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larger decrease » marked decrease (Expand Search)
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51861
Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study
Published 2022“…MR analysis provided evidence only for a causal role of liver fat and pancreas volume on risk of type 2 diabetes (1.27 [1.08,1.49] or 27% increased risk and 0.76 [0.62,0.94] or 24% decreased risk per 1SD, respectively) and no causal associations with type 1 diabetes.…”
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51862
Table_2_Pelleting of a Total Mixed Ration Affects Growth Performance of Fattening Lambs.DOCX
Published 2021“…Feeding pelleted TMR is a feasible strategy for intensive lamb fattening operations.…”
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51863
Image 1_Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model.tif
Published 2025“…C-C motif chemokine-like receptor 2 (CCRL2) is a unique seven-transmembrane domain receptor that is upregulated by inflammatory signals and mediates leucocyte migration. …”
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51864
Image_1_Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis.TIF
Published 2021“…Patients with pre-existing meibomian gland dysfunction (MGD) had worsened subjective symptoms of dry eye (1.31, 95% confidence interval (CI) [0.66, 1.95], P < 0.0001), a reduced tear break-up time (BUT) (−2.27, 95% CI [−2.66, −1.88], P < 0.0001), and a worse corneal fluorescein staining (CFS) score (0.75, 95% CI [0.5, 1.0], P < 0.0001) after phacoemulsification cataract surgery, whereas in the general population, the subjective symptoms score and CFS remained unchanged and BUT decreased slightly after surgery. …”
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51865
Table_1_A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics.docx
Published 2023“…Background<p>Semen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive. …”
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51866
Dynamin inhibition by dynasore affects LTP, a type of synaptic plasticity due to sustained activity in hippocampus.
Published 2014“…<p><b>A</b>, Dynasore (80 μM, 20 minute perfusion, open triangles) decreases LTP induced by theta-burst stimulation in CA<sub>3</sub>–CA<sub>1</sub> synapses compared to vehicle-treated slices (black circles)(F<sub>1,10</sub> = 9.081, <i>p</i> = 0.013). …”
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51867
Image2_GSK-3 Inhibition Modulates Metalloproteases in a Model of Lung Inflammation and Fibrosis.JPEG
Published 2021“…To the same extent, GSK-3 inhibition blunted the increased MMP-9 and MMP-2 activity induced by pro-fibrotic stimuli in a human lung fibroblast cell line. Moreover, the αSMA protein level, a marker of fibroblast-to-myofibroblast transition involved in fibrosis, was decreased in primary fibroblasts treated with TGFβ following GSK-3 inhibition. …”
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51868
Influence of head and neck position on the performance of supraglottic airway devices: A systematic review and meta-analysis
Published 2019“…</p><p>Study eligibility criteria</p><p>Prospective studies investigating the effects of head and neck positions on the performance of SADs.</p><p>Methods</p><p>A random effect model was applied in the all analyses. …”
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51869
Image_1_Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.tif
Published 2024“…Context<p>Although a monoallelic mutation in the calcium-sensing receptor (CASR) gene causes familial hypocalciuric hypercalcemia (FHH), the functional characterization of the identified CASR mutation linked to the clinical response to calcimimetics therapy is still limited.…”
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51870
Evaluating the effectiveness of safety countermeasures at highway–railway grade crossing based on a machine learning framework
Published 2024“…This approach contributes to a clearer understanding of how each countermeasure impacts collision frequency. …”
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51871
Table_3_A Multilevel Assessment of Plasticity in Response to High-Altitude Environment for Agama Lizards.pdf
Published 2022“…Both lizards were capable of acclimating to the high-altitude environment without sacrificing their performance in bite force, but they also showed high plasticity in tail display behavior by either decreasing the intensity of a specific display component (P. forsythii) or by the trade-off between display components (P. axillaris). …”
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51872
Table_1_FDA Approved Drug Library Screening Identifies Robenidine as a Repositionable Antifungal.pdf
Published 2020“…Indeed, upon robenidine treatment, we found a dose dependent increase in the phosphorylation of the cell wall integrity marker Mkc1, which was decreased after prolonged exposure. …”
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51873
Personal, social, and environmental factors associated with lifejacket wear in adults and children: A systematic literature review
Published 2018“…Lifejackets are routinely recommended as a drowning prevention strategy; however, a review of related factors regarding lifejacket wear has not previously been investigated.…”
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51874
Supplementary Material for: Rosuvastatin Potentiates Gonadotropin-Lowering Effects of Metformin in Postmenopausal Women: A Pilot Study
Published 2023“…<b><i>Results:</i></b> Fifty-three women (18 in groups A and B and 17 in group C) completed the study. …”
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51875
Image_1_Prognostic value of cachexia index in patients with colorectal cancer: A retrospective study.tiff
Published 2022“…The univariate and multivariate Cox regression analysis indicated that older age, low CXI, and coronary heart disease instead of cachexia were associated with a decreased OS.</p>Conclusion<p>CXI was better than cachexia in predicting OS and could be a useful prognostic indicator in patients with colorectal cancer, and greater attention should be paid to patients with low CXI.…”
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51876
MTB-3, a Microtubule Plus-End Tracking Protein (+TIP) of <i>Neurospora crassa</i>
Published 2013“…<div><p>The microtubule (MT) “plus end” constitutes the platform for the accumulation of a structurally and functionally diverse group of proteins, collectively called “MT plus-end tracking proteins” (+TIPs). …”
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51877
The Macroeconomic Consequences of Renouncing to Universal Access to Antiretroviral Treatment for HIV in Africa: A Micro-Simulation Model
Published 2012“…</p> <h3>Results</h3><p>Increased levels of ART coverage result in decreasing HIV incidence and related mortality. Universal access to ART has a positive impact on workers' productivity; the evaluations performed for Swaziland and Cameroon show that universal access would imply net cost-savings at the scale of the society, when the full macroeconomic consequences are introduced in the calculations. …”
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51878
The inhibition of HSP90 reduces the aggregation and cell death caused by mutant A17-PABPN1.
Published 2015“…<p><b>(A, B)</b> 17-AAG decreases PABPN1-induced INIs in myotubes. …”
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51879
MicroRNA-147 Induces a Mesenchymal-To-Epithelial Transition (MET) and Reverses EGFR Inhibitor Resistance
Published 2014“…<div><p>Background</p><p>The epithelial-mesenchymal transition (EMT) is a key developmental program that is often activated during cancer progression and may promote resistance to therapy. …”
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51880
Table_2_Retinal microvasculature features in patients with migraine: a systematic review and meta-analysis.XLSX
Published 2023“…Background<p>Migraine is a central nervous system disorder involving neuronal and vascular factors. …”