Data Sheet 1_Genetic variation in RYR1 is associated with heart failure progression and mortality in a diverse patient population.docx by Leonardo A. Guerra (20762270)

“…Introduction<p>Heart failure (HF) is a highly prevalent disease affecting roughly 7 million Americans. …”

Supplementary Material for: Secular Trends in the Incidence, Prevalence, and Medications for Epilepsy from 2007 to 2015 in Taiwan: A Nationwide Population-Based Study by Chou I.-J. (11704586)

“…<b><i>Background:</i></b> Patients with epilepsy have a higher mortality rate than the general population. …”

Table 2_Epidemiological trends and future projections of ischemic stroke in children and adolescents: a global analysis from 1990 to 2021.docx by Yi Liu (36759)

“…</p>Results<p>From 1990 to 2021, ischemic stroke in children and adolescents increased globally in incidence and prevalence, while mortality and disability-adjusted life years (DALYs) decreased. The disease burden is higher in low-income countries, with females having higher incidence rates and males bearing a greater burden in mortality and DALYs. …”

Table 1_Epidemiological trends and future projections of ischemic stroke in children and adolescents: a global analysis from 1990 to 2021.docx by Yi Liu (36759)

“…</p>Results<p>From 1990 to 2021, ischemic stroke in children and adolescents increased globally in incidence and prevalence, while mortality and disability-adjusted life years (DALYs) decreased. The disease burden is higher in low-income countries, with females having higher incidence rates and males bearing a greater burden in mortality and DALYs. …”

Differences between positive and negative post-test probabilities of recurrence and their 95% confidence interval for stage II (A) and stage III (B). by Rebeca Sanz-Pamplona (122669)

Binding probability as a function of the concentration of free PRDM9 protein molecules for homozygotes and heterozygotes (mean affinity y = 0.6). by Alice Genestier (18585696)

PyMT-Maclow: A novel, inducible, murine model for determining the role of CD68 positive cells in breast tumor development by Robin M. H. Rumney (4672501)

“…These results demonstrate that depleting CD68⁺ macrophages in an inducible and selective manner delays the development of mammary tumors and that the PyMT-MacLow model is a useful and unique tool for studying the role of TAMs in breast cancer.…”

Effect of costunolide and BIBR1532 on AFP secretion by HepG2/C3A and PLC/PRF/5 cell lines. by Roula Tahtouh (714734)

“…The supernatant was then collected for ELISA. (A) Costunolide (5–50 μM) significantly decreased AFP production in a dose-dependent manner in the supernatants of HepG2/C3A cells after 48 h of treatment, whereas 50 μM costunolide decreased the AFP levels in the supernatant of PLC/PRF/5 cells. …”

Table_1_Seasonal soil-plant nitrogen dynamics of a cordgrass salt marsh in response to coastal embankments in Eastern China.docx by Ge Qin (6295670)

“…., soil net ammonification (R_A) and nitrification (R_N) rate]; and immobilization [e.g., microbial biomass N (MBN)] in embanked and adjacent S. alterniflora natural salt marshes on the coast of Eastern China. …”

DataSheet_1_Bone metabolism and inflammatory biomarkers in radiographic and non-radiographic axial spondyloarthritis patients: a comprehensive evaluation.pdf by Ignacio Gómez-García (18002569)

“…</p>Results<p>R-axSpA patients had decreased plasma levels of P1NP, a marker of bone formation, compared to controls. …”

Data_Sheet_1_The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction.docx by Fuxin Zhong (12071588)

“…Background<p>Epilepsy is a common neurological disease, and excessive mitophagy is considered as one of the major triggers of epilepsy. …”

Data_Sheet_1_Did the sweetness of beverages change with the Chilean Food Labeling and Marketing Law? A before and after study.docx by Natalia Rebolledo (14022549)

“…Using fixed-effects models, we compared the observed post-law purchases to a counterfactual based on pre-law trends. We found that NNS sweetness increased relative to the counterfactual, while total sugars sweetness decreased after the law. …”

<b>Climate warming, rather than nitrogen deposition, reduces plant diversity and increases community homogenization in a desert steppe</b> by Yi Zhu (22625741)

“…<p dir="ltr">It is still unclear how increasing nitrogen (N) deposition, climate warming, and their interaction affect biotic impoverishment (decreases in α-diversity) and homogenization (decreases in β-diversity) of plant communities at taxonomic, functional, and phylogenetic levels. …”

A Dual Role for Corneal Dendritic Cells in Herpes Simplex Keratitis: Local Suppression of Corneal Damage and Promotion of Systemic Viral Dissemination by Kai Hu (311882)

“…In addition, while HSV infection resulted in significant corneal nerve destruction, local depletion of cDCs resulted in a much more severe loss of corneal nerves. Further, local cDC depletion resulted in decreased corneal nerve infection, and subsequently decreased and delayed systemic viral transmission in the trigeminal ganglion and draining lymph node, resulting in decreased mortality of mice. …”

The Influence of Social Network Characteristics on Peer Clustering in Smoking: A Two-Wave Panel Study of 19- and 23-Year-Old Swedes by Alexander Miething (3211032)

“…</p><p>Methods</p><p>The analysis was based on a Swedish two-wave survey sample comprising ego-centric network data. …”

Data_Sheet_1_Functional Alterations in the Posterior Insula and Cerebellum in Migraine Without Aura: A Resting-State MRI Study.DOCX by Jun Ke (1537273)

“…DC was analyzed voxel-wise and compared between groups, and FC of regions with DC differences were further examined using a seed-based approach.</p><p>Results: Compared with the control group, the migraine group showed increased and decreased DC in the right posterior insula and left crus I, respectively. …”

Expression of Protein Kinase C Isoforms in Pancreatic Islets and Liver of Male Goto-Kakizaki Rats, a Model of Type 2 Diabetes by Mohammed Seed Ahmed (798933)

“…<div><p>Protein kinase C (PKC) is a family of protein kinases controlling protein phosphorylation and playing important roles in the regulation of metabolism. …”

The intracalcarine cortex and temporal pole exhibited a positive association between age and deactivation level in the pooled young and older adults group. by Fatemeh Noohi (7378112)

“…<p>The colored voxels show the brain regions in which the BOLD signal was significantly decreased from rest to stimulation in a manner that was correlated with age. …”

Brain gray and white matter abnormalities in preterm-born adolescents: A meta-analysis of voxel-based morphometry studies - Fig 3 by Le Zhou (173199)

Serotype-Specific Changes in Invasive Pneumococcal Disease after Pneumococcal Conjugate Vaccine Introduction: A Pooled Analysis of Multiple Surveillance Sites by Daniel R. Feikin (153640)

“…Increases in non-vaccine-serotype (NVT) IPD rates occurred in some sites, presumably representing serotype replacement. We used a standardized approach to describe serotype-specific IPD changes among multiple sites after PCV7 introduction.…”