Coupling of an Acyl Migration Prodrug Strategy with Bio-activation To Improve Oral Delivery of the HIV‑1 Protease Inhibitor Atazanavir by Murugaiah A. M. Subbaiah (5141450)

“…This strategy was refined by conjugating the amine with a promoiety designed to undergo bio-activation, as a means of modulating the subsequent chemo-activation. …”

Table_1.docx by Marco A. Molina-Montenegro (301997)

“…Overall, thickness of seed coat (plus wall achene) decreases with latitude, indicating that individuals of T. officinale from northern populations have a thicker seed coat than those from southern populations. …”

The Diamine Oxidase Gene Is Associated with Hypersensitivity Response to Non-Steroidal Anti-Inflammatory Drugs by José A. G. Agúndez (119973)

“…Analyses of the SNPs rs17740607, rs2073440, rs1801105, rs2052129, rs10156191, rs1049742 and rs1049793 in the <em>HDC</em>, <em>HNMT</em> and <em>DAO</em> genes were carried out by means of TaqMan assays. The detrimental DAO 16 Met allele (rs10156191), which causes decreased metabolic capacity, is overrepresented among patients with crossed-hypersensitivity to NSAIDs with an OR  = 1.7 (95% CI  = 1.3–2.1; Pc  = 0.0003) with a gene-dose effect (P = 0.0001). …”

Edelfosine is taken up by macrophages and inhibits macrophage-derived inflammatory mediators. by Janny A. Villa-Pulgarín (4381723)

“…(<b>D-F</b>) BMM from edelfosine-fed mice show a decreased generation of inflammatory mediators. …”

Spatial patterns of water-dispersed seed deposition along stream riparian gradients by Rob G. A. Fraaije (3258822)

“…Community-weighted trait means indicated that typically water-dispersed seeds were more dominant in flooded than in non-flooded seed traps and gradually decreased in concentration from the channel to the upland. …”

<i>In vitro</i> and <i>in vivo</i> antileishmanial activity of the antitumor ether phospholipid edelfosine. by Janny A. Villa-Pulgarín (4381723)

“…<p>Apoptosis-like cell death was quantitated by flow cytometry as percentage of hypodiploid cells (sub-G₀/G₁) in different <i>Leishmania</i> spp. promastigotes (<b>A</b>) and human cancer cell lines (myeloid leukemia HL-60, multiple myeloma MM144, and cervical carcinoma HeLa) (<b>B</b>), following 24-h incubation with distinct APLs (10 μM). …”

Nearly 1000 Protein Identifications from 50 ng of <i>Xenopus laevis</i> Zygote Homogenate Using Online Sample Preparation on a Strong Cation Exchange Monolith Based Microreactor Co... by Zhenbin Zhang (1444888)

“…A sulfonate–silica hybrid strong cation exchange monolith microreactor was synthesized and coupled to a linear polyacrylamide coated capillary for online sample preparation and capillary zone electrophoresis-tandem mass spectrometry (CZE-MS/MS) bottom-up proteomic analysis. …”

<b>Effects of </b><b>D</b><b>ifferent </b><b>L</b><b>evels of </b><b>Lycium </b><b>R</b><b>uthenicum</b><b> </b><b>L</b><b>eaves on </b><b>R</b><b>umen </b><b>F</b><b>ermentation,... by Jinlong Li (20481890)

“…Moreover, the contents of non-essential amino acids, sweet amino acids, and total amino acids in meat linearly increased with increasing dietary LRL levels (P<0.05). (5) The content of C17:0 in meat was decreased in the LRL5% group (P<0.05), while the content of C20:1 was increased in the LRL10% group (P<0.05). …”

Effect of compound 4f on (A) Platelet aggregation induced by Collagen/ADP/Epinephrine and (B) Platelet adhesion on immobilized collagen type I with compound 4f pre-treated collagen... by Kodagahalli S. Rakesh (631835)

DataSheet_1_Free Versus Fixed-Ratio Combination of Basal Insulin and GLP-1 Receptor Agonists in Type 2 Diabetes Uncontrolled With GLP-1 Receptor Agonists: A Systematic Review and I... by Han Na Jung (9942484)

