<b>Type 1 diabetes depends on CD4-driven expression of the transcriptional repressor, </b><b><i>Bcl6</i></b> by Dudley H. McNitt (20208081)

“…These data highlight BCL6 as a novel therapeutic target in type 1 diabetes.</p>…”

Table1_Mid-Late Holocene Sub-Millennial Scale Inverse Trends of South Asian Summer and Winter Monsoons in Sri Lanka.docx by Kasun Gayantha (11834375)

“…Multiple proxies (diagnostic biomarkers, hydrogen and carbon isotopes of individual n-alkane, grain size, and Zr/Rb elemental ratio) indicate a sub-millennial scale decreasing trend of summer monsoon rainfall in the wet zone of Sri Lanka alongside an increasing trend of winter monsoon rainfall in the dry zone during the last ∼6000 years. …”

Image_1_Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasi... by M-K. Torp (12332864)

Table_1_Modulation of Fermentation Quality and Metabolome in Co-ensiling of Sesbania cannabina and Sweet Sorghum by Lactic Acid Bacterial Inoculants.docx by Tianqi Xia (5558435)

“…<p>Sesbania cannabina (SC) is a protein-rich roughage that thrives under moderate-severe saline-alkali (MSSA) soils with the potential to relieve the shortage of high nutritive forage. …”

DataSheet1_Cardioprotective and hypotensive mechanistic insights of hydroethanolic extract of Cucumis melo L. kernels in isoprenaline-induced cardiotoxicity based on metabolomics a... by Muqeet Wahid (17862647)

“…<p>Background: Cardiovascular diseases (CVD) continue to threaten health worldwide, and account for a significant portion of deaths and illnesses. …”

Table_1_Echocardiographic Prediction of Left Ventricular Dysfunction After Transcatheter Patent Ductus Arteriosus Closure in Children.DOCX by Miao Hou (340226)

“…</p><p>Conclusion: Transcatheter closure of PDA causes a significant deterioration in LV systolic function early after PDA closure, which recovered completely within 3 months of post-closure in children. …”

Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration by Victoria Begley (4670281)

“…According to these and other pieces of evidence, Xrn1 seems to influence transcription elongation at least in two ways: by directly favouring elongation rates and by a more general mechanism that connects mRNA decay to late elongation.…”

Table 1_Clinical characteristics and immunotherapy response in paraneoplastic neurologic syndrome patients with increased number of high-risk antibodies.docx by Gong Wang (745924)

“…</p>Conclusions<p>Psychobehavioral abnormality, bowel and bladder dysfunction, and total protein of CSF were three variables associated with increased number of high-risk antibodies in PNS patients, while increased number of high-risk antibodies might indicate a poor immunotherapy response. Our findings might help to understand the association of PNS patients’ clinical features and high-risk antibodies, as well as to guide clinical practice.…”

Image_1_Porcine epidemic diarrhea virus strain FJzz1 infection induces type I/III IFNs production through RLRs and TLRs-mediated signaling.tiff by Pengfei Chen (462170)

“…In this study, we observed that various IFN-stimulated genes (ISGs) were upregulated significantly in a time- and dose-dependent manner in LLC-PK1 cells infected with the PEDV G2 strain FJzz1. …”

Gene Profile of Chemokines on Hepatic Stellate Cells of Schistosome-Infected Mice and Antifibrotic Roles of CXCL9/10 on Liver Non-Parenchymal Cells by Yue-jin Liang (144722)

“…<div><p>Hepatic stellate cells (HSCs) play a key role in the development of liver fibrosis caused by schistosomiasis. …”

Image_1_Change of mortality of patients with acute ischemic stroke before and after 2015.TIF by Sang-Won Park (180226)

“…</p>Materials and methods<p>A retrospective cohort study was conducted using combined anonymized data from the Acute Stroke Assessment Registry of Korea and the Health Insurance Review & Assessment Service database. …”

Image1_Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.TIFF by Haomiao Li (2743693)

“…</p><p>Discussion: Our findings support a universal role of insect Ilp8 in female fecundity, and also provide novel clues for understanding the modes of action of Ilp8.…”

Image_2_EP3 Blockade Adds to the Effect of TP Deficiency in Alleviating Endothelial Dysfunction in Atherosclerotic Mouse Aortas.JPEG by Chuangjia Hu (7433447)

“…EP3 antagonism not only increased the above relaxation, but also reversed the contractile response evoked by acetylcholine in NO synthase-inhibited atherosclerotic ApoE^–/–/TP^–/– rings into a relaxation sensitive to I prostanoid receptor antagonism. …”

Data file. by Md. Utba Rashid (10700694)

“…The average physical domain score decreased significantly from baseline to follow-up, whereas a significant increase in average scores has been observed in other domains at the follow-up (p<0.05). …”

DataSheet4_Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway.ZIP by Xiaowan Wang (9704207)

“…To investigate the effects of SQ, we established the experimental passive Heymann nephritis (PHN) rat model induced by anti-Fx1A antiserum in vivo and doxorubicin hydrochloride (ADR)-injured apoptotic podocyte model in vitro. …”

Table1_Oxidative balance score reflects vascular endothelial function of Chinese community dwellers.DOCX by Jianhua Liu (33232)

“…<p>Background: The oxidative balance score (OBS) is a composite estimate of the overall pro- and antioxidant risk status in an individual. …”

Image1_Krill Oil Alleviated Methamphetamine-Induced Memory Impairment via the MAPK Signaling Pathway and Dopaminergic Synapse Pathway.tif by Qin Ru (11623021)

“…The combination of network pharmacology approaches with experimental validation may offer a useful tool to characterize the molecular mechanism of multicomponent complexes.…”

Data Sheet 1_Longitudinal analysis of usage and public awareness of tyrosine kinase inhibitors for CML.docx by Adrian E. Schroer (17937971)

“…</p>Discussion<p>These data highlight a shift toward newer TKIs in CML treatment, mirroring guideline recommendations and rising public awareness. …”

Table_1_Wheat F-box Protein TaFBA1 Positively Regulates Plant Drought Tolerance but Negatively Regulates Stomatal Closure.doc by Jie An (543888)

“…In addition, TaFBA1 was found to be a negative regulator of ABA-induced stoma movement; mRNA transcription of certain ABA signaling-related genes was lower in TaFBA1 OE plants than in WT plants following ABA treatment. …”

DataSheet1_Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice.docx by Lu Xia (1509745)

“…</p><p>Conclusion: GSDMD-mediated pyroptosis is involved in the mechanism of kainic acid-induced seizures. Our study provides a new potential therapeutic target for seizure control.…”