Image2_First-in-Human, Double-Blind, Randomized, Placebo-Controlled Trial of TQ-F3083, a New Dipeptidyl Peptidase-4 Inhibitor, in Healthy Chinese Adults.TIF by Jingrui Liu (1694983)

“…The accumulation factor was 1.39 after multiple dose for 7 days. Decreased plasma exposure (84.87% decrease in C_max, 49.23% in AUC_0-t, and 47.77% in AUC_0-∞) was observed with administration after a high-fat and high-calorie standardized breakfast. …”

Image1_First-in-Human, Double-Blind, Randomized, Placebo-Controlled Trial of TQ-F3083, a New Dipeptidyl Peptidase-4 Inhibitor, in Healthy Chinese Adults.TIF by Jingrui Liu (1694983)

“…The accumulation factor was 1.39 after multiple dose for 7 days. Decreased plasma exposure (84.87% decrease in C_max, 49.23% in AUC_0-t, and 47.77% in AUC_0-∞) was observed with administration after a high-fat and high-calorie standardized breakfast. …”

Image3_First-in-Human, Double-Blind, Randomized, Placebo-Controlled Trial of TQ-F3083, a New Dipeptidyl Peptidase-4 Inhibitor, in Healthy Chinese Adults.TIF by Jingrui Liu (1694983)

“…The accumulation factor was 1.39 after multiple dose for 7 days. Decreased plasma exposure (84.87% decrease in C_max, 49.23% in AUC_0-t, and 47.77% in AUC_0-∞) was observed with administration after a high-fat and high-calorie standardized breakfast. …”

DataSheet1_A mechanistic physiologically based model to assess the effect of study design and modified physiology on formulation safe space for virtual bioequivalence of dermatolog... by J. F. Clarke (14200124)

“…The tested dosing scenarios showed decreased sensitivity for all formulation parameters with a decreased dose. …”

DataSheet1_A mechanistic physiologically based model to assess the effect of study design and modified physiology on formulation safe space for virtual bioequivalence of dermatolog... by J. F. Clarke (14200124)

“…The tested dosing scenarios showed decreased sensitivity for all formulation parameters with a decreased dose. …”

<i>AtFLL2</i>, a member of the <i>FLO2</i> gene family, affects the enlargement of leaves at the vegetative stage and facilitates the regulation of carbon metabolism and flow by Nonoka Sato (9353791)

“…The expression levels of genes involved in biosynthesis of sucrose and starch were largely altered. These results suggest that, in the <i>fll2</i> mutant, a small amount of photosynthetic products was used for the biosynthesis of starch, and the products were supplied to promote intracellular growth of the source organs or for transport to the sink organs. …”

Enlargement of widespread fibrovascular tissue (disease progression) before the development of massive subretinal hemorrhage (SRH) in Patient 4, a 65-year-old woman with retinal an... by Jae Hyung Lee (1703224)

“…Eight ranibizumab injections were performed during the follow-up period, and best-corrected visual acuity (BCVA) of the left eye decreased, from 20/100 to 20/160. (F) Late-phase ICGA revealed a large plaque lesion at the macula, indicating the enlarged fibrovascular tissue complex. …”

Duplex ddPCR for <i>IGF1</i> and <i>EPO</i> transgene elements. by Dirk A. Moser (655732)

“…<p>500 ng human gDNA were spiked with serial dilutions (1∶5; 1∶2; 1∶5; 1∶2 and 1∶5) of <i>IGF1</i>-standard (A), decreasing amounts of <i>IGF1</i> and <i>EPO</i>-standard (B), inverse amounts of <i>IGF1</i> (decreasing) and <i>EPO</i> (increasing) (C), <i>EPO</i> only (D) and <i>IGF1</i> multiplexed with ICS at ∼100 copies/reaction (E). …”

Table_1_Effect of Organic Fe-Ligands, Released by Emiliania huxleyi, on Fe(II) Oxidation Rate in Seawater Under Simulated Ocean Acidification Conditions: A Modeling Approach.DOCX by Guillermo Samperio-Ramos (5397125)

