Data_Sheet_2_Identification of Quantitative Trait Loci Associated With Iron Deficiency Tolerance in Maize.xlsx by Jianqin Xu (833917)

“…Compared with N1, N2 resulted in a 70.0% decrease of the root Fe concentration for Wu312 in the −Fe treatment, N2 treatment reduced the root Fe concentration of Ye478 by 55.8% in the −Fe treatment. …”

DataSheet1_Modified Baihu decoction therapeutically remodels gut microbiota to inhibit acute gouty arthritis.PDF by Xianyang Wang (2349529)

“…While the relative abundance of Lactobacillaceae, Erysipelotrichaceae, Ruminococcaceae, Prevotellaceae and Enterobacteriaceae showed a relative decrease in species abundance. Of these, the reduction in species abundance of Enterobacteriaceae was associated with a reduction in amino acid metabolism and environmental perception. …”

Prediction of Retention Time and Collision Cross Section (CCS_H+, CCS_H–, and CCS_Na+) of Emerging Contaminants Using Multiple Adaptive Regression Spl... by Alberto Celma (4092583)

“…Multivariate and univariate models were evaluated showing a better fit for univariate models to the experimental data. …”

Table_1_Supplemental Xylooligosaccharide Modulates Intestinal Mucosal Barrier and Cecal Microbiota in Laying Hens Fed Oxidized Fish Oil.DOCX by Jian-min Zhou (10175516)

“…The abundance of Erysipelatoclostridium decreased by XOS addition was negatively associated with ileal VH, VCR, ileal mucosal sIgA content, and the relative expression of zonula occludens-2, CLDN1, and CLDN5. …”

Measurements of Sycp3 vs. by Yana P. Blokhina (6239588)

“…The highest numbers of engaged telomere ends were observed in L and L/EZ stages after which point there was a significant decrease in engaged telomere ends in the EZ/MZ category, p < 0.0001 (unpaired t test with Welch’s correction), however, some number of engaged ends were maintained throughout prophase I. …”

Exploiting Co-Benefits of Increased Rice Production and Reduced Greenhouse Gas Emission through Optimized Crop and Soil Management by Ning An (618997)

“…Advances in nitrogen, water and crop management (Best Management Practices—BMPs) helped closing existing yield gaps and resulted in a substantial reduction in CO₂-equivalent emission of rice farming despite a tradeoff of increase N₂O emission. …”

Epigenetic regulatory genes as putative cancer amplified driver genes. by Ying Chen (9697)

“…(B) <i>BRD4</i> and <i>YEATS4</i> shRNA activity in a panel of cancer cell lines (Project Achilles). shRNA score denotes the log2 based decrease in the representative shRNA compared to pooled shRNA in cancer cell lines after several rounds of proliferation post-shRNA <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0098293#pone.0098293-Cheung1" target="_blank">[11]</a>. …”

Table_4_Long Non-coding RNAs Rian and Miat Mediate Myofibroblast Formation in Kidney Fibrosis.xlsx by Roel Bijkerk (4662769)

“…In order to identify pericyte long non-coding RNAs (lncRNAs) that could serve as a target to decrease myofibroblast formation and counteract the progression of kidney fibrosis we employed two models of experimental kidney injury, one focused on kidney fibrosis (unilateral ureteral obstruction; UUO), and one focused on acute kidney injury that yields kidney fibrosis in the longer term (unilateral ischemia-reperfusion injury; IRI). …”

Optimization of the Malachite-Green ATPase assay for EHD4^ΔN. by Saif Mohd (19251157)

“…<b>B</b> MLG-based ATPase assays for 4 μM EHD4^ΔN, 500 μg/ml DOPS and 50 μM ATP were done at 37°C and 30°C. A further decrease to 25°C did not affect the enzymatic activity compared to 30°C (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0302704#pone.0302704.s002" target="_blank">S2I Fig</a>). …”

Reliable and robust method for abdominal muscle mass quantification using CT/MRI: An explorative study in healthy subjects by Jisuk Park (7405823)

“…In terms of the measurement level, TAMA did not differ from the L2_inf to L4_inf levels, whereas TPA increased with a decrease in measurement level.</p><p>Conclusions</p><p>TAMA is a better biomarker than TPA in terms of inter-scan and inter-reader agreement and robustness to the measurement level. …”

