Image_1_Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina.tif by Lan He (219448)

“…Furthermore, the Babesia LDH sequence is distinct from its bovine homologue and thus a potential chemotherapeutic target that would result in decreasing the ATP supply to the parasite but not to the host. …”

<i>In situ</i> Proximity Ligation Assay (PLA) for TUSC2 protein in tumor biopsies (A). by Charles Lu (33589)

“…<p>A synthetic oligopeptide (GASGSKARGLWPFASAA) derived from the N-terminal amino-acid sequence of the TUSC2 protein was used to develop the anti-TUSC2 polyclonal antibody in rabbits used in this study. …”

Image 3_Targeting CCRL2 enhances therapeutic outcomes in a tuberculosis mouse model.tif by Tianyin Wang (10272824)

“…C-C motif chemokine-like receptor 2 (CCRL2) is a unique seven-transmembrane domain receptor that is upregulated by inflammatory signals and mediates leucocyte migration. …”

Table 1_Impact of exercise to treat postural orthostatic tachycardia syndrome: a systematic review.docx by Melissa M. Cortez (17010993)

“…Background<p>Postural orthostatic tachycardia syndrome (POTS) is a chronic condition associated with a high symptom burden and decreased quality of life (QOL). …”

Table_2_Manual Collection and Semen Characterization in a West Indian Manatee (Trichechus manatus).docx by Jonathan R. Cowart (9550121)

“…Therefore, the aim of the study was to fill current gaps in knowledge regarding semen parameters in West Indian manatees by collecting and characterizing multiple ejaculate samples from a single, adult West Indian manatee. Samples were analyzed for the following semen parameters: volume, agglutination, pH, osmolality, viscosity, concentration, total sperm number, motility and kinematic parameters, morphology, plasma membrane integrity, acrosome integrity, chromatin maturation, and chromatin condensation. …”

Video_1_A shift of brain network hub after spinal cord injury.MP4 by Kohei Matsubayashi (17178100)

“…We evaluated “centrality,” a representative parameter of network analysis. …”

Differences in SOM Decomposition and Temperature Sensitivity among Soil Aggregate Size Classes in a Temperate Grasslands by Qing Wang (27728)

“…The <i>Q</i>₁₀ values were highest for MA, followed (in decreasing order) by bulk soil, MF, and MI. Similarly, the activation energies (<i>E_a</i>) for MA, bulk soil, MF, and MI were 48.47, 33.26, 27.01, and 23.18 KJ mol⁻¹, respectively. …”

Image_1_Causal effect of iron status on lung function: A Mendelian randomization study.pdf by Zhimin Yu (2258896)

“…Summary statistics of these genetic instruments with lung function were extracted from a meta-analysis of UK Biobank and SpiroMeta consortium (N = 400,102). …”

Data_Sheet_1_A shift of brain network hub after spinal cord injury.CSV by Kohei Matsubayashi (17178100)

“…We evaluated “centrality,” a representative parameter of network analysis. …”

Supplementary Material for: Gender Disparities in Neurological Symptoms of Long-COVID: A systematic review and meta-analysis by Gorenshtein A. (19418674)

“…Background- Female sex is a known risk factor for long-COVID. With the increasing number of COVID-19 cases, the corresponding number of survivors is also expected to rise. …”

A New Murine Model of Osteoblastic/Osteolytic Lesions from Human Androgen-Resistant Prostate Cancer by Anaïs Fradet (460958)

“…Most of the murine models of mixed lesions derived from prostate cancer cells are androgen sensitive. Thus, we established a new model of CRPC (androgen receptor (AR) negative) that causes mixed lesions in bone.…”

Associations of Lifestyle Factors, Disease History and Awareness with Health-Related Quality of Life in a Thai Population by Prin Vathesatogkit (117760)

“…We examined and compared the effects of different health states on quality of life in a Thai population.</p> <h3>Methods</h3><p>In 2008–2009, 5,915 corporate employees were invited to participate in a survey where HRQoL was measured by the Short Form 36 (SF-36) questionnaire. …”

The efficacy and tolerability of rotigotine on patients with periodic limb movement in sleep: A systematic review and meta-analysis by Meng-Ni Wu (770335)

“…In the pre- and post-intervention studies, the periodic limb movement index was significantly decreased after therapy with rotigotine with a difference in means of −5.866/h (95% CI, −10.570 to −1.162, <i>p</i> = 0.015). …”

Supplementary file 1_Ondansetron: a potential intervention for improving clinical outcomes in stroke patients.docx by Jian Xu (31545)

“…Background<p>Stroke is a major global public - health problem. It is a cerebrovascular disease with sudden onset, high prevalence, and high rates of death and disability. …”

Molecular Characterization of Chronic Lymphocytic Leukemia Patients with a High Number of Losses in 13q14 by Ana Eugenia Rodríguez (120343)

“…This deregulation affected genes involved in apoptosis and proliferation (BCR and NFkB signaling), leading to increased proliferation and decreased apoptosis in 13q-H patients. Deregulation of several microRNAs, such as miR-15a, miR-155, miR-29a and miR-223, was also observed in these patients. …”

Early insights into the characteristics and evolution of clinical parameters in a cohort of patients prescribed sacubitril/valsartan in Germany by Rolf Wachter (326776)

“…Patients with ≥1 heart failure (HF) diagnosis during the study period, ≥1 additional HF diagnosis in the full history of the database, and ≥1 prescription for an angiotensin-converting enzyme inhibitor or angiotensin receptor blocker and a β-blocker during the study period, without a prescription for sac/val (<i>n</i> = 25,264), were included as a reference cohort. …”

Data Sheet 1_Triterpenes in breast cancer: a systematic review of preclinical evidence in rodents.pdf by Alexandra Prodea (22617710)

“…Introduction<p>Breast cancer poses a significant health problem for women worldwide due to late-stage diagnosis, toxicity of standard therapy and drug resistance. …”

Table_1_Causal links between serum micronutrients and epilepsy: a Mendelian randomization analysis.XLSX by Haohao Chen (8070887)

“…Background<p>Micronutrient levels play a critical role in epilepsy. This study investigates the impact of micronutrient levels on epilepsy via Mendelian randomization (MR).…”

Table_1_Retinal microvasculature features in patients with migraine: a systematic review and meta-analysis.docx by Yulian Pang (14002071)

“…Background<p>Migraine is a central nervous system disorder involving neuronal and vascular factors. …”

Data_Sheet_1_A Novel Idiopathic Atrial Calcification: Pathologic Manifestations and Potential Mechanism.docx by Bowen Li (200859)

“…Background<p>Cardiac calcification is a type of ectopic pathologic calcification of unknown etiology and mechanisms. …”