Defective cellular signalling in <i>Cdkl5</i> knockout mice. by Elena Amendola (565348)

“…(<b>C</b>) Western blot quantification revealed a significant decrease in phospho-Akt immunoreactivity protein in mutant <i>Cdkl5</i> mice compared with wild-type controls (female: WT, N = 10, HET, N = 6, KO, N = 10; male: WT, N = 5, KO, N = 6; mean ± SEM) (mean ± SEM; *P<0.05, **P<0.01). …”

DataSheet1_Structural features and antioxidant activities of polysaccharides from different parts of Codonopsis pilosula var. modesta (Nannf.) L. T. Shen.ZIP by Li-Xia Li (6517229)

“…The monosaccharide composition of CLRP-1 was Ara, Rha, Fuc, Xyl, Man, Gal, GlcA, GalA in a ratio of 3.8: 8.4: 1.0: 0.8: 2.4: 7.4: 7.5: 2.0: 66.7, and Ara, Rha, Gal, GalA in a ratio of 5.8: 8.9: 8.0: 77.0 in for CLSP-1. …”

Particle-Size-Dependent Distribution of Carboxylate Adsorption Sites on TiO₂ Nanoparticle Surfaces:  Insights into the Surface Modification of Nanostructured TiO<sub>2</... by Qing-Li Zhang (2706889)

“…Size-dependent surface binding forms of the carboxylic group on the surface of TiO₂ nanoparticles were investigated by a surface-binding transient probe molecule all-<i>trans</i>-retinoic acid (ATRA), where the excited triplet-state probe molecule generated by a photoinduced interfacial charge recombination for the adsorbed monolayer acts as a reporter for the different surface binding forms. …”

Table_2_Microbial Community Redundancy and Resilience Underpins High-Rate Anaerobic Treatment of Dairy-Processing Wastewater at Ambient Temperatures.XLSX by Lara M. Paulo (8567841)

“…For example, the main pH shock led to a drop in the methane content to 15%, COD removals decreased to 0%, while the archaeal population decreased to ~11% both at DNA and cDNA levels. …”

Solvation and Thermalization of Electrons Generated by above-the-Gap (12.4 eV) Two-Photon Ionization of Liquid H₂O and D₂O by Rui Lian (2533948)

“…The “continuous blue shift” and the “temperature jump” models, in which the spectral profile does not change as it progressively shifts, as a whole, to the blue, are not supported by our data. …”

siRNA induces transcription initiation arrest, but not DNA methylation or histone deacetylation, of heparanase promoter. by Guosong Jiang (182435)

“…The symbol (#) indicates a significant decrease from untransfected control (mock) or siScb. …”

Data_Sheet_1_Gene Co-expression Network Reveals Potential New Genes Related to Sugarcane Bagasse Degradation in Trichoderma reesei RUT-30.PDF by Gustavo Pagotto Borin (751443)

“…Our results demonstrate a vast range of new promising targets that merit additional studies to improve the cellulolytic potential of T. reesei strains and to decrease the production costs of 2G ethanol.…”

Particle-Size-Dependent Distribution of Carboxylate Adsorption Sites on TiO₂ Nanoparticle Surfaces:  Insights into the Surface Modification of Nanostructured TiO<sub>2</... by Qing-Li Zhang (2706889)

“…Size-dependent surface binding forms of the carboxylic group on the surface of TiO₂ nanoparticles were investigated by a surface-binding transient probe molecule all-<i>trans</i>-retinoic acid (ATRA), where the excited triplet-state probe molecule generated by a photoinduced interfacial charge recombination for the adsorbed monolayer acts as a reporter for the different surface binding forms. …”

Endothelin-1 Inhibits Prolyl Hydroxylase Domain 2 to Activate Hypoxia-Inducible Factor-1α in Melanoma Cells by Francesca Spinella (247034)

“…<div><h3>Background</h3><p>The endothelin B receptor (ET_BR) promotes tumorigenesis and melanoma progression through activation by endothelin (ET)-1, thus representing a promising therapeutic target. The stability of hypoxia-inducible factor (HIF)-1α is essential for melanomagenesis and progression, and is controlled by site-specific hydroxylation carried out by HIF-prolyl hydroxylase domain (PHD) and subsequent proteosomal degradation.…”