“…Both approaches significantly lowered HbA1c levels (weighted mean difference [WMD] −0.75%, 95% CI −0.97 to −0.53) but increased hypoglycemic risk [risk ratio (RR) 7.59, 95% CI 3.35−17.17] compared to the unchanged GLP-1RA. …”

Genetic deletion of P2rx7 leads to the alteration of NA and 5-HT levels (A, B), elevation of³H-Citalopram binding sites and 5-HT uptake (C) in the mouse hippocampus. by Cecilia Csölle (425362)

“…<p>A, B/NA and 5-HT levels were analyzed using HPLC in the hippocampus of naive and LPS (1 mg/kg)-treated P2rx7+/+ and P2rx7−/− mice. …”

Table_3_Quantity and Quality of Healthcare Professionals, Transfer Delay and In-hospital Mortality Among ST-Segment Elevation Myocardial Infarction: A Mixed-Method Cross-Sectional... by Qiang Zhou (29805)

“…Based on a sample of 31 hospitals, 1,255 healthcare professionals, and 3,131 patients with STEMI, a generalized linear model was used to explore the associations between the quality and quantity of healthcare professionals and transfer delay and in-hospital mortality among STEMI patients. …”

Table_2_Quantity and Quality of Healthcare Professionals, Transfer Delay and In-hospital Mortality Among ST-Segment Elevation Myocardial Infarction: A Mixed-Method Cross-Sectional... by Qiang Zhou (29805)

“…Based on a sample of 31 hospitals, 1,255 healthcare professionals, and 3,131 patients with STEMI, a generalized linear model was used to explore the associations between the quality and quantity of healthcare professionals and transfer delay and in-hospital mortality among STEMI patients. …”

Table_1_Quantity and Quality of Healthcare Professionals, Transfer Delay and In-hospital Mortality Among ST-Segment Elevation Myocardial Infarction: A Mixed-Method Cross-Sectional... by Qiang Zhou (29805)

“…Based on a sample of 31 hospitals, 1,255 healthcare professionals, and 3,131 patients with STEMI, a generalized linear model was used to explore the associations between the quality and quantity of healthcare professionals and transfer delay and in-hospital mortality among STEMI patients. …”

S3 Fig - by Yaqi Wang (1555240)

Table2_The impact of sport-specific physical fitness change patterns on lower limb non-contact injury risk in youth female basketball players: a pilot study based on field testing... by Yuanqi Huang (7301531)

“…Feature extraction was performed on the dataset using linear discriminant analysis, and the prediction model was constructed using the cost-sensitive neural network.…”

Table1_The impact of sport-specific physical fitness change patterns on lower limb non-contact injury risk in youth female basketball players: a pilot study based on field testing... by Yuanqi Huang (7301531)

“…Feature extraction was performed on the dataset using linear discriminant analysis, and the prediction model was constructed using the cost-sensitive neural network.…”

<b>Supplementary Table S1. </b>Changes in anthropometric measures and lipids during treatment with gonadotropin-releasing hormone analog (GnRHa) monotherapy were analyzed using mix... by Kjersti Kvernebo Sunnergren (8104385)

“…<p dir="ltr">Note: All estimates are given as changes from the baseline and only calculated if more than five samples were available at a given time. A negative estimate indicates a decrease from baseline, and a positive estimate suggests an increase. …”

Figure S1 - A Prolyl-Hydroxylase Inhibitor, Ethyl-3,4-Dihydroxybenzoate, Induces Cell Autophagy and Apoptosis in Esophageal Squamous Cell Carcinoma Cells via Up-Regulation of BNIP3... by Bo Han (84102)

“…<p><b>Gene expression profile analysis of EDHB-treated KYSE 170 cells.</b> (A) Heat map of overlapping genes. Red/green indicate an increase/decrease in gene expression relative to the universal mean for each gene. …”

Glucagon-like peptide 1 receptor agonists modestly reduced low-density lipoprotein cholesterol and total cholesterol levels independent of weight reduction: a meta-analysis and met... by Frederick Berro Rivera (12679463)

“…Data extraction and quality assessment were performed, and outcomes were analyzed using a random-effects model to calculate weighted mean differences (MDs) in milligrams per deciliter (mg/dl) and 95% confidence intervals (CIs). …”