Data_Sheet_3_Generation and Validation of miR-100 Hepatocyte-Specific Knock-Out Mice.PDF by Dong Yang (141041)

“…<p>Background: Inactivation of microRNA-100 (miR-100) is involved in hepatocellular carcinoma (HCC) and miR-100 behaves as a tumor suppressor. To understand miR-100 function in HCC genesis and development in vivo, we developed hepatocyte-specific miR-100 deficient mice.…”

Table_7_The Type I Interferon Pathway Is Upregulated in the Cutaneous Lesions and Blood of Multibacillary Leprosy Patients With Erythema Nodosum Leprosum.DOCX by Thabatta Leal Silveira Andrezo Rosa (5489132)

“…During thalidomide administration, the drug of choice for ENL treatment, a decrease in the mRNA and protein levels of some of these genes both in the skin and blood was observed. …”

Image_2_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The orthostatic challenge test is a standard autonomic function test that measures a decrease of blood pressure during a postural change from supine to standing positions. …”

Image_1_Resting Heart Rate Variability Is Associated With Subsequent Orthostatic Hypotension: Comparison Between Healthy Older People and Patients With Rapid Eye Movement Sleep Beh... by Yukiyoshi Sumi (5290874)

“…The orthostatic challenge test is a standard autonomic function test that measures a decrease of blood pressure during a postural change from supine to standing positions. …”

Long-range chromatin interactions of κ regulatory elements correlate with V_κ gene usage. by Ralph Stadhouders (523996)

“…<p>(A) Selected examples of genomic regions containing V_κ⁺ fragments, showing increased (V_κ4–57, V_κ6–25, V_κ8–24, V_κ4–79), stable (V_κ8–23–1, V_κ4–78, V_κ13–84), or decreased (V_κ3–9, V_κ14–111) 3C-seq interaction frequencies with 3′Eκ or iEκ upon pre-BCR signaling. …”

DataSheet1_Lysosomal TRPML1 triggers global Ca2+ signals and nitric oxide release in human cerebrovascular endothelial cells.docx by Valentina Brunetti (18861187)

“…Notably, interfering with TRPML1-mediated lysosomal Ca²⁺ mobilization led to a decrease in the free ER Ca²⁺ concentration. …”

DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP by Huadong Ke (19937268)

“…The analysis revealed that the ten most frequently reported AEs included bone marrow suppression, myalgia, leukopenia, thrombocytopenia, nausea, vomiting, death, rhabdomyolysis, disease progression, and a decrease in neutrophil count. The five most common categories of AEs related to anti-glioma drugs were blood and lymphatic system diseases (20,233 cases, 15.2%), general disorders and administration site conditions (26,973 cases, 20.3%), gastrointestinal dysfunction (22,061 cases, 16.7%), necessitating further investigations (18,285 cases, 13.8%), and musculoskeletal and connective tissue diseases (30,695 cases, 23.1%). …”

Image_3_Microbial Community Redundancy and Resilience Underpins High-Rate Anaerobic Treatment of Dairy-Processing Wastewater at Ambient Temperatures.TIF by Lara M. Paulo (8567841)

“…For example, the main pH shock led to a drop in the methane content to 15%, COD removals decreased to 0%, while the archaeal population decreased to ~11% both at DNA and cDNA levels. …”

Image_2_Genes related to osmoregulation and antioxidation play important roles in the response of Trollius chinensis seedlings to saline-alkali stress.jpg by Rongmiao Hou (14507159)

“…<p>Saline-alkali stress is one of the main abiotic stress factors affecting plant growth and development. Trollius chinensis is a perennial herbal medicinal plant with high values for garden application. …”

Conditional knockout of <i>Ezh2</i> gene in murine hearts caused perinatal lethality. by Li Chen (5749)

“…Semi-quantitative RT-PCR with two different numbers of amplification cycles (30 and 35) was performed on RNA samples purified from WT hearts of E9.5, E10.5, and E11.5. 1 µl or 0.5 µl cDNA from reverse transcription reaction was used for detection of Ezh2 or GAPDH (as a control), respectively. (<b>C</b>) qRT-PCR analysis revealed ∼70% decrease in <i>Ezh2</i> mRNA of <i>Ezh2</i>-cKO heart (n = 3, p<0.001), but <i>Ezh1</i> mRNA was not affected, compared with that of the control littermate hearts. …”