CCND1 is a target gene of miR-1247-3p. by Dequan Wang (6007007)

Glucose-Driven Droplet Formation in Complexes of a Supramolecular Peptide and Therapeutic Protein by Sihan Yu (11154954)

“…However, the interface can be stabilized by addition of a 4-arm star PEG. When the stabilized droplets formed in glucose are transferred to a bulk phase containing different glucose concentrations, their stability and lifetime decrease according to bulk glucose concentration. …”

Variation of the DC resistivity of Gel/MWCNT nanocomposites as a function of MWCNT content. by Rabeya Binta Alam (17364707)

Subjects:

Copy number variation of <i>FCGR</i> genes in etiopathogenesis of sarcoidosis by Marlena Typiak (4003391)

“…However, this immunocomplexemia might also be caused by decreased clearance by immune cells due to a changed copy number of <i>FCGR</i> genes. …”

Altered splicing of GSK3β by <i>Jmjd6</i>a knockdown augments canonical Wnt/β-catenin signaling in <i>Xenopus laevis</i> development. by Jee Yoon Shin (7067369)

“…(B) Knockdown of <i>Jmjd6a</i> induces decreased phosphorylation of β-catenin and increased stability of β-catenin. …”

Cathepsin L promotes secretory IgA response by participating in antigen presentation pathways during <i>Mycoplasma Hyopneumoniae</i> infection by Ning Zhang (23771)

“…When the cells system were transfected with vector CTSL-GFP or incubated with recombinant CTSL (rCTSL) before they were infected with <i>Mycoplasma hyopneumoniae</i> (<i>M</i>.<i>hp</i>), SIgA significantly increased and Ii chain was degraded into smaller intermediates, while SIgA decreased when CTSL was knockdown or inhibited with E64. …”

Jmjd6a regulates <i>GSK3β</i> RNA splicing in <i>Xenopus laevis</i> eye development by Jee Yoon Shin (7067369)

“…Knockdown of <i>Jmjd6a</i> by an antisense morpholino resulted in eye malformation including a deformed retinal layer and no lens formation. …”

Expression of human Bcl-xL (Ser49) and (Ser62) mutants in <i>Caenorhabditis elegans</i> causes germline defects and aneuploidy by Prasamit Saurav Baruah (3155196)

“…<div><p>An interesting feature of Bcl-xL protein is the presence of an unstructured loop domain between α1 and α2 helices, a domain not essential for its anti-apoptotic function and absent in CED-9 protein. …”

DataSheet_1_Vacuolar Membrane ATPase Activity 21 Predicts a Favorable Outcome and Acts as a Suppressor in Colorectal Cancer.doc by Fan Zhang (46132)

“…VMA21 expression suppresses CRC growth and predicts a favorable DSS in patients with stage I-III disease.…”

Knockdown of <i>Jmjd6a</i> leads to various eye defects in <i>Xenopus laevis</i> development. by Jee Yoon Shin (7067369)

“…<p>(A) Injection of <i>Jmjd6</i> MO results in various eye defects (normal to severe) in the injected side of embryos (red arrows) at stage 40 (n = 3). …”

Pharmacological Inhibition of Monoacylglycerol O-Acyltransferase 2 Improves Hyperlipidemia, Obesity, and Diabetes by Change in Intestinal Fat Utilization by Kazumi Take (200212)

“…CompA decreased high-fat diet (HFD) intake in C57BL/6J mice. …”

Mice Expressing a "Hyper-Sensitive" Form of the Cannabinoid Receptor 1 (CB₁) Are Neither Obese Nor Diabetic by David J. Marcus (2921505)

“…Therefore, the hypothesis that sustained endocannabinoid signaling can lead to obesity and diabetes was examined in this study using S426A/S430A mutant mice expressing a desensitization-resistant CB₁ receptor. …”

DataSheet_1_Transcriptional Profiling and Functional Analysis of N1/N2 Neutrophils Reveal an Immunomodulatory Effect of S100A9-Blockade on the Pro-Inflammatory N1 Subpopulation.doc... by Andreea C. Mihaila (11252988)

“…S100A9 inhibition with a specific small-molecule blocker, reduced CCL2, CCL3 and CCL5 chemokine expression and decreased MPO and MMP-9 activity, by interfering with the NF-kB signaling pathway. …”

Table_1_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.DOCX by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_1_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_4_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_2_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Image_3_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Vascular and Inflammatory High Fat Meal Responses in Young Healthy Men; A Discriminative Role of IL-8 Observed in a Randomized Trial by Diederik Esser (148846)

“…<div><h3>Background</h3><p>High fat meal challenges are known to induce postprandial low-grade inflammation and endothelial dysfunction. This assumption is largely based on studies performed in older populations or in populations with a progressed disease state and an appropriate control meal is often lacking. …”

Inverse relation between I_basal and R_a arises from the decrease in Gα available for GIRK activation at higher I_basal. by Daniel Yakubovich (823436)