Role of EZH2 and G9a enzymes in histone methylation pattern and in miR-212 expression levels in NSCLC. by Mariarosaria Incoronato (197260)

“…These results suggest that in Calu-1 cells the upregulation of EZH2 and G9a enzymes contributes to increase histone methylation and thus to decrease miR-212 expression levels. …”

The <em>Drosophila melanogaster</em> CHD1 Chromatin Remodeling Factor Modulates Global Chromosome Structure and Counteracts HP1a and H3K9me2 by Lakshmi Bugga (393594)

“…Loss of CHD1 resulted in alterations of chromosome structure and an increase in the heterochromatin protein HP1a, while over-expression of CHD1 disrupted higher order chromatin structure and caused a decrease in levels of HP1a. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure by Wei Meng (505670)

“…Due to the increased polarity at C2, the permeability for these compounds decreased. Further adjustment of the polarity by replacing the N1 2,6-dimethoxyphenyl group with a 2,6-diethylphenyl group and reoptimization for the potency of the C5 pyrroloamides resulted in potent compounds with improved permeability. …”

A homozygous missense variant in <i>VWA2</i>, encoding an interactor of the Fraser-complex, in a patient with vesicoureteral reflux by Amelie T. van der Ven (4782093)

“…We identified a homozygous missense mutation (c.1336C>T, p.Arg446Cys) in the gene <i>Von Willebrand factor A domain containing 2</i> (<i>VWA2</i>). …”

Palladium(II)–<i>N</i>‑Heterocyclic Carbene Complex-Based Electrocatalysts for Hydrogen Evolution Reaction by Geetha Basappa Markandeya (14497596)

“…The developed electrocatalysts exhibit excellent stability for up to 10 h with minimal decrease in efficiency, as indicated by the post-stability linear sweep voltammogram. …”

Palladium(II)–<i>N</i>‑Heterocyclic Carbene Complex-Based Electrocatalysts for Hydrogen Evolution Reaction by Geetha Basappa Markandeya (14497596)

“…The developed electrocatalysts exhibit excellent stability for up to 10 h with minimal decrease in efficiency, as indicated by the post-stability linear sweep voltammogram. …”

Palladium(II)–<i>N</i>‑Heterocyclic Carbene Complex-Based Electrocatalysts for Hydrogen Evolution Reaction by Geetha Basappa Markandeya (14497596)

“…The developed electrocatalysts exhibit excellent stability for up to 10 h with minimal decrease in efficiency, as indicated by the post-stability linear sweep voltammogram. …”

Palladium(II)–<i>N</i>‑Heterocyclic Carbene Complex-Based Electrocatalysts for Hydrogen Evolution Reaction by Geetha Basappa Markandeya (14497596)

“…The developed electrocatalysts exhibit excellent stability for up to 10 h with minimal decrease in efficiency, as indicated by the post-stability linear sweep voltammogram. …”

Macroscopic morphology of 17-4PH-xTiC coatings. by Dian Yu Luo (22656111)

“…Field tests showed that the laser-cladded blades maintained a relatively sharp edge even after harvesting wheat for 120 h, whereas the commercially available heat-treated blades had completely failed. …”

SEM morphology of 17-4PH-xTiC coatings. by Dian Yu Luo (22656111)

“…Field tests showed that the laser-cladded blades maintained a relatively sharp edge even after harvesting wheat for 120 h, whereas the commercially available heat-treated blades had completely failed. …”

XRD patterns of 17-4PH-xTiC coatings. by Dian Yu Luo (22656111)

“…Field tests showed that the laser-cladded blades maintained a relatively sharp edge even after harvesting wheat for 120 h, whereas the commercially available heat-treated blades had completely failed. …”

Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism by Thomas Galbo (197643)

“…Insulin-induction of these genes could, however, be blocked by inhibition of the atypical PKCs (aPKCs). The activity of the Akt-inactivating Protein Phosphatase 2A (PP2A) was increased in the insulin-resistant cells. …”

ZNF804a Regulates Expression of the Schizophrenia-Associated Genes PRSS16, COMT, PDE4B, and DRD2 by Matthew J. Girgenti (180992)

“…We demonstrate that expression of ZNF804a results in a significant increase in transcript levels of PRSS16 and COMT, relative to GFP transfected controls, and a statistically significant decrease in transcript levels of PDE4B and DRD2. …”

Effect of non-linear mixed effects on populations. by Barbara Schnitzer (6246920)

“…Naturally, the populations with equal parameters have a decreased variability in properties like the replicative lifespan and the rejuvenation index. …”

Schematic of experimental equipment and process. by Dian Yu Luo (22656111)

Unmolten particles in the coating. by Dian Yu Luo (22656111)

Distribution Coefficients of the REEs, Sr, Y, Ba, Th, and U between α‑HIBA and AG50W-X8 Resin by Haoyu Li (1672648)

“…For all 19 elements, the distribution coefficients decrease with increasing acid concentration. For the REEs, a linear relationship is observed in log–log space between <i>K</i>_d values and α-HIBA molarity. …”

Table_2_Baf45a Mediated Chromatin Remodeling Promotes Transcriptional Activation for Osteogenesis and Odontogenesis.docx by Theodore Busby (11894552)

“…Furthermore, shRNA-mediated knockdown of Baf45a in odontoblasts leads to markedly altered genes responsible for the proliferation, apoptosis, DNA repair, and modest decrease in dentinogenic marker gene expression. …”