Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Representative band diagrams of states, in our 2D and in 3D studies, illustrating transitions between different spiral-wave (for 2D) and scroll-wave (for 3D) states as a function o... by Rupamanjari Majumder (128411)

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

A Systems Biology Approach Identifies a Regulatory Network in Parotid Acinar Cell Terminal Differentiation by Melissa A. Metzler (732761)

“…The network suggests a molecular switch (involving <i>Prdm1</i>, <i>Sox11</i>, <i>Pax5</i>, miR-200a, and miR-30a) progressively decreases repression of <i>Xbp1</i> gene transcription, in concert with decreased translational repression by miR-214. …”

Cell blebs and cytoskeleton under different DMSO concentrations. by Renquan Ruan (721497)

PhoU is required for MBR in the <i>E</i>. <i>coli</i> chromosome. by Janet L. Gibson (736950)

Forest plot of treatment effects of isoleucine–proline–proline/valine–proline–proline on systolic blood pressure in the subgroup analysis according to the baseline blood pressure s... by Aurelie Chanson-Rolle (758940)

Weak links and k-cores pre-quarantine. by Matteo Serafino (11599593)

Response of the Myc-Rb-E2F network to pulse inputs. by Jaydeep K. Srimani (618692)

“…<p>(A) In response to serum stimulation, the Myc-Rb-E2F can exhibit bistability in E2F levels. …”

Video_1_The Combined Efficacy of a Two-Year Period of Cybernic Treatment With a Wearable Cyborg Hybrid-Assistive Limb and Leuprorelin Therapy in a Patient With Spinal and Bulbar Mu... by Hideaki Nakatsuji (445319)

“…<p>Spinal and bulbar muscular atrophy (SBMA), also known as Kennedy's disease, is a rare, slowly progressive, incurable, and hereditary neurodegenerative disease caused by the testosterone-dependent accumulation of pathogenic polyglutamine-expanded androgen receptor protein. …”

Expression of Linear and Novel Circular Forms of an <em>INK4/ARF</em>-Associated Non-Coding RNA Correlates with Atherosclerosis Risk by Christin E. Burd (236068)

“…<div><p>Human genome-wide association studies have linked single nucleotide polymorphisms (SNPs) on chromosome 9p21.3 near the <em>INK4/ARF (CDKN2a/b)</em> locus with susceptibility to atherosclerotic vascular disease (ASVD). …”

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate:  A Coverage-Dependent Study by Caroline M. Whelan (2529898)

“…A decrease in film order and the absence of a preferred molecular orientation is observed for all three molecules at multilayer coverages. …”

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate:  A Coverage-Dependent Study by Caroline M. Whelan (2529898)

“…A decrease in film order and the absence of a preferred molecular orientation is observed for all three molecules at multilayer coverages. …”

Adsorption of Fumaramide [2]Rotaxane and Its Components on a Solid Substrate:  A Coverage-Dependent Study by Caroline M. Whelan (2529898)

“…A decrease in film order and the absence of a preferred molecular orientation is observed for all three molecules at multilayer coverages. …”

Model of regulation of the Pho regulon. by Janet L. Gibson (736950)

Biometric evaluation and nutrients of the corn, pearl millet, and sorghum crops by Paulo Henrique Borgati Chrisostomo (13891471)

“…For the characterization of nutrient accumulation and biometric evaluation, linear and nonlinear models were used. Dry matter accumulation did not differ between corn and sorghum, but decreased in pearl millet from the fiftieth day up to ensiling. …”

A Mouse Model for Studying the Clearance of Hepatitis B Virus In Vivo Using a Luciferase Reporter by Sheng-qiang Liang (359591)

“…In vivo direct evaluation of anti-HBV immunity in the liver is currently not possible. We have developed a new assay system that detects HBV clearance in the liver after the hydrodynamic transfer of a reporter gene and over-length, linear HBV DNA into hepatocytes, followed by bioluminescence imaging of the reporter gene (Fluc). …”

Flow diagram of study selection. by Aurelie Chanson-Rolle (758940)

Effect of trauma on asylum seekers and refugees receiving a WHO psychological intervention: a mediation model by Riccardo Serra (11642588)

“…</p> <p></p><p>Increasing numbers of potentially traumatic experiences can decrease the beneficial effect of a manualized group psychotherapeutic intervention in migrants and refugees across multiple countries.…”

Funnel plot used to explore the potential for publication bias in the meta-analysis of 33 series for the effect of isoleucine–proline–proline/valine–proline–proline on systolic blo... by Aurelie Chanson-Rolle (758940)