Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain by Jara Teresa Parrilla-Doblas (3825424)

“…<p>DNA methylation is a crucial epigenetic mark associated to gene silencing, and its targeted removal is a major goal of epigenetic editing. …”

Spray Combustion and Particulate Matter Emissions of a Wood Derived Fast Pyrolysis Liquid-Ethanol Blend in a Pilot Stabilized Swirl Burner by Tommy Tzanetakis (1274520)

“…Increasing the residence time of spray droplets in the hot combustion zone by increasing the swirl number promotes the burnout of solid residues. Decreasing the mean diameter of fuel droplets by increasing the atomizing air flow rate has a similar effect. …”

Abrogation of zebrafish <i>lbx2</i> results in a defective s<i>df1a</i> expression pattern in the horizontal myoseptum. by Xiaowen Chen (192197)

“…(K, L) Magnified views of the expression patterns shown in I (K) and J (L), showing decreased numbers of <i>eng2a</i> positive muscle pioneer cells in <i>lbx2</i> morphants (L) compared to control embryos (K). …”

The representation of the MIPS FunCats in the functionally annotated genes in the wild-type <i>A. nidulans</i> genome (A) and the genes differentially expressed (<i>p</i><0.001) in... by Ana Cristina Colabardini (385464)

“…Real-time RT-PCR for AN6669 and AN8737 genes with increased and decreased mRNA accumulation in the wild-type and <i>alcA::ypkA</i> mutant strains grown in glucose 4% or threonine 100 mM, respectively, for 16 and 24 hours.…”

Image_2_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…<p>A comprehensive understanding of the dynamic changes in interleukin-6 (IL-6) levels is essential for monitoring and treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). …”

Image_6_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…<p>A comprehensive understanding of the dynamic changes in interleukin-6 (IL-6) levels is essential for monitoring and treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). …”

Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers by Marie N. S. Gendy (5797325)

“…<div><p>Previous pre-clinical studies demonstrated a promising role of alpha-type peroxisome proliferator-activated receptors (PPARα) agonists in decreasing nicotine self-administration and nicotine-seeking behavior in animals. …”

Image1_Dietary fiber modulates gut microbiome and metabolome in a host sex-specific manner in a murine model of aging.TIFF by Saurabh Kadyan (11383020)

“…The findings demonstrate that inulin exerts prebiotic effects, but in a sex-dependent manner. Overall, inulin increases the proportion of Bacteroides, Blautia, and glycine, while decreasing Eggerthella, Lactococcus, Streptococcus, trimethylamine, 3-hydroxyisobutyrate, leucine and methionine in both sexes. …”

Image_1_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…<p>A comprehensive understanding of the dynamic changes in interleukin-6 (IL-6) levels is essential for monitoring and treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). …”

Image_1_Evaluation of the Anti-Aging Effects of a Probiotic Combination Isolated From Centenarians in a SAMP8 Mouse Model.tif by Xin Fang (134979)

“…<p>Population aging is a prominent global problem in today’s society. …”

Data_Sheet_1_Altered Behaviors and Impaired Synaptic Function in a Novel Rat Model With a Complete Shank3 Deletion.PDF by Tian-Jia Song (6506489)

“…In this study, we established and characterized a novel rat model with a deletion spanning exons 11–21 of Shank3, leading to a complete loss of the major SHANK3 isoforms. …”

Figure 4 from Claudin-4 Modulates Autophagy via SLC1A5/LAT1 as a Mechanism to Regulate Micronuclei by Fabian R. Villagomez (18098633)

“…This analysis utilized publicly available data from HGSOC tumors, sourced from cBioPortal and Kaplan–Meier plotter. <b>A,</b> PPN (based on BioID) of claudin-4-interacting proteins (experimentally determined using STRING) and highly mutated proteins (cBioPortal) in HGSOC tumors shows clusters of proteins and distinctive associated cellular functions. …”

Table 1_Childhood cancer patients' experiences of a structured exercise program. A qualitative study using reflexive thematic analysis.pdf by Dennis Wilke (20936606)

“…Introduction<p>Undergoing cancer treatment as a child, adolescent or young adult involves decreased physical activity and fitness, which may further compromise the bodily and psychosocial well-being of young patients. …”

Image1_Dietary fiber modulates gut microbiome and metabolome in a host sex-specific manner in a murine model of aging.TIFF by Saurabh Kadyan (11383020)

“…The findings demonstrate that inulin exerts prebiotic effects, but in a sex-dependent manner. Overall, inulin increases the proportion of Bacteroides, Blautia, and glycine, while decreasing Eggerthella, Lactococcus, Streptococcus, trimethylamine, 3-hydroxyisobutyrate, leucine and methionine in both sexes. …”

Image_5_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…<p>A comprehensive understanding of the dynamic changes in interleukin-6 (IL-6) levels is essential for monitoring and treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). …”

Impact on functionality of the paliperidone palmitate three-month formulation in patients with a recent diagnosis of schizophrenia: a real-world observational prospective study by Maria Paz Garcia-Portilla (8898926)

“…CGI-Sch severity significantly decreased from a mean score of 2.8 (1.1) at baseline to a score of 2.2 (1.1) at month 12 with a before-and-after difference of −0.6 (95% CI, 0.8 to −0.4, p < 0.001).…”

Occupancy modeling reveals territory-level effects of nest boxes on the presence, colonization, and persistence of a declining raptor in a fruit-growing region by Megan E. Shave (4521208)

“…This study examined the effects of cherry orchard nest boxes on the local breeding population of a declining species, the American Kestrel (<i>Falco sparverius</i>), in a fruit-growing region of Michigan. …”

Image_3_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF by Jian Wu (41301)

“…<p>A comprehensive understanding of the dynamic changes in interleukin-6 (IL-6) levels is essential for monitoring and treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). …”

Supplementary Material for: Superior Mesenteric Artery Syndrome Improved by Enteral Nutritional Therapy: A Retrospective Case-Series Study in a Single Institution by Wan S. (8570061)

“…Serum level of nutritional indicators, BMI and body weight increased after EN therapy. During a median follow-up of 24 months (9–44) after EN therapy, the mean symptom score decreased from 24.28 ± 9.57 to 8.06 ± 8.29 (<i>p</i> < 0.0001), and 65% of patients’ symptoms resolved and 15% of patients’ symptoms improved. …”

DataSheet1_Identification of a Five-mRNA Signature as a Novel Potential Prognostic Biomarker for Glioblastoma by Integrative Analysis.DOCX by Huifang Xu (111603)

“…Moreover, consistent with the bioinformatics analysis, NMB, ABCC3, and MDK mRNA expression was considerably higher in four human GBM cells, and the expression of PTPRN and RALYL was decreased in GBM cells (p < 0.05). Our study developed a novel candidate model that provides new prospective prognostic biomarkers for GBM.…”