MicroRNA-138 Regulates Hypoxia-Induced Endothelial Cell Dysfunction By Targeting S100A1 by Anagha Sen (482673)

“…Bioinformatic analysis suggested that microRNA -138 (MiR-138) could target the 3′UTR of S100A1. Patients with critical limb ischemia (CLI) or mice subjected to femoral artery resection (FAR) displayed increased MiR-138 levels and decreased S100A1 protein expression. …”

Image_2_Identification and characterization of a novel CASR mutation causing familial hypocalciuric hypercalcemia.tif by Chien-Ming Lin (740034)

“…Context<p>Although a monoallelic mutation in the calcium-sensing receptor (CASR) gene causes familial hypocalciuric hypercalcemia (FHH), the functional characterization of the identified CASR mutation linked to the clinical response to calcimimetics therapy is still limited.…”

Cooperation between Monocyte-Derived Cells and Lymphoid Cells in the Acute Response to a Bacterial Lung Pathogen by Andrew S. Brown (110423)

“…We observed that the numbers of alveolar macrophages rapidly decreased after infection coincident with a rapid infiltration of the lung by monocyte-derived cells (MC), which, together with neutrophils, became the dominant inflammatory cells associated with the bacteria. …”

Image_1_A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics.jpg by Yi Guo (35817)

“…Background<p>Semen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive. …”

Potential niche expansion of the American mink invading a remote island free of native-predatory mammals by Ramiro D. Crego (5059097)

“…This may occur under a favorable combination of access to resources that can be further favored by a lack of competitors and a release from natural enemies. …”

The replication initiator protein of a geminivirus interacts with host monoubiquitination machinery and stimulates transcription of the viral genome by Nirbhay Kumar Kushwaha (4405612)

“…<div><p>Geminiviruses constitute a group of plant viruses, with a ssDNA genome, whose replication in the nucleus of an infected cell requires the function of geminivirus-encoded replication initiator protein (Rep). …”

Serum HBV surface antigen positivity is associated with low prevalence of metabolic syndrome: A meta-analysis by Yuanyuan Li (18671)

“…<div><p>Background and aim</p><p>As there is conflicting evidence for the relationship between hepatitis B virus surface antigen (HBsAg) positivity and the prevalence of metabolic syndrome (MetS), we performed a meta-analysis to investigate whether HBsAg positivity affects the incidence of MetS.…”

Taxes on Sugar-Sweetened Beverages to Reduce Overweight and Obesity in Middle-Income Countries: A Systematic Review by Sharon S. Nakhimovsky (3138477)

“…Estimates for own-price elasticity ranged from -0.6 to -1.2, and decreases in SSB consumption ranged from 5 to 39 kilojoules per person per day given a 10% increase in SSB prices. …”

Table_1_Pelleting of a Total Mixed Ration Affects Growth Performance of Fattening Lambs.DOCX by Bo Li (112195)

“…Feeding pelleted TMR is a feasible strategy for intensive lamb fattening operations.…”

Lack of Functional Benefit with Glutamine versus Placebo in Duchenne Muscular Dystrophy: A Randomized Crossover Trial by Elise Mok (264326)

“…<div><h3>Background</h3><p>Oral glutamine decreases whole body protein breakdown in Duchenne muscular dystrophy (DMD). …”

Is rectus abdominis thickness associated with survival among patients with liver cirrhosis? A prospective cohort study by Maria Ciocîrlan (12800283)

“…RA thickness correlated moderately with MAMC (r = 0. 596; P < 0.0001) and HGS (r = 0.515; P < 0.0001) and decreased with increasing SGA class (A, 10.6 ± 2.8 mm; B, 8.3 ± 1.9 mm; C, 6.5 ± 1.9 mm; P < 0.0001). …”

Table_1_Causal effect of iron status on lung function: A Mendelian randomization study.docx by Zhimin Yu (2258896)

“…Summary statistics of these genetic instruments with lung function were extracted from a meta-analysis of UK Biobank and SpiroMeta consortium (N = 400,102). …”

Table_3_Manual Collection and Semen Characterization in a West Indian Manatee (Trichechus manatus).docx by Jonathan R. Cowart (9550121)

“…Therefore, the aim of the study was to fill current gaps in knowledge regarding semen parameters in West Indian manatees by collecting and characterizing multiple ejaculate samples from a single, adult West Indian manatee. Samples were analyzed for the following semen parameters: volume, agglutination, pH, osmolality, viscosity, concentration, total sperm number, motility and kinematic parameters, morphology, plasma membrane integrity, acrosome integrity, chromatin maturation, and chromatin condensation. …”

Table_1_Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina.docx by Lan He (219448)

“…Furthermore, the Babesia LDH sequence is distinct from its bovine homologue and thus a potential chemotherapeutic target that would result in decreasing the ATP supply to the parasite but not to the host. …”

Association of vitamin B6 intake with the risk and prognosis of diabetic retinopathy: a NHANES-based study by Yimeng Ruan (17763457)

“…Multivariate analyses showed that the intake of vitamin B6 was negatively associated with the risk of DR (odds ratio = 0.81, 95% confidence level: 0.69–0.95, <i>p</i> = 0.012), and patients with DR with an increased intake of vitamin B6 had a significantly decreased risk of all-cause death (hazard ratio = 0.81, 95% confidence level: 0.66–0.99, <i>p</i> = 0.041) or cardiovascular disease-related death (hazard ratio = 0.76, 95% confidence level: 0.58–0.98, <i>p</i> = 0.037).…”

DataSheet_1_Inflammatory cytokine profiles in erectile dysfunction: a bidirectional Mendelian randomization.csv by Dongze Liu (12993036)

“…MR-Egger (ME), inverse variance weighting (IVW), and weighted median (WM) were applied to conduct the MR study and IVW was taken as the main criterion.</p>Results<p>From a genetic perspective, the increase of interferon-inducible protein-10 (IP-10) level significantly increased the risk of ED (P=0.043, odds ratio (OR)=1.269, 95% confidence interval (95%CI): 1.007-1.600), while the increase of interleukin-1 receptor antagonist (IL-1RA) markedly decreased the risk of ED (P=0.037, OR=0.768, 95%CI: 0.600-0.984). …”

Omega 3 Fatty Acids Supplementation and Oxidative Stress in HIV-Seropositive Patients. A Clinical Trial by Norma Amador-Licona (2576329)

“…The aim of this study was to assess the effect of omega 3 fatty acids on different markers of oxidative stress in HIV-seropositive patients. We performed a randomized parallel controlled clinical trial in The Instituto Mexicano del Seguro Social, a public health hospital. 70 HIV-seropositive patients aged 20 to 55 on clinical score A1, A2, B1 or B2 receiving highly active antiretroviral therapy (HAART) were studied. …”

Economic and public health impact of decentralized HIV viral load testing: A modelling study in Kenya by M. de Necker (6407402)

“…The GeneXpert system is a diagnostic point-of-care technology that can quantify, amongst others, HIV VL. …”

Plausibility of the zebrafish embryos/larvae as an alternative animal model for autism: A comparison study of transcriptome changes by Sangwoo Lee (1727713)

“…<div><p>Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder characterized by impaired or abnormal social interaction and communication and by restricted and repetitive behaviour. …”

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity by Mohamed Abu-Farha (25322)

“…<div><p>Sedentary lifestyle and excessive energy intake are prominent contributors to obesity; a major risk factors for the development of insulin resistance, type 2 diabetes and cardiovascular diseases. …”