Time constants of approximating exponents as functions of stimulus level, keeping the relative level of the previous stimulus as a parameter; <i>s</i> (silence)–no previous stimulu... by Vladimir V. Popov (5563067)

Inhibition of DNA-PKcs reduces chemoresistance in RET 9 and RET 51 cells. by Lyle J. Burdine (753645)

Linear relationships between model parameters. by Rodolfo Molina-Peña (332334)

“…<p>Certain linear relationships between CSC self-renewal and differentiation kinetic parameters allow identification of families of feasible solutions: (A) By increasing Φ_2/1 while proportionally decreasing Φ_4/1 a family of feasible model solutions can be found. …”

Shift toward greater pathologic post-myocardial infarction remodeling with loss of the adaptive hypertrophic signaling of alpha1 adrenergic receptors in mice by Che-Chung Yeh (4615582)

“…</p><p>Results</p><p>Alpha1A-AR knockout paradoxically increased post-MI hypertrophy compared to wild type controls (WT), but also increased ventricular dilatation, fibrosis, apoptosis, and 4-week post-MI mortality (64% in AKO vs. 25% in WT, P = 0.02), suggesting a shift toward greater pathologic hypertrophy in the absence of pro-adaptive alpha1A effects. alpha1A-AR knockout increased phospho-p38 levels in the pre-MI myocardium compared to WT (0.55 ± 0.16 vs. 0.03 ± 0.01, P<0.05) but decreased phospho-ERK1/2 post-MI (0.49 ± 0.35 arbitrary units vs. 1.55 ± 0.43 in WT, P<0.05). …”

Decreased <i>CLE41</i> gene expression in <i>clv1-101 clv2-101 rpk</i>2-5 mutant and reduced nematode development on the <i>cle41</i> mutant. by Xiaoli Guo (45754)

Oleic acid (OA) leads to the strong phosphorylation of FAK and AKT in ALDH^high cells, resulting in high proliferation and migration. by Hoe Suk Kim (107279)

“…<p>(A) Representative Western blot of the phosphorylation of FAK, AKT and ERK1/2 in ALDH^high cells and ALDH^low cells treated with OA. …”

Sinupret is a robust activator of CFTR-mediated and calcium-activated Cl^- secretion. by Shaoyan Zhang (363713)

“…Sinupret significantly increased ΔI_SC (in µA/cm²)when compared to controls in both WT (20.7+/−0.9 vs. 5.6+/−0.9, p<0.05) and CFTR^−/− MNSE (ΔI_SC in µA/cm², 10.1+/−1.0 vs. 0.9+/−0.3, p<0.05). …”

<i>Arabidopsis</i> PEX19 is farnesylated. by Margaret M. McDonnell (2175666)

“…<p>(A) Proteins with a C-terminal CaaX motif (Cys-aliphatic-aliphatic-X; where X can be Ser, Met, Ala, Asn, or Cys) can be farnesylated by a protein farnesyl-transferase complex composed of PLP and ERA1, cleaved of the three carboxyl-terminal residues, and methylated (me) on the carboxyl group of the prenylated Cys residue [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0148335#pone.0148335.ref059" target="_blank">59</a>]. …”

The evolution of the differences between the combined and whole global binding-folding energy landscapes as a function of . by Xiakun Chu (151393)

correlation between compounds shown as a heat-map. by Malinee Thanee (8433252)

Size-dependent oscillations in a system with negative feedback. by Wolfgang Giese (589210)

Comparison between MR and PET in a typical case of left ICA obstruction. by Tetsuya Tsujikawa (2824997)

“…<p><b>a)</b> Comparison between PET-CBF and ASL-CBF. …”

Deletion of either copy of the mating type locus, <i>MTL</i>a or <i>MTL</i>α, of either the NSGas or the NSGαs, or the two OBPs, <i>OBP</i>a and <i>OBP</i>α, caused a decrease in virulence of the a/α strain P37039 in the mouse tail injection model for systemic infection. by Thyagarajan Srikantha (188224)

Linearity, depth resolution, and concentration quenching. by Sangly P. Srinivas (1967464)

“…The fluorescence change from background to the new plateau occurs over a transition depth ~ 280 μm (inset on the right). …”

DataSheet_1_Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model.docx by Martin Killian (11717159)

“…<p>Sjögren’s syndrome (SjS) is a frequent systemic autoimmune disease responsible for a major decrease in patients’ quality of life, potentially leading to life-threatening conditions while facing an unmet therapeutic need. …”

A Diverse Family of Host-Defense Peptides (Piscidins) Exhibit Specialized Anti-Bacterial and Anti-Protozoal Activities in Fishes by Scott A. Salger (3072093)

“…Use of the innate immune system to decrease disease related mortalities is a novel alternative to conventional drugs. …”

Vesicle <i>p</i>H fluctuations are constant over a range of <i>p</i>H values. by Apeksha Singh (8174256)

Cell surface expression of VLA-4 and VLA-5 were decreased after a 48 h cell-culture with TKIs while CXCR-4 expression was not affected. by Ludovic Belle (293091)

Video2_Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats.MP4 by Felipe Patricio (13217010)

“…After a period of twenty days, a second surgical procedure was performed to implant a guide cannula into the GPe. …”

Table_3_A single amino acid substitution in the AAA-type ATPase LRD6-6 activates immune responses but decreases grain quality in rice.docx by Junjie Yin (3115497)

“…Here, we characterized a rice spl mutant named spl-A (spotted leaf mutant from A814) that shows autoimmunity, broad-spectrum disease resistance and growth deterioration including decreased rice quality. …”