Stabilization of p27^Kip1 through S140 phosphorylation is required for tumorsphere resistance to IR. by Erica K. Cassimere (3111996)

“…Differences between groups were evaluated using two-tailed Student <i>t</i> tests among replicate experiments; **P = 0.005. (E) p27S140A has a decreased half-life compared to p27WT in tumorspheres subjected to IR. …”

Cleavage of osmosensitive transcriptional factor NFAT5 by Coxsackieviral protease 2A promotes viral replication by Ye Qiu (363315)

“…In this study, we aimed to understand the mechanism by which NFAT5 interferes with infection of Coxsackievirus B3 (CVB3), a major cause of viral myocarditis. Our initial results demonstrated that although the mRNA level of NFAT5 remained constant during CVB3 infection, NFAT5 protein level decreased because the protein was cleaved. …”

Functional regulatory mechanism of smooth muscle cell-restricted <i>LMOD1</i> coronary artery disease locus by Vivek Nanda (746334)

“…<i>LMOD1</i> knockdown results in increased proliferation and migration and decreased cell contraction in HCASMC, and immunostaining in atherosclerotic lesions in the SMC lineage tracing reporter mouse support a key role for LMOD1 in maintaining the differentiated SMC phenotype. …”

mGluR1 facilitates anchorage-independent growth. by Malathi Banda (505556)

“…<p><b>A and B. MCF10AT1 cells.</b> Cells were transduced with either with pLenti-<i>GRM1</i>, pLenti-<i>LacZ</i>, sh<i>GRM1</i>, or NS control vector and stably selected before plating in soft agar. …”

<i>Mycobacterium tuberculosis</i>-induced miR-155 subverts autophagy by targeting ATG3 in human dendritic cells by Marilena P. Etna (4735113)

“…Late in infection, when miR-155 expression peaked, both the level of Atg3 and the number of LC3 puncta per cell (autophagosomes) decreased dramatically. In accordance, miR-155 silencing rescued autophagosome number in Mtb infected DC and enhanced autolysosome fusion, thereby supporting a previously unidentified role of the miR-155 as inhibitor of ATG3 expression. …”

Mutations in Mtr4 Structural Domains Reveal Their Important Role in Regulating tRNA_i^Met Turnover in <i>Saccharomyces cerevisiae</i> and Mtr4p Enzymatic Activi... by Yan Li (23143)

“…<div><p>RNA processing and turnover play important roles in the maturation, metabolism and quality control of a large variety of RNAs thereby contributing to gene expression and cellular health. …”

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations by Harsh Sheth (4843305)

“…Meta-analysis of SNPs rs2070959 and rs1105879 in <i>UGT1A6</i> gene showed interaction between aspirin use and CRC risk (<i>P</i>_interaction = 0.01 and 0.02, respectively); stratification by aspirin use showed an association for decreased CRC risk for aspirin users having a wild-type genotype (rs2070959 OR = 0.77, 95% CI = 0.68–0.86; rs1105879 OR = 0.77 95% CI = 0.69–0.86) compared to variant allele cariers. …”

Inhibition of cAMP-Dependent PKA Activates β₂-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A₂ via Raf-1/MEK/ERK and IP₃-Dependent Ca<... by M. R. Pabbidi (3560993)

“…<div><p>We previously reported in atrial myocytes that inhibition of cAMP-dependent protein kinase (PKA) by laminin (LMN)-integrin signaling activates β₂-adrenergic receptor (β₂-AR) stimulation of cytosolic phospholipase A₂ (cPLA₂). The present study sought to determine the signaling mechanisms by which inhibition of PKA activates β₂-AR stimulation of cPLA₂. …”

In vivo performance of FRCaMPi and SomaFRCaMPi in neurons in zebrafish larvae. by Shihao Zhou (5774795)

“…<b>(B)</b> Representative single plane confocal images of periventricular cell bodies in optic tectum of fish expressing jRGECO1a, FRCaMPi or SomaFRCaMPi. Decreased neuropil fluorescence and clearer neuronal cell bodies was found in SomaFRCaMPi-expressing larval zebrafish. …”

Accelerated weathering effects on poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and PHBV/TiO2 nanocomposites by Antunes, A.

