Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”

LM11A-31 prevents cholinergic dystrophic neurites in cortex of late-stage APP^L/S mice. by Danielle A. Simmons (621167)

“…Quantitative analysis showed that LM11A-31 did not significantly affect the total area (<b><i>C</i></b>) or number (<b><i>D</i></b>) of clusters but did decrease the size or mean area per cluster (<b><i>E</i></b>). …”

Postoperative pulmonary complications during a hospitalization. by Katelyn Morris (13943939)

Behaviors with a significant main effect or interaction. by Grace Hecker (18813445)

The 10 most highly regulated genes in sputum and blood from microarray analysis; a positive fold change  =  increase in frequent exacerbators compared to zero exacerbators, a negative fold change  =  decrease in frequent exacerbators compared to zero exacerbators. by Dave Singh (114223)

“…</p><p>The 10 most highly regulated genes in sputum and blood from microarray analysis; a positive fold change  =  increase in frequent exacerbators compared to zero exacerbators, a negative fold change  =  decrease in frequent exacerbators compared to zero exacerbators.…”

Substitution of a lysine residue at position 8 of two model 9mer H2-K^b epitope precursors leads to a marked decrease of N-terminus trimming by ERAP1 <i>in vitro</i>. by Irini Evnouchidou (375919)

“…Note that in both cases, substituting an alanine for the lysine at position 8, leads to a decrease of N-terminus trimming rate by about 8–10 fold.…”

Behavioural Contagion Explains Group Cohesion in a Social Crustacean by Pierre Broly (228993)

“…Our results indicate that the response to the disturbance of groups decreases with increases in these two variables. Models neglecting social effects cannot reproduce experimental data, attesting that cohesion of aggregation in terrestrial isopods is partly governed by a social effect. …”

Time course of (A) water uptake, (B) leakage of anthocyanins as indexed by the absorbance (520 nm) of the incubation solution; and (C) change in area affected by water soaking. by Grecia Hurtado (10798260)

Photophysical Properties of Platinum(II)−Acetylide Complexes: the Effect of a Strongly Electron-Accepting Diimine Ligand on Excited-State Structure by Christopher J. Adams (1847317)

“…</b> The TRIR data show a decrease of the energy of the CC vibration upon excitation, by about 90 cm⁻¹ in comparison to the ground state, and formation of a new, very intense, and very broad band at 1820 cm⁻¹. …”

Comparison of AED activity in the zebrafish and rodent acute PTZ models. by Tatiana Afrikanova (288839)

“…<p>An AED is indicated as positive for 30-min integration intervals if it significantly (p<0.05) decreased locomotor activity. …”

A proposed model on the role of TrkA signaling in the influenza viral replication and virus-induced airway inflammation. by Vikram Verma (13822961)

The S178A mutation in Paxillin alters adhesion assembly and disassembly. by Mathew E. Berginski (214153)

“…<p>(A and B) The rate of adhesion assembly and disassembly are significantly decreased by the S178A mutation. …”

Scheme of the model: Begin with <i>S</i> prepared cells and a barcode pool containing <i>B</i> unique barcodes identified by nominal numbers. by Nava Leibovich (12908477)

SF12 scores of the subgroups of heartburn (2a) and acid regurgitation (2b) symptom severity after individuals with anxiety or depression were excluded. by Shou-Wu Lee (3625487)

A synopsis of study species and data sources. by Michael D. Hatch (8828060)

Chl a transient curve ‘in different treatments. by Can Huang (564071)

“…DS also caused a decrease in plant Y(I) and Y(II). ETRI and ETRII, and increased Y(NO) and Y(NA) in plants, indicating that DS caused photosystem damage in plants. …”

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for medroxyprogesterone acetate doses in a census of 379 clinics providing services i... by Bradley H. Wagenaar (311527)

Mean trends and system losses due to Ebola virus disease (EVD) outbreak (June 2014–April 2015) for first pentavalent vaccinations in a census of 379 clinics providing services in L... by Bradley H. Wagenaar (311527)

Table_1_Antibiotic and antifungal use in pediatric leukemia and lymphoma patients are associated with increasing opportunistic pathogens and decreasing bacteria responsible for act... by Katherine A. Dunn (13158132)

“…<p>Due to decreased immunity, both antibiotics and antifungals are regularly used in pediatric hematologic-cancer patients as a means to prevent severe infections and febrile neutropenia. …”

Ly49C peptide dependent recognition of H-2K^b decreases with peptides bearing non-polar aliphatic auxiliary anchor residues. by Elsa A. Marquez (766160)