Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Representative band diagrams of states, in our 2D and in 3D studies, illustrating transitions between different spiral-wave (for 2D) and scroll-wave (for 3D) states as a function o... by Rupamanjari Majumder (128411)

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Themes and subthemes used for rapid qualitative analysis. by Olufunto A. Olusanya (14142040)

Video_1_The Combined Efficacy of a Two-Year Period of Cybernic Treatment With a Wearable Cyborg Hybrid-Assistive Limb and Leuprorelin Therapy in a Patient With Spinal and Bulbar Mu... by Hideaki Nakatsuji (445319)

“…<p>Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a rare, slowly progressive, incurable, and hereditary neurodegenerative disease caused by the testosterone-dependent accumulation of pathogenic polyglutamine-expanded androgen receptor protein. …”

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate:  A Coverage-Dependent Study by Caroline M. Whelan (2529898)

“…A decrease in film order and the absence of a preferred molecular orientation is observed for all three molecules at multilayer coverages. …”

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate:  A Coverage-Dependent Study by Caroline M. Whelan (2529898)

“…A decrease in film order and the absence of a preferred molecular orientation is observed for all three molecules at multilayer coverages. …”

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate:  A Coverage-Dependent Study by Caroline M. Whelan (2529898)

“…A decrease in film order and the absence of a preferred molecular orientation is observed for all three molecules at multilayer coverages. …”

VEGF, MMP-2, and MMP-9 expression after treatment of t-BH on ARPE-19 cells and HUVECs. by Eun Kyoung Lee (644077)

“…<p>Expression of mRNAs for vascular endothelial growth factor (VEGF), matrix metalloproteinase (MMP)-2, and MMP-9 determined by real-time quantitative polymerase chain reaction (PCR) were evaluated in human retinal pigment epithelial (ARPE-19) cells (A, C, E) and in human umbilical vein endothelial cells (HUVECs) (B, D, F). …”

Response of the Myc-Rb-E2F network to pulse inputs. by Jaydeep K. Srimani (618692)

“…<p>(A) In response to serum stimulation, the Myc-Rb-E2F can exhibit bistability in E2F levels. …”

Fig 1 - by Yuh-Chin T. Huang (17867207)

Expression of Linear and Novel Circular Forms of an <em>INK4/ARF</em>-Associated Non-Coding RNA Correlates with Atherosclerosis Risk by Christin E. Burd (236068)

“…<div><p>Human genome-wide association studies have linked single nucleotide polymorphisms (SNPs) on chromosome 9p21.3 near the <em>INK4/ARF (CDKN2a/b)</em> locus with susceptibility to atherosclerotic vascular disease (ASVD). …”

Aspirin treatment does not increase microhemorrhage size in young or aged mice by Sandy Chan (3758512)

“…There remains a concern that such aspirin usage may prolong bleeding after a vessel rupture in the brain, leading to larger bleeds that cause more damage to the surrounding tissue. …”

Weak links and k-cores pre-quarantine. by Matteo Serafino (11599593)

A Mouse Model for Studying the Clearance of Hepatitis B Virus In Vivo Using a Luciferase Reporter by Sheng-qiang Liang (359591)

“…In vivo direct evaluation of anti-HBV immunity in the liver is currently not possible. We have developed a new assay system that detects HBV clearance in the liver after the hydrodynamic transfer of a reporter gene and over-length, linear HBV DNA into hepatocytes, followed by bioluminescence imaging of the reporter gene (Fluc). …”

Effect of trauma on asylum seekers and refugees receiving a WHO psychological intervention: a mediation model by Riccardo Serra (11642588)

“…</p> <p></p><p>Increasing numbers of potentially traumatic experiences can decrease the beneficial effect of a manualized group psychotherapeutic intervention in migrants and refugees across multiple countries.…”

Keyword recovery scores as a function of combined intergenic distances between pairs of genes in a run by Michael Strong (2076)

“…While the keyword recovery of genes linked by a combined intergenic distance less than 150 bp is fairly high (34-52%), it is apparent that as the total intergenic distance increases above 150 bp, there is a decrease in keyword recovery. …”