The effects of diet and streptozotocin on metabolism and gut microbiota in a type 2 diabetes mellitus mouse model by Ruiyang Yin (4411330)

“…<p>Diabetes mellitus is a metabolic disorder disease. Diabetes models can be established using diet and/or chemical agents. …”

Dopamine signals are coupled to the activation of Akt and inactivation of GSK3β in hippocampal neurons (A–D). by Sigeng Chen (248428)

“…<p>A. Western blot analysis shows that treatment with dopamine (30 nM) for 60 minutes leads to the inactivation of Akt (i.e., decreased serine-473 phosphorylation) and the activation of GSK3β (i.e., decreased serine-9 phosphorylation). …”

Role of a hairpin-stabilized pause in the <i>Escherichia coli thiC</i> riboswitch function by Adrien Chauvier (6693389)

“…Destabilization of this structure led to a weaker pause and a decreased NusA effect. In the context of the full-length riboswitch, this same mutation also led to a weaker pause, as well as a decreased TPP binding affinity. …”

Table_1_Dedicated comparatives aid comparisons of magnitude: a study with Pitjantjatjara-English bilinguals.XLSX by Luke Greenacre (7199756)

“…<p>When expressing comparisons of magnitude, Pitjantjatjara, a language indigenous to the land now known as Australia, employs contextually driven comparators (e.g., Anyupa is tall. …”

Influence of the contact time on the adhesion force of a single <i>Paracoccus seriniphilus</i> cell on glass. by Linda Hofherr (9088766)

“…On the right a zoom of the contact times up to 20 s is shown.…”

Bias in Experiment 1 (top panel) and Experiment 5 (bottom panel) as a function of semantic distance. by Patrizia Turriziani (369138)

Integrin survival signaling is down-regulated in RGC in the retina 1 day after ischemic injury. A. by Andrea Rachelle C. Santos (300999)

“…</b> β1 integrin expression is decreased in RGC 1 day post-RIRI. Immunohistochemistry with β1 integrin antibodies (red) in frozen retinal sections from control (<b>a, b, c</b>), and ischemic retinas (<b>d, e, f</b>), in which RGCs were retrogradely labeled with FG (green; <b>a, d</b>) shows reduced β1 integrin expression in ischemic eyes in comparison with control eyes (red; <b>b, e</b>) specifically in RGC (yellow; merged; <b>c, f</b>). …”

A Retrospective Survey of Research Design and Statistical Analyses in Selected Chinese Medical Journals in 1998 and 2008 by Zhichao Jin (248636)

“…</p><h3>Methodology/Principal Findings</h3><p>Ten (10) leading Chinese medical journals were selected and all original articles published in 1998 (N = 1,335) and 2008 (N = 1,578) were thoroughly categorized and reviewed. A well-defined and validated checklist on study design, statistical analyses, results presentation, and interpretation was used for review and evaluation. …”

A new family of boost active neutral point clamped inverter topology with reduced switch count by Siddique, Marif Daula

“…The traditional ANPC gives the output voltage of half the input voltage which necessitates the use of higher input dc-link voltage. To fix this problem, a floating capacitor is used to increase the voltage of the output, which decreases the dc-link requirement. …”
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Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis by María José Sánchez-Barrena (109080)

“…Pull-down experiments and immunoprecipitations showed that Bin2 C-terminus bound SH3 domain containing proteins such as Endophilin A2 and α-PIX. siRNA of endogenous protein led to decreased cell migration, increased phagocytosis and reduced podosome density and dynamics. …”

Inhibition of CD23-mediated activation of iNOS pathway in human macrophages by p30A. by Jérôme Rambert (46851)

“…<p>Human CD23⁺ monocyte-derived macrophages were incubated with cross-linking CD23-McAb (20 µg/ml) alone or following 1 h pre-incubation with 10 µg/ml of various peptides. (A) Inducible NO-synthase expression promoted by CD23-mediated activation is decreased in cells pre-incubated with p30A. …”

ARCN stimulation: tracing showing effect of GABA-A, NPY1 and opioid receptor blockade in the PVN. by Tetsuya Kawabe (292023)

“…B: Unilateral microinjection of NMDA (10 mM, 20 nl) into the ARCN elicited decreases in MAP and GSNA and an increase in HR. C: 20 min later, ipsilateral PVN site was identified by a microinjection of NMDA (10 mM, 30 nl); increases in MAP, HR and GSNA were elicited. …”

Phenotype characterization of E12.5 <i>Lmx1a-dr/dr</i> mice. by Elisa J. Hoekstra (290576)

“…(F–J′) <i>Th</i> transcript is rostral-laterally decreased (arrowheads), but also medially. (K–O′) <i>Pitx3</i> and (P–T′) <i>En1</i> display a subtle decreased expression in <i>Lmx1a-dr/dr</i> tissue. …”

Logistic regression plot of the probability of a contestant splitting depending upon the value of the prize fund (Stakes). by Maxwell N. Burton-Chellew (327480)

“…<p>The probability of a contestant splitting decreased with larger stakes. …”

Top networks generated by IPA associated with genes selectively downexpressed by the exposure to the Aβ-Al complex. by Valentina Gatta (139984)

“…<p>Genes in green show decreased expression in SH-SY5Y cells exposed to Aβ-Al when compared with untreated SY5Y cells. …”

The BM vibration measured from a longitudinal location ∼2.5 mm from the cochlear base. by Wenxuan He (328284)

“…Panels A and C show high sensitivity, sharp tuning, and nonlinear compression while panels B and D show that the phase decreases with frequency at an accelerated rate, indicating cochlear dispersion.…”

Influence of facial movements on quality of iPPG signal from Sessions 3 (A) and 5 (B). by Anton M. Unakafov (5706560)

Image_1_TUSK: a ubiquitin hydrolase complex modulating surface protein abundance in trypanosomes.jpeg by Kayo Yamada (407407)

“…Silencing SkpZ decreases TbUsp7 and TbTpr86 abundance, confirming a direct association. …”

Smooth Muscle Insulin Receptor Deletion Causes Voiding Dysfunction: A Mechanism for Diabetic Bladder Dysfunction by Huan Chen (6545)

“…In summary, disruption of IR-mediated signaling in BSM caused abnormalities in proliferation and differentiation, leading to diminished BSM contractility and a voiding dysfunction phenotype that recapitulates human DBD. …”

Image_3_TUSK: a ubiquitin hydrolase complex modulating surface protein abundance in trypanosomes.jpeg by Kayo Yamada (407407)

“…Silencing SkpZ decreases TbUsp7 and TbTpr86 abundance, confirming a direct association. …”