Platelet–Lymphocyte Ratio, Neutrophil–Lymphocyte Ratio and Their Dynamic Changes with Type 2 Diabetes Mellitus: A Cohort Study in China by Canjia Zhang (13866073)

“…</p> <p>PLR exhibited significant correlation with T2DM risk in a linear reverse dose–response pattern, the corresponding HRs and 95% CIs were 0.81 (0.72, 0.90), 0.71 (0.63, 0.80) and 0.56 (0.49, 0.64) respectively (<i>P</i>_trend < 0.001) for Q2, Q3 and Q4 vs Q1 after adjusting for age, gender, BMI, TG, TC, HDL-C, FPG, ALT, AST, heart rate, smoking, family history of diabetes, and alcohol consumption at baseline in Model 3. …”

WT and HIV-1 tg brains were sectioned and stained for Ki-67 reactivity as a measure of cell proliferation. by Christina L. Nemeth (561625)

“…<p>(A) HIV-1 tg brains had significantly decreased levels of cell proliferation in the dentate gyrus of the hippocampus as compared to WT brains (*<i>p</i><0.05). …”

Data_Sheet_1_Optimizing clinical outcomes in polypharmacy through poly-de-prescribing: a longitudinal study.docx by Doron Garfinkel (18465243)

“…Subjective: general satisfaction from de-prescribing; change in functional, mental, and cognitive status; improved sleep quality, appetite, and continence; and decreased pain.</p>Results<p>Mean age: 83 years (range 65–99 years). …”

Data Sheet 2_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment by Adam A. Friedman (812702)

“…We describe the results of a combination screen of an unprecedented scale in mammalian cells performed using a collection of targeted, clinically tractable agents across a large panel of melanoma cell lines. …”

Data_Sheet_1_Associations of lipids and lipid-lowering drugs with risk of stroke: a Mendelian randomization study.ZIP by Hao Qin (113159)

“…The IVW-MR also found a suggestive evidence that decreased LDL-C levels mediated by the PCSK9 (proprotein convertase subtilisin-kexin type 9) gene were associated with a reduced risk of any stroke (AS) (OR, 1.31; 95% CI, 1.13–1.52; p = 0.0003), any ischemic stroke (AIS) (OR, 1.29; 95% CI, 1.10–1.51; p = 0.001), and LAS (OR, 1.73; 95% CI, 1.15–2.59; p = 0.008), while NPC1L1 (Niemann-Pick C1-like protein)-mediated LDL-C levels were associated with a higher risk of small vessel stroke (SVS) (OR, 6.10; 95% CI, 2.13–17.43; p = 0.0008). …”

Table1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.xlsx by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

Datasheet1_The role of circulating cytokines in heart failure: a bidirectional, two-sample Mendelian randomization study.pdf by Haoran Zheng (388894)

“…This study draws further conclusions at the genetic level, providing a basis for future large-scale clinical trials.…”

DataSheet_1_Cascading effects of seed-stem-individual spatial patterns along a grazing gradient.docx by Zhou Qin-Yuan (14792533)

“…The results showed the following: (1) Seed size increased with increasing grazing intensity, and the coefficient of variation for seed size and seed number in the heavy grazing treatment was greater than 0.6. (2) The structural equation model showed that grazing treatment had a positive effect on seed number, seed size and reproductive stem number and a negative effect on reproductive stem weight. (3) Grazing treatment did not affect the resource allocation to reproductive stems and vegetative stems per unit length of reproductive K. humilis individuals. (4) Compared with the number of reproductive individuals in the no grazing treatment, the number in the heavy grazing treatment decreased significantly, and the negative correlation between reproductive individuals and nonreproductive individuals changed from a full-scale negative correlation to a small-scale negative correlation and a large-scale positive correlation. …”

Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Child Mortality Estimation: A Comparison of UN IGME and IHME Estimates of Levels and Trends in Under-Five Mortality Rates and Deaths by Leontine Alkema (111799)

“…<div><h3>Background</h3><p>Millennium Development Goal 4 calls for a reduction in the under-five mortality rate (U5MR) by two-thirds between 1990 and 2015. …”

Table_2_Neoadjuvant chemoradiotherapy combined with immunotherapy for locally advanced rectal cancer: A new era for anal preservation.xlsx by Yaqi Wang (1555240)

“…It was demonstrated to decrease the local recurrence rate and increase the tumor response grade. …”

Table_1_Oxidative balance score: a potential tool for reducing the risk of colorectal cancer and its subsites incidences.docx by Yu Chang (392011)

“…The objective of this study was to assess the relationship between OBS and the risk of CRC, its subsites, and common complications in a large prospective cohort study.</p>Methods<p>We included data from 175,808 participants in the UK Biobank data sample repository from 2006 to 2010. …”

Table_1_Neoadjuvant chemoradiotherapy combined with immunotherapy for locally advanced rectal cancer: A new era for anal preservation.xlsx by Yaqi Wang (1555240)

“…It was demonstrated to decrease the local recurrence rate and increase the tumor response grade. …”

DataSheet_1_The association of lipid metabolism with bone metabolism and the role of human traits: a Mendelian randomization study.docx by Jian Kang (118630)

“…</p>Results<p>The results showed that a 1 standard deviation(SD) increase in HDL-C, LDL-C and TC was associated with a decrease in LS-BMD of 0.039 g/cm², 0.045 g/cm² and 0.054 g/cm², respectively. …”

DataSheet_2_The association of lipid metabolism with bone metabolism and the role of human traits: a Mendelian randomization study.xlsx by Jian Kang (118630)

“…</p>Results<p>The results showed that a 1 standard deviation(SD) increase in HDL-C, LDL-C and TC was associated with a decrease in LS-BMD of 0.039 g/cm², 0.045 g/cm² and 0.054 g/cm², respectively. …”

Presentation_1_Contrasting Effects of Long-Term Nitrogen Deposition on Plant Phosphorus in a Northern Boreal Forest.pdf by Kristin Palmqvist (3140016)

“…We therefore conclude that increased NP ratio of vegetation cannot be used as a sole indicator of P limitation. The vegetation and O-horizon changes in N2 were still large enough to merit further studies addressing whether such high N loads may alter ecosystem biogeochemistry toward P limitation. …”

The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study by Donald A. Belcher (4836420)

“…In addition, we found that PolyhHb transfusion decreased the wall shear stress at large arteriole diameters (>20 μm), but increased wall shear stress for small arteriole diameters (<10 μm). …”

Data Sheet 1_First-in-human study of CPL’116 – a dual JAK/ROCK inhibitor – in healthy subjects.docx by Piotr J. Rudzki (20970821)

“…A decrease in MLC phosphorylation indicated a potential trend at p < 0.1.…”

Image_1_Exercise Promotion and Distress Reduction Using a Mobile App-Based Community in Breast Cancer Survivors.TIF by Il Yong Chung (3804493)

“…This study aimed to investigate the effect of a mobile app-based community on enhancing PA and decreasing distress in breast cancer survivors. …”