A potential role for reduced <i>SOSTDC1</i> expression levels in HD onset modification. by Michael J. Chao (374678)

“…The Y- and X-axes represent significances in GTEx eQTL and modification in our GWA analysis, respectively. Panel A shows SNPs whose minor alleles are associated with decreased expression levels of <i>SOSTDC1</i>. …”

Immunofluorescence staining of E-cadherin and a-SMA protein and analysis of apoptosis in NRK-52E cells. by Lining Jia (2217367)

“…<p>(A) The expression of E-cadherin was increased, and the expression of a-SMA was decreased in the sorafenib-treated group relative to the TGF-β1-stimulated group (<i>p</i><0.05). …”

FGF2 beads produce a more undifferentiated, mouse and human neural stem cell culture. by Steven Lotz (378367)

“…<p>(A) Mouse NSCs grown for one week in FGF2beads show increased progenitor cells (Nestin+) and decreased neuronal differentiation (TUJ1+) compared to no FGF2 and soluble FGF2, data quantified in (B). …”

A potential kidney-heart interplay which may mediate changes in mitochondrial structure and function in CKD. by Einat Bigelman (5367932)

“…<p><b>(A)</b> CKD setting results in cardiac gross pathology (manifested by increased fibrosis, LV mass and cellular hypertrophy) as well as mitochondrial abnormality (manifested by mitochondrial swelling, decreased mitochondrial content and active mitochondrial content) through mild elevation in blood pressure and activation of neurohumoral and immune systems. …”

VACV infection induces non-canonical STAT3 phosphorylation at S727 in a VGF-dependent manner. by Anil Pant (10074299)

“…Protein levels were detected by performing a Western blotting analysis at 4 hpi. <b>(D)</b> Inhibition of the EGFR pathway decreases STAT3 S727 phosphorylation in VACV infected cells. …”

A hypomorphic mutation in <i>Rere</i> is responsible for microphthalmia in <i>eyes3</i> mice. by Bum Jun Kim (381759)

“…<p>A) <i>eyes3</i> mice were identified in an ENU screen for recessive mutations based on microphthalmia and were also found to have decreased body size and occasional unilateral renal agenesis. …”

Inferring Cetacean Population Densities from the Absolute Dynamic Topography of the Ocean in a Hierarchical Bayesian Framework by Mario A. Pardo (704553)

“…<div><p>We inferred the population densities of blue whales (<i>Balaenoptera musculus</i>) and short-beaked common dolphins (<i>Delphinus delphis</i>) in the Northeast Pacific Ocean as functions of the water-column’s physical structure by implementing hierarchical models in a Bayesian framework. This approach allowed us to propagate the uncertainty of the field observations into the inference of species-habitat relationships and to generate spatially explicit population density predictions with reduced effects of sampling heterogeneity. …”

Data Sheet 1_Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study.zip by Argul Issilbayeva (21398168)

“…</p>Conclusion<p>Our findings demonstrate that polyphenol supplementation maintains stable TMAO levels by restructuring gut microbiome composition in STEMI patients, evidenced by a more focused microbiome with a significant increase in beneficial butyrate-producing bacteria (Roseburia, Agathobaculum sp., Alistipes finegoldii, and Sellimonas) and a decreased Firmicutes/Bacteroidetes ratio, suggesting microbiome-mediated cardioprotective effects. …”

Image_1_Oxidative Stress Marker Aberrations in Multiple Sclerosis: A Meta-Analysis Study.pdf by Shu-Yao Zhang (4871887)

“…<p>Oxidative stress has been suggested to play a key role in multiple sclerosis (MS), but clinical data on oxidative stress markers in MS patients were inconsistent. …”

Data Sheet 1_Brucellosis-associated hemophagocytic lymphohistiocytosis: a case report and literature review.docx by Shuwen Jiang (6730370)

“…Introduction<p>Hemophagocytic lymphohistiocytosis (HLH), a rare and deadly disease, is typically classified as either primary (familial) or secondary (acquired), depending on the etiology and underlying cause. …”

Table_1_Oxidative Stress Marker Aberrations in Multiple Sclerosis: A Meta-Analysis Study.pdf by Shu-Yao Zhang (4871887)

“…<p>Oxidative stress has been suggested to play a key role in multiple sclerosis (MS), but clinical data on oxidative stress markers in MS patients were inconsistent. …”

Supplementary Material for: Opioid and Other Medication Use and General Health Status in a Cohort of Older Adults by Pinsky P.F. (10280336)

“…<b><i>Objective:</i></b> The aim of this study was to determine whether the use of opioids and other medications in a cohort of older adults was associated with self-reported health status. …”

Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate by Ruobing Bai (4860043)

“…HPCTP caused dose-dependent depression-like behaviors (hypoactivity, light-zone avoidance) through suppression of serotonin 1A (5-HT₁A) signaling, supported by decreased <i>htr1aa</i> expression and serotonin levels and partially rescued by the 5-HT₁A receptor agonist 8-OH-DPAT. …”

Childhood Diarrhea Exhibits Spatiotemporal Variation in Northwest Ethiopia: A SaTScan Spatial Statistical Analysis by Muluken Azage (796917)

“…It has spatiotemporal variation and seasonal patterns with a decreasing temporal trend. Accounting for the spatiotemporal variation identified in the study areas is advised for the prevention and control of diarrhea.…”

Depression and Anxiety Outcomes Associated with Failed Assisted Reproductive Technologies: A Systematic Review and Meta-Analysis by Adriana Milazzo (3344186)

“…In contrast, depression decreased after a successful treatment, SMD of -0.24 (95% CI: -0.37,-0.11). …”

Flight Performance and Feather Quality: Paying the Price of Overlapping Moult and Breeding in a Tropical Highland Bird by Maria Angela Echeverry-Galvis (411141)

“…<div><p>A temporal separation of energetically costly life history events like reproduction and maintenance of the integumentary system is thought to be promoted by selection to avoid trade-offs and maximize fitness. …”

DataSheet_1_The isl2a transcription factor regulates pituitary development in zebrafish.xlsx by Chen-Yan Yan (14577641)

“…Additionally, thyrotropes, a pituitary cell type, was notably decreased during development. …”

<i>In Vivo</i> Substrates of the Lens Molecular Chaperones αA-Crystallin and αB-Crystallin by Usha P. Andley (354477)

“…Homozygous αA-R49C mutant lenses exhibited increased associations between αA-crystallin and βB3-, βA4-, βA2-crystallins, and grifin, whereas levels of βB1-crystallin, gelsolin, and calpain 3 decreased. …”

Data_Sheet_1_Middle Cerebellar Peduncle Width—A Novel MRI Biomarker for FXTAS?.PDF by Annie L. Shelton (5445332)

“…Therefore, while the MPRI may not be a useful biomarker for FXTAS, decreased MCP width may be one of the first notable signs of FXTAS, and therefore the first biomarker with the potential to identify those most at risk for the disorder.…”

Table_1_Delay and Speed of Visual Feedback of a Keystroke Cause Illusory Heaviness and Stiffness.XLSX by Takumi Yokosaka (719217)

“…Our results showed that the heaviness and stiffness ratings increased as the delay increased and decreased as the speed increased. To check whether the manipulation of the delay and speed of the visual feedback caused changes in the subjective evaluation of sensorimotor incongruence, in Experiment 2, we asked the participants to give a rating for the sense of agency. …”