Image_5_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

“…The CA-074 Me-mediated increase of Aβ_1−x, but not the decrease of Aβ_2−x, was influenced by concomitant treatment with the vacuolar H⁺-ATPase inhibitor Bafilomycin A1. …”

The Association between Polypharmacy and Dementia: A Nested Case-Control Study Based on a 12-Year Longitudinal Cohort Database in South Korea by Hae-Young Park (785336)

“…<div><p>Dementia is a major concern among growing chronic diseases in the aging society and its association with polypharmacy has not been adequately assessed. …”

Dynamic modelling of an <i>ACADS</i> genotype in fatty acid oxidation – Application of cellular models for the analysis of common genetic variants by Kerstin Matejka (6729155)

“…Next, we modelled gradual decrease of ACADS expression using a tetracycline-regulated shRNA-knockdown of ACADS in Huh7 hepatocytes, a cell line with high fatty acid oxidation-(FAO)-capacity. …”

Salinomycin decreases the CD44⁺/CD24^- stem-like population during anchorage-independent growth and inhibits mammosphere formation. by Hyunsook An (821121)

Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein but increases of intrathecal axonal degradation products and TGF-β in patients with cerebral lupus by Estelle Trysberg (58614)

“…</p> Cerebrospinal fluid (CSF) content of soluble amyloid β-protein (Aβ42) in patients with systemic lupus erythematosus (SLE) with and without central nervous system (CNS) engagement, as well as in cerebrally healthy control subjects. …”

Mean (Standard Deviation) at baseline and follow-up for strength. by Elora C. Brenneman (795723)

Mean (Standard Deviation) at baseline and follow-up for mobility performance. by Elora C. Brenneman (795723)

Results related to aim 1: Knowledge about the spread of infection, vulnerable patient groups and protection against a virus, and protective gear, among manual therapists in Sweden,... by Iben Axen (21433652)

NREM 1/f slopes calculated from Power Spectrum Densities (PSDs) have a robust nocturnal rhythm at low frequencies that are initially flattened during spontaneous oxycodone withdraw... by Michael Gulledge (20577135)

Effect of previous administration of extended-release buprenorphine (1 mg/kg SC) or saline in rats using a warm-water tail flick assay to assess acute thermal nociception. by Christina M. Larson (18196213)

“…*P < 0.05, **P < 0.01. A) Efficacy in response to standard buprenorphine at 1 mg/kg and 3 mg/kg was significantly decreased in rats previously exposed to extended-release buprenorphine (Bupe ER) vs. those exposed to saline. …”

Competition experiments between the Δ<i>phoP</i> and the Δ<i>corA</i>F044<i>phoP</i> mutants of <i>Salmonella</i>. by Selma Metaane (12329248)

Change from full-scale to reduced model in sum (across all time points and grids) of squared error between simulation and MC scan data as a function of threshold elevation. by Monica E. Shapiro (22622240)

The flow cytometry analysis for Caco-2 cells which had been cultured for 24 hours (A–F), 48 hours (G–L), or 72 hours (M–R) in CM. by Kitjasit Promsut (18823872)

Integration of Metabolomics, Transcriptomics, and 16s rRNA Sequencing Reveals the Mechanism of Morus alba <i>L.</i> (Sangzhi) Alkaloids (SZ-A) in Improving Cholesterol Metabolism i... by Caina Li (4126462)

“…The results showed that repeated treatment with 200 mg/kg SZ-A significantly decreased the total cholesterol and low-density lipoprotein cholesterol levels in the blood and increased the fecal content of two conjugated bile acids, taurodeoxycholic acid (TDCA) and taurolithocholic acid (TLCA). …”

Changes of SOD (A), POD (B), CAT (C) and PRO (D) of overexpressed <i>DlERF10</i> tobacco and wild-type tobacco under low-temperature stress. by Ruijin Zhou (15918112)

Anticipated COVID-19-related stigma among a representative sample of adults residing within the AHDSS¹ from Aug-Oct. 2020 and Aug.-Oct. 2021. by Duduzile P. Mashinini (19173517)

(a) Daily maximum and minimum temperature and (b) mean (± SE) photosynthetic photon flux density (PPFD) in the glasshouse during flowering and fruit set of Redlands Joy, Sugarbaby... by Cao Dinh Dung (11401910)

<i>P2RX7</i> ablation improves <i>mdx</i> muscle strength and endurance and object recognition memory and decreases anxiety in vivo. by Anthony Sinadinos (694160)

Melatonin decreased NADP⁺/NADPH Ratio and the expression of p47phox and gp91phox subunit of NADPH oxidase in prorenin-treated microglia. by Li Hu (326656)

“…(A) The mRNA level of 6 subunits of NADPH oxidase were measured in different treated groups. …”

The spinal cords show decreased microglial reaction in mice transplanted with L1 overexpressing SENAs when compared to wild-type SENAs and sham-injected PBS. by Yi-Fang Cui (227234)