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49741
Maternal obesogenic diet induces endometrial hyperplasia, an early hallmark of endometrial cancer, in a diethylstilbestrol mouse model
Published 2018“…We show that maternal diet by itself did not lead to ECa initiation in wildtype offspring of the C57Bl/6J mouse strain. While offspring fed a HF/HS post-weaning diet resulted in poor metabolic health and decreased uterine weight (regardless of maternal diet), it did not lead to ECa. …”
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49742
Reduced Virulence of an Extensively Drug-Resistant Outbreak Strain of <i>Mycobacterium tuberculosis</i> in a Murine Model
Published 2014“…<div><p>Bacterial drug resistance is often associated with a fitness cost. Large outbreaks of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB have been described that predominately affect persons with HIV infection. …”
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49743
Table2_Barriers and facilitators of public transport use among people with disabilities: a scoping review.docx
Published 2024“…For example, the unavailability or low volume of auditory announcements in a stop or station or on the public transport vehicle may be a barrier to people with visual disability who rely on hearing the information. …”
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49744
Table_1_Low NAD+ Levels Are Associated With a Decline of Spermatogenesis in Transgenic ANDY and Aging Mice.docx
Published 2022“…The important basic question to what extent ageing-related NAD<sup>+</sup> decline is functionally linked to decreased male fertility has been difficult to address due to the pleiotropic effects of aging, and the lack of a suitable animal model in which NAD<sup>+</sup> levels can be lowered experimentally in chronologically young adult males. …”
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49745
Data_Sheet_2_A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation.docx
Published 2019“…More importantly, in glioma cancer cells (GL-261), compound 1a reduced stemness, by decreasing SOX2 protein levels, while also promoting chemotherapy sensitization. …”
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49746
Image_1_The association between caffeine intake and risk of kidney stones: A population-based study.TIFF
Published 2022“…All data were survey-weighted, and corresponding logistic regression models were performed to examine the associations between caffeine intake and the risk of kidney stones.</p>Results<p>In a fully adjusted model, a per-quartile increase in caffeine intake was associated with a 5.32% decreased risk of kidney stones. …”
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49747
Data_Sheet_1_The Role of Attitude Strength in Behavioral Spillover: Attitude Matters—But Not Necessarily as a Moderator.docx
Published 2020“…<p>Studies on how one behavior affects subsequent behaviors find evidence for two opposite trends: Sometimes a first behavior increases the likelihood of engaging in additional behaviors that contribute to the same goal (positive behavioral spillover), and at other times a first behavior decreases this likelihood (negative spillover). …”
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49748
Table1_In utero methadone exposure permanently alters anatomical and functional connectivity: A preclinical evaluation.xlsx
Published 2023“…Altered neural circuitry, dysregulated network refinement, and diffuse network dysfunction have been implicated in executive function deficits that are common in children with POE. FC may serve as a translatable biomarker in children with POE.</p>…”
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49749
Table_3_A Transcriptomic Model of Postnatal Cardiac Effects of Prenatal Maternal Cortisol Excess in Sheep.pdf
Published 2019“…In order to model corticosteroid effects in the neonate, we created a second model in which cortisol was infused for 12 h per day for a daily infusion of 0.5 mg/kg/d. …”
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49750
Table_2_A Transcriptomic Model of Postnatal Cardiac Effects of Prenatal Maternal Cortisol Excess in Sheep.pdf
Published 2019“…In order to model corticosteroid effects in the neonate, we created a second model in which cortisol was infused for 12 h per day for a daily infusion of 0.5 mg/kg/d. …”
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49751
Image_1_Low NAD+ Levels Are Associated With a Decline of Spermatogenesis in Transgenic ANDY and Aging Mice.tif
Published 2022“…The important basic question to what extent ageing-related NAD<sup>+</sup> decline is functionally linked to decreased male fertility has been difficult to address due to the pleiotropic effects of aging, and the lack of a suitable animal model in which NAD<sup>+</sup> levels can be lowered experimentally in chronologically young adult males. …”
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49752
Nationwide Trends in Cardiac Risk and Mortality in Patients With Incident Type 2 Diabetes: A Danish Cohort Study
Published 2021“…From 1996-1999 to 2008-2011, the 7-year risk of myocardial infarction decreased from 6.9% to 2.8% (adjusted hazard ratio [aHR] 0.39, 95% CI 0.37-0.42), cardiac death from 7.1% to 1.6% (aHR 0.23, 95% CI 0.21-0.24), and all-cause death from 28.9% to 16.8% (aHR 0.68, 95% CI 0.66-0.69). …”
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49753
Data_Sheet_1_A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation.docx
Published 2019“…More importantly, in glioma cancer cells (GL-261), compound 1a reduced stemness, by decreasing SOX2 protein levels, while also promoting chemotherapy sensitization. …”
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49754
Triclosan and triclocarban exposure, infectious disease symptoms and antibiotic prescription in infants—A community-based randomized intervention
Published 2018“…</p><p>Conclusions</p><p>Although randomization to TC-containing wash products was not associated with decreased infectious disease reports by mothers, TCs were associated with decreased antibiotic prescriptions, suggesting a benefit against bacterial infection. …”
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49755
DataSheet_1_Heart rate response to cognitive load as a marker of depression and increased anxiety.pdf
Published 2024“…Task accuracy decreased with increased task difficulty. A strong relationship between PPG-measured heart rate and markers of depression and trait anxiety was observed. …”
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49756
Protective effect of dexmedetomidine against organ dysfunction in a two-hit model of hemorrhage/resuscitation and endotoxemia in rats
Published 2019“…<div><p>Dexmedetomidine (DEX), a selective agonist of α2-adrenergic receptors, has anti-inflammation properties and potential beneficial effects against trauma, shock, or infection. …”
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49757
Targeting glycosphingolipid metabolism as a potential therapeutic approach for treating disease in female MRL/lpr lupus mice
Published 2020“…Whereas other renal diseases characterized by increased GSL levels are thought to be a result of upregulated GSL synthesis, our results suggest elevated hexosylceramides and lactosylceramides in lupus nephritis is a result of increased catabolism of ganglioside GM3 due to significantly increased neuraminidase (NEU) activity. …”
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49758
Table_1_The association between caffeine intake and risk of kidney stones: A population-based study.docx
Published 2022“…All data were survey-weighted, and corresponding logistic regression models were performed to examine the associations between caffeine intake and the risk of kidney stones.</p>Results<p>In a fully adjusted model, a per-quartile increase in caffeine intake was associated with a 5.32% decreased risk of kidney stones. …”
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49759
Data_Sheet_2_A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation.docx
Published 2019“…More importantly, in glioma cancer cells (GL-261), compound 1a reduced stemness, by decreasing SOX2 protein levels, while also promoting chemotherapy sensitization. …”
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49760
Liver ischemia/reperfusion injury, a setting in which the functional mass is reduced and the role of PDE5 inhibitor
Published 2019“…Tada-lafil + I/R group rats undergo a similar pattern of I/R after the treatment with Tadalafil 10 mg/kg, 45 min before ischemia. …”