A Tale of Switched Functions: From Cyclooxygenase Inhibition to M-Channel Modulation in New Diphenylamine Derivatives by Asher Peretz (44240)

“…Powerful M-channel openers were generated, provided that the diphenylamine moiety and a terminal hydroxyl group are preserved. In transfected CHO cells, they activated recombinant Kv7.2/3 K⁺ channels, causing a hyperpolarizing shift of current activation as measured by whole-cell patch-clamp recording. …”

Image 2_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg by Kaleigh O’Hara (22750082)

“…<p>This research analyzed the sample entropy (SampEn) of breath-by-breath cardiopulmonary exercise testing (CPET) data from 170 healthy pediatric participants (85 males) 8 to 18-years-old, using a Bayesian statistics approach. SampEn measures the complexity of time series data, providing quantitative insight into the predictability of breathing patterns in pediatric participants. …”

The bycatch of piramutaba, Brachyplatystoma vaillantii industrial fishing in a salinity and depth gradient in the Amazon estuary, Brazil by Alexandre Pires MARCENIUK (15376976)

“…<div><p>ABSTRACT The piramutaba, Brachyplatystoma vaillantii is a freshwater catfish that is the most abundant fishery resource in the Amazon estuary. …”

Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach by Yi-Hsien Cheng (4007921)

“…Numerous studies have engineered nanoparticles with different physicochemical properties to enhance the delivery efficiency to solid tumors, yet the mean and median delivery efficiencies are only 1.48% and 0.70% of the injected dose (%ID), respectively, according to a study using a nonphysiologically based modeling approach based on published data from 2005 to 2015. …”

Image 1_Changes in gut flora in patients with epilepsy: a systematic review and meta-analysis.pdf by Xingyan He (20198118)

“…Background<p>Epilepsy is a prevalent chronic neurological disorder that is strongly associated with a wide range of psychological, cognitive and social problems. …”

Evaluating stability of human spine in static tasks: a combined <i>in vivo</i>-computational study by Farshid Ghezelbash (11763515)

“…Muscle forces, trunk stiffness and stability margins were calculated by a nonlinear subject-specific EMG-assisted-optimization musculoskeletal model of the trunk. …”

Data_Sheet_1_A Role for PICKLE in the Regulation of Cold and Salt Stress Tolerance in Arabidopsis.docx by Rong Yang (107028)

“…<p>Arabidopsis PICKLE (PKL) is a putative CHD3-type chromatin remodeling factor with important roles in regulating plant growth and development as well as RNA-directed DNA methylation (RdDM). …”

Table_1_Daylight-driven carbon exchange through a vertically structured microbial community.XLSX by James J. Moran (12893746)

“…Stable isotope proteomic analysis revealed rapid C exchange between cyanobacterial and associated heterotrophic community members during the day with decreased exchange at night. We observed strong diel control on the spatial exchange of freshly fixed C within tightly interacting mat communities suggesting a rapid redistribution, both spatially and taxonomically, primarily during daylight periods.…”

Table2_Metformin Alleviates Airway Hyperresponsiveness in a Mouse Model of Diet-Induced Obesity.xlsx by Chenjuan Gu (12477879)

“…<p>Obese asthma is a unique phenotype of asthma characterized by non-allergic airway hyperresponsiveness (AHR) and inflammation which responds poorly to standard asthma therapy. …”

Table_1_Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome.XLSX by Alejandro Gella (573840)

“…Expression of the AAV-mitoTag in the glutamatergic vestibular neurons of a mouse model of Leigh Syndrome lacking the complex I subunit Ndufs4 allowed us to assess the proteome and acetylome of a subset of susceptible neurons in a well characterized model recapitulating the human disease. …”

Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes by Shiliang Li (298790)

“…The long-term antidiabetic efficacies of <b>5</b> (10 mg/kg, qw) were better than those of the once-weekly trelagliptin and omarigliptin, especially in decreasing the hemoglobin A1c level.…”

Enhanced Filtration Characteristics and Reduced Bacterial Attachment for Reverse Osmosis Membranes Modified by a Facile Method by Nnadiekwe, Chidera C.

“…The original membrane showed a water contact angle of ∼90−100° that was significantly decreased after silane coating: 63° for 3-APS and ∼52° for 6-AHAS. …”
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The Impact of Acute and Chronic Exercise on Immunoglobulins and Cytokines in Elderly: Insights From a Critical Review of the Literature. by Sellami, Maha

“…Our literature analysis revealed that acute endurance exercise resulted in increased secretory salivary immunoglobulin A (SIgA), while acute bouts of muscle strengthening exercise (i.e., isokinetic, eccentric, knee extensor exercise) increased plasma/muscle interleukin (IL)-6, IL-8 and tumor necrosis factor alpha (TNF-α) levels. …”
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Data_Sheet_5_Autonomic Nervous System Function in Anorexia Nervosa: A Systematic Review.docx by Zoe M. Jenkins (11034249)

“…The current review aimed to synthesize the evidence of basal ANS function in individuals with a current diagnosis of AN and those with a previous diagnosis who had achieved weight restoration, as compared to controls.…”

Table2_SFRP1 induces a stem cell phenotype in prostate cancer cells.XLSX by Alberto Losada-García (9136508)

“…SFRP1 is one of the extracellular proteins that modulate the WNT pathway, and it has been identified as a mediator of stromal epithelium communication. …”

Data_Sheet_3_Autonomic Nervous System Function in Anorexia Nervosa: A Systematic Review.docx by Zoe M. Jenkins (11034249)

“…The current review aimed to synthesize the evidence of basal ANS function in individuals with a current diagnosis of AN and those with a previous diagnosis who had achieved weight restoration, as compared to controls.…”

Data_Sheet_4_Autonomic Nervous System Function in Anorexia Nervosa: A Systematic Review.docx by Zoe M. Jenkins (11034249)

“…The current review aimed to synthesize the evidence of basal ANS function in individuals with a current diagnosis of AN and those with a previous diagnosis who had achieved weight restoration, as compared to controls.…”

Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics by Xiangling Chen (6710669)

“…Moreover, immunoprecipitation assays verified a direct interaction between USP9X and NFX1-123. …”

Data_Sheet_2_SAS: A Platform of Spike Antigenicity for SARS-CoV-2.zip by Lu Zhang (50563)

“…Moreover, on the latest South Africa escaping strain (B.1.351), SAS predicted a significant resistance to reference strain at multiple mutated epitopes, agreeing well with the vaccine evaluation results. …”

Effect of sodium/calcium hypochlorite on adhesion and adaptation of fiber posts luted with a dual resin cement by Guilherme Pauletto (16562239)

“…<div><p>Abstract This study aimed to evaluate the effect of different concentrations of sodium hypochlorite (NaOCl) and calcium hypochlorite [Ca(OCl)2] on the bond strength and adaptation of glass fiber posts luted with a dual-curing resin cement. Fifty decoronated premolars were sectioned 14 mm from the apex and endodontically treated. …”