“…The organic ligands present in the coccolithophorid exudates were responsible for this decrease. The oxidation of Fe(II) in artificial seawater was also investigated at nanomolar levels over a range of pH (7.75–8.25) at 25°C in the presence of different glucuronic acid concentrations. …”

Image_2_Effect of Organic Fe-Ligands, Released by Emiliania huxleyi, on Fe(II) Oxidation Rate in Seawater Under Simulated Ocean Acidification Conditions: A Modeling Approach.TIF by Guillermo Samperio-Ramos (5397125)

“…The organic ligands present in the coccolithophorid exudates were responsible for this decrease. The oxidation of Fe(II) in artificial seawater was also investigated at nanomolar levels over a range of pH (7.75–8.25) at 25°C in the presence of different glucuronic acid concentrations. …”

Image_1_Effect of Organic Fe-Ligands, Released by Emiliania huxleyi, on Fe(II) Oxidation Rate in Seawater Under Simulated Ocean Acidification Conditions: A Modeling Approach.TIF by Guillermo Samperio-Ramos (5397125)

“…The organic ligands present in the coccolithophorid exudates were responsible for this decrease. The oxidation of Fe(II) in artificial seawater was also investigated at nanomolar levels over a range of pH (7.75–8.25) at 25°C in the presence of different glucuronic acid concentrations. …”

Table_2_Tumor growth manifested in two-fifths of low-risk papillary thyroid microcarcinoma patients during active surveillance: data from a tertiary center in China.docx by Kehao Le (8533776)

“…</p>Conclusion<p>TDR may be a better metric for evaluating tumor growth in observational PTMCs. …”

Table_1_Tumor growth manifested in two-fifths of low-risk papillary thyroid microcarcinoma patients during active surveillance: data from a tertiary center in China.xlsx by Kehao Le (8533776)

“…</p>Conclusion<p>TDR may be a better metric for evaluating tumor growth in observational PTMCs. …”

Edge-Reconstructed, Few-Layered Graphene Nanoribbons: Stability and Electronic Properties by Juliana A. Gonçalves (3813442)

“…We find that the nanoribbon stability increases linearly with increasing width and decreases linearly with increasing number of layers (from three to six layers). …”

Presentation_2_Amoxicillin Increased Functional Pathway Genes and Beta-Lactam Resistance Genes by Pathogens Bloomed in Intestinal Microbiota Using a Simulator of the Human Intestin... by Lei Liu (5074)

Presentation_3_Amoxicillin Increased Functional Pathway Genes and Beta-Lactam Resistance Genes by Pathogens Bloomed in Intestinal Microbiota Using a Simulator of the Human Intestin... by Lei Liu (5074)

Presentation_1_Amoxicillin Increased Functional Pathway Genes and Beta-Lactam Resistance Genes by Pathogens Bloomed in Intestinal Microbiota Using a Simulator of the Human Intestin... by Lei Liu (5074)

Table_1_Amoxicillin Increased Functional Pathway Genes and Beta-Lactam Resistance Genes by Pathogens Bloomed in Intestinal Microbiota Using a Simulator of the Human Intestinal Micr... by Lei Liu (5074)

Data_Sheet_1_Prior water availability modifies the effect of heavy rainfall on dengue transmission: a time series analysis of passive surveillance data from southern China.pdf by Qu Cheng (849777)

“…In contrast, a heavy rainfall lag of 7–121 days decreased dengue risk when prior water availability was high, with the lowest IRR of 0.59 (95% CI: 0.43–0.79), occurring at a lag of 45 days.…”

Figure S4 from Downregulation of MicroRNA-644a Promotes Esophageal Squamous Cell Carcinoma Aggressiveness and Stem Cell–like Phenotype via Dysregulation of PITX2 by Jia-Xing Zhang (695737)

“…Restoration of PITX2 in miR-644a-overexpressing Eca-109 cells largely rescued the cells' stemness, while knockdown of PITX2 by shPITX2 decreased Eca-109 cells' stemness (A-D). …”