HuR silencing destabilizes <i>Cox-2</i> mRNA in CSE-exposed <i>AhR^−/−</i> lung fibroblasts. by Michela Zago (463762)

“…<p>Fibroblasts were transiently transfected with two siRNA against HuR (siRNA-1 and siRNA-2) or control (Ctrl) siRNA, exposed to CSE and <i>Cox-2</i> mRNA stability evaluated by ActD chase experiments. (A) Transfection of <i>AhR^−/−</i> fibroblasts with HuR siRNA significantly reduced HuR protein levels between 50–70%. …”

Juvenile Hormone (JH) regulation of <i>Tc-torso</i> expression in <i>Tribolium</i>. by Sílvia Chafino (17458513)

“…<p>(A) Temporal changes in <i>Tc-torso</i> mRNA levels measured by qRT-PCR in <i>Control</i> and starved animals at the indicated stages. …”

Table_3_Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress.docx by Rongmiao Hou (14507159)

“…<p>Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application. …”

Analysis of 13,312 benthic invertebrate samples from German streams reveals minor deviations in ecological status class between abundance and presence/absence data by Dominik Buchner (8173911)

“…DNA-based tools, such as DNA metabarcoding, provide a new and precise method for species identification but cannot deliver robust abundance data. …”

Characterizing suboptimal child passenger safety practices in crashes with fatalities: Child, driver, vehicle, neighborhood, and policy factors by Arthi S. Kozhumam (14176683)

“…The strongest predictors of suboptimal practices were child age 4-7 years (OR 1.10, 95% CI 1.09-1.12) vs. <4 years and vehicle over capacity (OR 1.09, 95% CI 1.06-1.11). There was a decrease in suboptimal child passenger safety practices with increasing vehicle model year, COI level, fines, and law scores. …”

Image2_Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations.TIFF by Triana Espinosa-Jiménez (12504080)

“…Different techniques, such as GolgiStain kit or immunofluorescence, were used to evaluate the role of PPARβ/δ in memory dysfunction. Our results showed a decrease in dendritic spine density and synaptic markers in PPARβ/δ^-/- mice, which were corroborated in the NORT. …”

Competitive tuning: Competition's role in setting the frequency-dependence of Ca²⁺-dependent proteins by Daniel R. Romano (4574287)

“…Normally, proteins form networks that when activated produce persistent changes in a synapse’s molecular composition. In hippocampal neurons, calcium ion (Ca²⁺) flux through N-methyl-D-aspartate (NMDA) receptors activates Ca²⁺/calmodulin signal transduction networks that either increase or decrease the strength of the neuronal synapse, phenomena known as long-term potentiation (LTP) or long-term depression (LTD), respectively. …”

Table_6_The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.DOCX by Thabatta Leal Silveira Andrezo Rosa (5489132)

“…During thalidomide administration, the drug of choice for ENL treatment, a decrease in the mRNA and protein levels of some of these genes both in the skin and blood was observed. …”

Data_Sheet_1_Initial Experience of Challenge-Free MRI-Based Oxygen Extraction Fraction Mapping of Ischemic Stroke at Various Stages: Comparison With Perfusion and Diffusion Mapping... by Shun Zhang (334141)

“…The OEF value of infarct core showed a trend of decrease from acute, to early subacute, and to late subacute stages of ischemic stroke. …”

Image_1_Immunosuppression Has Long-Lasting Effects on Circulating Follicular Regulatory T Cells in Kidney Transplant Recipients.TIF by Qian Niu (425660)

“…A history of alemtuzumab therapy did lead to a significant decrease in cTfr cells of 85.8% (median) compared with patients not treated with anti-rejection therapy (p < 0.0001). …”

MG-132 enhanced apoptosis induction and caspase-8 cleavage due to DX1 treatment in HL-60 cells. by Zhiying Yu (356965)

“…<p>(<b>A</b>) <b>Western blot analysis of PARP, caspase-8 and c-FLIP levels in HL-60 cells treated with MG-132.…”