes of Piscirickettsia salmonis During Intracellular Growth in a Salmon Macrophage-Like Cell Line.pdf by Alejandro Zúñiga (8273802)

“…The results indicated that in comparison to uninfected SHK-1 cells, infection significantly decreased cell viability after 10 days along with a significant increment of P. salmonis genome equivalents. …”