The Impact of a One-Dose versus Two-Dose Oral Cholera Vaccine Regimen in Outbreak Settings: A Modeling Study by Andrew S. Azman (121645)

“…<div><p>Background</p><p>In 2013, a stockpile of oral cholera vaccine (OCV) was created for use in outbreak response, but vaccine availability remains severely limited. …”

Image_1_Burns Impair Blood-Brain Barrier and Mesenchymal Stem Cells Can Reverse the Process in Mice.pdf by Jie Yang (121778)

“…These results suggest that burns increase BBB permeability through both paracellular pathway and transcytosis, the potential mechanism of which might be through increasing IL-6 and IL-1β levels and decreasing Mfsd2a level, and appropriate treatment with UC-MSCs can reverse these effects and protect the integrity of BBB after burns.…”

Housing conditions affected acquisition of SRM in female rats (mean±SEM): A) Females from group housing displayed a significant decrease in the SIT during the second 2 min encounter (A2, empty bars) compared to the first (A1, gray bars) when encounters were separated by 30 or 120 min. by Hadar Shahar-Gold (283031)

Projected annual CH₄ (A) and N₂O (B) emissions (Mt/yr) by 2050, based on FAO no-mitigation (increasing) and mitigation (decreasing) scenarios, and on a constant emission scenario. by Fabio Correddu (12501799)

“…<p>Projected annual CH₄ (A) and N₂O (B) emissions (Mt/yr) by 2050, based on FAO no-mitigation (increasing) and mitigation (decreasing) scenarios, and on a constant emission scenario.…”

CPTA-glycine derivative, forming a hippurane-type spacer molecule, demonstrates a significantly decreased uptake in kidney at 1, 4 h p.i. and 4 h p.i. blocked with an excess of BN peptide. by Hanwen Zhang (307516)

“…<p>CPTA-glycine derivative, forming a hippurane-type spacer molecule, demonstrates a significantly decreased uptake in kidney at 1, 4 h p.i. and 4 h p.i. blocked with an excess of BN peptide.…”

Table_1_A T3SS Regulator Mutant HY9901 ΔaraC of Vibrio alginolyticus Decreased the Expression of HopPmaJ and Provided Protection to Danio rerio as a Live-Attenuated Vaccine.xls by Junlin Wang (4029803)

“…The swimming ability of ΔaraC decreased and exhibited a 2,600 times reduction in virulence to zebrafish. …”

The percentage of cells with protein aggregates cotransfected with αA- and αB-crystallin or R120G αB-crystallin (αBM) genes by Bing-Fen Liu (81305)

“…</p><p></p> The x-axis labels are either RED-αB- or the pairs of GFP-αA- and RED-αB-crystallin. A four-fold decrease of cells with protein aggregates was observed for cotransfection of αA- and αB-crystallin (the asterisk indicates a p=0.006), but only about a 1.5 fold decrease for cotransfection of αA- and αBM-crystallin (the double asterisk indicates a p=0.02). …”

Proposed Dyrk1A functions in regulating synaptic vesicle endocytosis. by Noriko Murakami (171144)

“…<p>Dyrk1A phosphorylated AP180 in cytosol. The phosphorylated AP180 may decrease its binding affinity to the AP2 complex; we hypothesize here that the decrease in such binding affinity would reduce recruitment of clathrin at the <i>nucleation</i> and <i>invagination</i> sites. …”

Multiple linear regression models (a - p) of environmental response variables regressed against the habitat transformation variables (predictors), given the spatio-temporal covaria... by Matthew S. Bird (522478)

“…To maximise parsimony, covariable subsets were pre-selected for each model using step-wise regression of each response variable on the full list of possible covariables (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0088935#pone-0088935-t001" target="_blank">Table 1</a>). …”

Table_1_Non-linear association between serum spermidine and mild cognitive impairment: Results from a cross-sectional and longitudinal study.DOCX by Jiahui Xu (3156327)

“…Restricted cubic spline models show that there is a non-linear association between SPD and MCI. In line with cross-sectional findings, the longitudinal study showed that a high SPD concentration may indicate a lower risk of MCI [ORs (95% CIs) for the third tertile of 0.62 (0.39, 0.99)].…”

MiR-24 target Trib3 regulates hematopoietic gene expression networks. by Jeffrey L. Kurkewich (3044211)

“…EBF1 and Pax5 were significantly downregulated in ShTrb3 knockdown cells <b>F)</b> Trib3 knockdown in A20 cells resulted in decreased FoxO1 expression by immunoblot analysis. …”

Decrease in egg size and oviposition in <i>S</i>. <i>mansoni</i> females exposed to 20 μM GSK343 for 24 or 48 h. by Adriana S. A. Pereira (5900249)

Total viable immune cells and macrophages decrease acutely while neutrophils and macrophage increase at day 30 in parotid glands after 5Gy IR. by Jordan A. Gunning (18143970)

Cytosolic Ca²⁺ increase in endothelial cells and cytosolic Ca²⁺ decrease in smooth muscle cells induced by CNP. by Fernanda A. Andrade (558039)

Table_2_Antiretroviral Treatment-Induced Decrease in Immune Activation Contributes to Reduced Susceptibility to Tuberculosis in HIV-1/Mtb Co-infected Persons.xlsx by Katalin A. Wilkinson (10193231)

“…Next, we evaluated 30 soluble analytes in QuantiFERON Gold in-tube (QFT) samples from the Ag stimulated and Nil tubes, during the first 6 months of ART in 30 patients. There was a significant decrease in IL-1alpha and IL-1beta (Ag-Nil) concentrations as well as MCP-1 (Nil), supporting decreased immune activation and inflammation. …”

Mean pace of decrease in mortality rates for White (front row) and Black (back row) women for the thirteen U.S. states from 1975 through 2010. by Mohammad A. Tabatabai (630217)

BMP/SMAD and AKT/FoxO1 signaling is critical for mirn23a mediated immune cell regulation. by Jeffrey L. Kurkewich (3044211)

“…Overexpression of MyrAkt1 decreased B cell development and also abrogated the effect of mirn23a loss. …”

Mirn23a regulates critical hematopoietic gene expression networks to influence cell fate decisions. by Jeffrey L. Kurkewich (3044211)

“…Overexpression of miR-23acl or miR-23a alone results in significantly decreased expression of RLU when the Bach1 3’ UTR is present <b>D)</b> RNA was prepared from wildtype and <i>mirn23a</i>^<i>-/-</i> EML cells and analyzed by qRTPCR. …”

A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation by Chaitanya A. Kulkarni (9937661)

“…Delivery of diagnostic and therapeutic cargo directly into mitochondria is a powerful approach to study and treat these diseases. …”

Mirn23a regulates balance of MPP3/MPP4 progenitor populations. by Jeffrey L. Kurkewich (3044211)

“…<b>B)</b> The total MPP population was not significantly changed between wildtype and <i>mirn23a</i>^<i>-/-</i> mice. <b>C)</b> <i>Mirn23a</i>^<i>-/-</i> mice had significantly increased MPP1 and MPP3 populations and significantly decreased MPP2 and MPP4 populations. …”