The role of <i>neuromedin U</i> in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort by Francesco Gianfagna (440763)

“…We analysed the associations between <i>NMU</i> gene variants and haplotypes and body mass index (BMI) in a large sample of European children.</p><p>Methods and results</p><p>From a large European multi-center study on childhood obesity, 4,528 children (2.0–9.9 years, mean age 6.0±1.8 SD; boys 52.2%) were randomly selected, stratifying by age, sex and country, and genotyped for tag single nucleotide polymorphisms (SNPs; rs6827359, T:C; rs12500837, T:C; rs9999653,C:T) of <i>NMU</i> gene, then haplotypes were inferred. …”

EGCG effects on CUMS–induced changes in ultra-structure and autophagic flux in CA1. by Hong-Feng Gu (287123)

“…<p>TEM and western blotting were conducted to evaluate autophagic flux. (A) TEM was used to examine autophagosome formation. …”

Data_Sheet_1_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.docx by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”

Image_2_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.TIF by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”

Telomere length regulates Fst/BMP/pSmad signaling. by Na Liu (102929)

“…<p>(A) Scatter plots showing global differential gene expression profile of WT and G4 <i>Terc</i>^–/–ES cells. …”

Image_2_Glucose Metabolism Reprogramming of Primary Tumor and the Liver Is Associated With Disease-Free Survival in Patients With Early NSCLC.tif by Hongpei Tan (11616760)

“…Purpose<p>Tumor promote disease progression by reprogramming their metabolism and that of distal organs, so it is of great clinical significance to study the changes in glucose metabolism at different tumor stages and their effect on glucose metabolism in other organs.</p>Methods<p>A retrospective single-centre study was conducted on 253 NSCLC (non-small cell lung cancer) patients with negative lymph nodes and no distant metastasis. …”

Image_3_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.TIF by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”

PbCBP-O is required for efficient midgut traversal. by Dominika Kwecka (22170493)

“…<p><b>(A)</b> PbΔCBP-O ookinetes show regular motility. …”

IKKε interacts with PML and disrupts the PML nuclear bodies. by Xiaoqian Wang (460263)

“…<p>(<i>A</i>) IKKε interacts with PML. HEK293T cells were co-transfected with indicated plasmids and cell lysates were subjected to IP and IB with indicated antibodies. …”

E1AF involved in the mouse FAK gene transcription activation in B16F1 cells. by Shufeng Li (48761)

“…<p>(A) Activation of FAK promoter by ETS transcription factor E1AF. …”

Inter-rater agreement of AGREE II domains. by Gustavo Angel (14676166)

Image_3_Glucose Metabolism Reprogramming of Primary Tumor and the Liver Is Associated With Disease-Free Survival in Patients With Early NSCLC.tif by Hongpei Tan (11616760)

“…Purpose<p>Tumor promote disease progression by reprogramming their metabolism and that of distal organs, so it is of great clinical significance to study the changes in glucose metabolism at different tumor stages and their effect on glucose metabolism in other organs.</p>Methods<p>A retrospective single-centre study was conducted on 253 NSCLC (non-small cell lung cancer) patients with negative lymph nodes and no distant metastasis. …”

RTEF-1 induces angiogenesis in endothelial cells. by Ping He (33281)

“…<p><b>A.</b> RTEF-1 was over-expressed in HMEC-1. RTEF-1 mRNA (left) and protein (right) were detected in control HMEC-1 and RTEF-1 o/e HMEC-1. (** = <i>p</i><0.01, <i>vs</i> control HMEC-1) <b>B.…”

Image_1_Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.TIFF by Tao Qian (1480588)

“…The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m². Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). …”

Motivation for return to work and actual return to work among people on long-term sick leave due to pain syndrome or mental health conditions by Lars Carlsson (10323)

“…</p> <p><b>Materials and methods:</b> Data by responses to questionnaires was collected from 227 people on long-term sick leave (mean = 7.9 years) due to pain syndrome or mild to moderate mental health conditions who had participated in a vocational rehabilitation intervention. …”

Forecasting the Impacts of Silver and Bighead Carp on the Lake Erie Food Web by Hongyan Zhang (618068)

“…Relative to baseline simulations without AC, AC invasion under all detrital diet scenarios decreased the biomass of most fish and zooplankton groups. …”

Up-regulation of IFNγ-producing Vγ2Vδ2 T effector cells after HMBPP stimulation coincided with the down-regulated capacity of T cells to produce IL-22 <i>de novo</i>. by Shuyu Yao (252505)

“…<p>(<b>A</b>) Representative paired flow-cytometry histograms from monkey RH7406 (lung), RH7720 (spleen), RH7357 (mesenteric lymph node) show intracellular cytokine staining data indicating that HMBPP stimulation up-regulated numbers of CD3+ IFNγ+Vγ2+ T cells (right) and down-regulated numbers of CD3+IL-22+ T cells (left) in lymphocytes from lungs, spleens and mesenteric lymph nodes (LN). …”

Image_1_Glucose Metabolism Reprogramming of Primary Tumor and the Liver Is Associated With Disease-Free Survival in Patients With Early NSCLC.tif by Hongpei Tan (11616760)

“…Purpose<p>Tumor promote disease progression by reprogramming their metabolism and that of distal organs, so it is of great clinical significance to study the changes in glucose metabolism at different tumor stages and their effect on glucose metabolism in other organs.</p>Methods<p>A retrospective single-centre study was conducted on 253 NSCLC (non-small cell lung cancer) patients with negative lymph nodes and no distant metastasis. …”

Inhibition of tumorgeneic activity in Oct-4 siRNA-treated LC-CD133⁺ with chemoradiotherapy. by Yu-Chih Chen (151468)

“…<p>LC-CD133⁺-GFP (10⁴) cells of different treatment groups were injected into the subcutaneous sites of nude mice. (A) The tumor volume and (B) The number of pulmonary tumor nodules were significantly decreased in Oct-4 siRNA-treated LC-CD133⁺ when exposed to IR alone, cisplatin alone, or IR combined with cisplatin. …”

Ribosome footprinting and polysome profiling reveal DUX4 suppressive effects on translation efficiency. by Danielle C. Hamm (4693915)

“…(<b>I</b>) Log2 fold-change in polysome abundance of MHC-I mRNAs, iProteasome subunits, select TOP mRNAs, and myogenic factors. Data represent mean ± SD of biological replicates, <i>n =</i> 3; see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002317#pbio.3002317.s012" target="_blank">S4 Data</a>. …”