“…It also slowed down the decrease in mechanical properties. The mechanical properties were shown to gradually decrease for the PHBV/TiO2 nanocomposites, whereas a sharp drop was observed for the neat PHBV after an accelerated weathering exposure. …”
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A reliable and cost-effective planning framework of rural area hybrid system considering intelligent weather forecasting by Abazari, A.

“…Moreover, the growth of fuel cost causes an increase in the production of renewable energy resources (RESs) and a decrease in the usage of diesel engine generators. …”
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Data_Sheet_1_Life Cycle Dynamics of a Key Marine Species Under Multiple Stressors.PDF by Saskia A. Otto (6717152)

“…As a consequence, we found that a favorable increase of oxygen and phosphate conditions together with a reduction in predation pressure by 50% each could counteract the negative effect of a 25% decrease in salinity by only 6%. …”

Molecular and Functional Profiling of the Polyamine Content in Enteroinvasive <i>E. coli</i> : Looking into the Gap between Commensal <i>E. coli</i> and Harmful <i>Shigella</i> by Rosaria Campilongo (626526)

“…<div><p>Polyamines are small molecules associated with a wide variety of physiological functions. Bacterial pathogens have developed subtle strategies to exploit polyamines or manipulate polyamine-related processes to optimize fitness within the host. …”

Visual Detection of Speckles in the Fish <i>Xenotoca variata</i> by the Predatory Snake <i>Thamnophis melanogaster</i> in Water of Different Turbidity by Javier Manjarrez (531011)

“…We predicted that in an experimental laboratory test, the snakes would increase the frequency of their predatory behavior to the extent that the water turbidity decreases. The snakes were tested at six different levels of water turbidity, in combination with three categories of male fish (with few, a median number of, or many speckles). …”

Video-Assisted Thoracoscopic Lobectomy for Giant Congenital Bulla of the Left Upper Lobe: A Case Report by Vu Than Trong (7288058)

“…<p>A 17-year-old woman was admitted to the authors’ hospital with left chest pain, cough, and dyspnea. …”

Cadaverine interferes with <i>speC</i> expression. by Rosaria Campilongo (626526)

The <i>Airn</i> CGI plays a major role in <i>Airn</i> transcription and function. by Martha V. Koerner (180097)

“…(D) ChIP for Ser5P/Ser2P RNAPII in <i>S12/+</i>, <i>S12/TDRΔ</i>-1A and <i>S12/CGIΔ</i>-1A d11 cells shows unaffected <i>Airn</i> initiation and elongation (except at <i>Airn</i>-end) in <i>TDRΔ</i> and a sharp RNAPII decrease in the <i>CGIΔ</i> allele. …”

Chronological changes in the pattern of sessile cells in <i>Drosophila</i> larvae after a wasp infection. by Ines Anderl (611071)

“…Secondary lymph gland lobes were hypertrophied (B”‘-B”“, C”‘-C”“), whereas primary lymph gland lobes were always absent (B”“‘, C”“‘). A <i>L</i>. <i>heterotoma</i> infection led to a decrease in sessile blood cell numbers. …”

Molecular and functional analysis of the <i>ynfB-speG</i> operon in EIEC. by Rosaria Campilongo (626526)

Disentangling the influence of environmental and anthropogenic factors on the distribution of endemic vascular plants in Sardinia by Mauro Fois (568645)

“…<div><p>Due to the impelling urgency of plant conservation and the increasing availability of high resolution spatially interpolated (e.g. climate variables) and categorical data (e.g. land cover and vegetation type), many recent studies have examined relationships among plant species distributions and a diversified set of explanatory factors; nevertheless, global and regional patterns of endemic plant richness remain in many cases unexplained. …”