Inhibition of MMP-9 secretion was accompanied by an intracellular accumulation of a 92 kDa-MMP-9. by Svantje Tauber (121637)

“…Control cells were treated with vehicle. (a) Upon 24 h treatment with WIN, the amount of MMP-9 in the cell lysate increased, whereas the amount of secreted MMP-9 in the conditioned medium decreased. …”

Effect of the <i>BCAM0223</i> mutation on adherence to extracellular matrix proteins and biofilm formation. A by Dalila Mil-Homens (148922)

“…Either after 24 h or 48 h incubation, the <i>BCAM0223</i> mutant strain exhibited a statistically significant reduction in biofilm formation (*<i>P</i><0.001 and **<i>P</i><0.05). …”

Far-UV CD spectra of pEAβ(3–40) and Aβ(1–40). by Christina Dammers (803567)

“…CD spectra were recorded at 20°C from 260 to 187 nm, accumulated 10 times and background corrected. (a) CD spectra of 25 μM pEAβ(3–40) in 25%, 23%, 22%, 21% and 20% TFE showed a shift from α-helical structure towards β-sheets with decreasing TFE concentrations. …”

In a collagen matrix, axon outgrowth is reduced with <i>TTL^−/−</i> precerebellar neurons. by Séverine Marcos (265144)

“…(B, E) After 1DIV only, the decreased outgrowth was already detectable. Inserts in A, C, D and F show high magnifications of fibers in fascicles that showed a disorganized aspect in the absence of TTL compared to the parralel organization of leading processes inside fascicles in wt. …”

Data_Sheet_1_Pulse Dosing of Antibiotic Enhances Killing of a Staphylococcus aureus Biofilm.pdf by Kirsten J. Meyer (5095925)

“…Our results highlight that a subpopulation of the biofilm survives antibiotic without becoming resistant, a population we refer to as persister bacteria. …”

A systematic review and meta-analysis on the effect social groups have on the egress times of pedestrian crowds by Yanghui Hu (11670788)

“…Our work presents a quantitative basis for discussing the statistical reliability of experiments considering the high context-dependency of pedestrian dynamics.…”

Data Sheet 1_A case report of X-linked hypophosphatemia combined with primary hyperparathyroidism.docx by YinQiong Wu (21803309)

“…<p>Both hypophosphatemic osteomalacia and primary hyperparathyroidism (PHPT) can lead to hypophosphatemia, but their simultaneous occurrence in the same patient is exceedingly rare. This article reports a case of a 43-year-old female patient whose primary clinical manifestations included pain in the lumbosacral and scapular regions, restricted mobility, and biochemical findings of decreased serum phosphate levels with normal parathyroid hormone (PTH) levels. …”

Effects of HA on measurements of CSF and plasma A-syn levels using the 211-FL140 ELISA. by Ryotaro Ishii (718119)

“…HAI pretreatment slightly increased A-syn signals in the majority of CSF samples (A), while the A-syn signals were remarkably decreased in most of the plasma samples (B). …”

Doxorubicin-induced apoptosis in LNCaP cells is associated with a reduction in BIRC6 protein expression. by Christopher G. Low (280918)

“…BIRC6 expression was decreased upon treatment in a time-dependent manner and the reduction precedes apoptosis induction as indicated by PARP cleavage at 24 h.…”

LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates-3 by Guoli Wang (59357)

“…</p> for unreduced data, was done by determining the ability of each approach to find functionally related genes based on the MIPS functional classification. In a, the fraction of correct classifications at level 2 in the MIPS ontology are shown in terms of increasing numbers of gene pairs (i.e., decreasing threshold for correlation). …”

There is a significant activation of p42/44 MAPK following LAD ligation, which is preserved with ARB. by Erhan Ararat (373356)

“…<p>(A) Western blots demonstrate that while the expression of p42/44 MAPK does not change following LAD ligation, there is a significant increase in the phosphorylation (activation) of p42/44 MAPK following LAD ligation in the animals treated with vehicle (CHF), which returns to control levels with losartan therapy (CHF+losartan). …”

Helminth exposure selects for a protective Th2 immune response that simultaneously increases risk for fibrosis. by Shirley B. Russell (822595)

“…Global distribution of helminth species in upper part of figure adapted from Lustigman et al. [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005568#pgen.1005568.ref168" target="_blank">168</a>].…”

Pumping H⁺ or Na⁺ does not offer a sustained selective advantage. by Víctor Sojo (613931)

“…<p>(A) Pumping H⁺ in a membrane with 1% ATPase causes a sustained loss in −ΔG as membrane permeability decreases with 1% pump. …”

Human African Trypanosomiasis Diagnosis in First-Line Health Services of Endemic Countries, a Systematic Review by Patrick Mitashi (116126)

“…We conducted a systematic review of the literature between 1970 and 2011 to assess which diagnostic tools are most suitable for use in first-line health facilities in endemic countries. …”

DataSheet_1_Treatment of Tourette Syndrome With Attention Training Technique—A Case Series.pdf by Anja Schaich (9433958)

“…<p>The existing therapeutic strategies of Tourette syndrome (TS) do not lead to sufficient improvement in a significant number of patients. Recently published studies show that paying attention to tics increases whereas directing attention away decreases tic frequency. …”

Pharmacological inhibition of IGF1R restricts growth of a subset of human T-ALL cell lines. by Samuel Gusscott (2994489)

“…Twenty-seven human T-ALL cell lines were cultured <i>in vitro</i> for 3 days with either (<b>A</b>) IGF1R blocking antibody (CP-751,871; 1 μg/ml) versus PBS vehicle control (mock) or (<b>B</b>) dual IGF1R/InsR tyrosine kinase inhibitor (BMS-754807; 0.5 μM) versus DMSO vehicle control (mock). …”

A model for PFK2 in maintaining PPi homeostasis and balanced catabolism and anabolism in <i>Toxoplasma</i>. by Xuke Yang (10910791)

“…As such, PFK2 serves as a key factor in coordinating the parasites’ catabolic and anabolic activities. …”

Imaging from a man in his 50s diagnosed with World Health Organization grade III oligodendroglioma. by Qing Wang (27728)

“…<p>(A) The T1-weighted post-contrast image shows a lesion with decreased signal intensity. …”

HPV score as a predictor of HPV vaccination in multivariate logistic regression (model 1, n = 84). by Aasith Villavicencio (14475240)

“…<p>HPV Score as a predictor of HPV vaccination in a multivariable logistic regression model containing age, race, ethnicity, educational attainment, current contraceptive use, number of sexual partners, and HPV score. …”

Estimating the predictive power of variables using the area under a receiver operating characteristic curve (AUC). by Afaf El-Ansary (3337326)

“…PC1: first principal component in a principal component analysis used as a multivariate biomarker profile. …”